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Melanomas express B7-H1 protein to hide from T-cells

Johns Hopkins and Yale scientists have found that melanoma cells use a cloaking protein to hide from immune cells poised to attack the cancer. Nearly 40 percent of their sampling of melanoma tissues contained the B7-H1 protein, also called PD-L1, and scientists say it could be used as a target for new therapies.

26 Apr 2012

Romney sweeps 5 GOP primaries, moves closer to presidential nomination

Meanwhile, news outlets report on criticism aimed at Senate Minority Leader Mitch McConnell, R-Ky., and action in congressional races in Arizona and Pennsylvania.

26 Apr 2012

Study examines reasons why individuals misreport smoke alarm coverage

One in three households in Baltimore misreports its smoke alarm coverage, with the vast majority of errors due to over-reporting coverage, according to a study by researchers from the Johns Hopkins Center for Injury Research and Policy. Reasons for over-reporting included study participants incorrectly assuming all of their alarms were working because they weren't beeping, and not having alarms on every level of the home.

26 Apr 2012

Draft farm bill includes 'promising' fixes to U.S. food aid system

In this post in the Center for Global Development's (CDG) "Rethinking U.S. Foreign Assistance Blog," Connie Veillette, director of CGD's rethinking U.S. foreign assistance initiative, comments on a draft farm bill released by Congress last week, which she writes "includes some promising fixes to the notoriously inefficient U.S. food aid system."

26 Apr 2012

Fragile-X gene linked with disrupting de novo mutations in children with autism

A team led by scientists at Cold Spring Harbor Laboratory (CSHL) publishes research today indicating a striking association between genes found disrupted in children with autism and genes that are targets of FMRP, the protein generated by the gene FMR1, whose dysfunction causes Fragile-X syndrome.

26 Apr 2012

Studies: Against best advice, docs continue unneeded prostate screenings

JAMA and another journal found that despite government recommendations, doctors continue to screen too many men for prostate cancer.

26 Apr 2012

Cardiovascular emergencies may benefit from regionalized systems of care

Experts are proposing a new model of care collaboration to diagnosis, treat and follow patients who present with various emergent cardiovascular conditions which require rapid, resource-intensive care and confer a high risk of mortality, in an article published April 24 in Circulation.

26 Apr 2012

Australian Government must take the lead in tackling antibiotic resistance: NPS Board Chair Dr Janette Randall address to the National Press Club

NPS Board Chair Dr Janette Randall today called on the government to take the lead on a cross sectoral approach towards tackling the antibiotic-resistance crisis facing the Australian community.

26 Apr 2012

Funding for HIV programs among MSM populations lacking, largely due to stigma

"Despite high prevalence rates of HIV among men who have sex with men (MSM), funding for HIV prevention, treatment and care consistently neglects these populations, often due to stigma and discrimination," Owen Ryan, deputy director of public policy at amfAR, the Foundation for AIDS Research, writes in this guest post in the Funders Concerned About AIDS blog.

26 Apr 2012

White potato consumption does not cause diabetes, obesity

Preliminary Research presented today at The Federation of American Societies for Experimental Biology (FASEB) Conference in San Diego demonstrates that habitual consumption of white potatoes (baked, boiled and mashed) is not associated with obesity, type 2 diabetes or levels of C-reactive protein, a marker of systemic inflammation once potential confounding factors are controlled for (e.g., age, gender, and education).

26 Apr 2012

Iowa House approves mental health reforms

The bill would replace the county-by-county system in Iowa. Also in state legislative news, N.H. gubernatorial candidate opposes health care compact proposal and California lawmaker seeks cap on consumers' prescription drug expenses.

26 Apr 2012

Researchers identify new components of genetic pathway that controls neural stem cells

Can one feel too attached? Does one need to let go to mature? Neural stem cells have this problem, too. As immature cells, neural stem cells must stick together in a protected environment called a niche in order to divide so they can make all of the cells that populate the nervous system. But when it's time to mature, or differentiate, the neural stem cells must stop dividing, detach from their neighbors and migrate to where they are needed to form the circuits necessary for humans to think, feel and interact with the world.

26 Apr 2012

Study: Fewer employers offer health benefits for workers

Fewer employers are offering healthcare coverage and fewer employees are taking it, a new study reports.

26 Apr 2012

CEHC develops list of ten chemicals that contribute to autism, learning disabilities

An editorial published today in the prestigious journal Environmental Health Perspectives calls for increased research to identify possible environmental causes of autism and other neurodevelopmental disorders in America's children and presents a list of ten target chemicals including which are considered highly likely to contribute to these conditions.

26 Apr 2012

State roundup: Calif. exchanges forge ahead; Mo. grappling with costs, quality

Despite a potentially disruptive U.S. Supreme Court Decision expected this summer, California officials are moving forward with the creation of a new, online health insurance market. ... "There are many different scenarios," said David Panush, director of government relations for the California Health Benefit Exchange. "Rather than trying to crystal-ball what the court may or may not do, we've got our foot on the pedal and we're going full speed ahead."

26 Apr 2012

U-M’s second human embryonic stem cell line now available for federally-funded research

The University of Michigan's second human embryonic stem cell line has just been placed on the U.S. National Institutes of Health's registry, making the cells available for federally-funded research. It is the second of the stem cell lines derived at U-M to be placed on the registry.

26 Apr 2012

Opinion pieces recognize World Malaria Day

Wednesday, April 25, marks World Malaria Day, which this year has the theme "Sustain Gains, Save Lives: Invest in Malaria." The following opinion pieces address the fight against malaria.

26 Apr 2012

First-ever study to evaluate effects of interaction between metamphetamines and Ibudilast

John W. Tsuang, M.D., principal investigator at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed), in conjunction with Steven J. Shoptaw, Ph.D., from the UCLA Department of Family Medicine, is spearheading a Phase I clinical safety trial that for the first time examines the effects of Ibudilast when administered with metamphetamine (MA), an addictive stimulant that is closely related to amphetamine.

26 Apr 2012

Hospital debt collector puts 'the squeeze' on patients

A report released Tuesday by the Minnesota Attorney General spotlights aggressive practices used by one of the nation's largest collectors of medical debts, including demanding payments from people seeking care in emergency rooms, cancer wards and delivery rooms.

26 Apr 2012

Robot assisted laparoscopic radical prostatectomy better than other surgical techniques

Outcomes from use of a robot to assist surgeons in removal of a cancerous prostate are at least as good, if not better, than the other two techniques used for a radical prostatectomy -- open or laparoscopic surgery -- according to a large meta analysis led by researchers at NewYork-Presbyterian/Weill Cornell.

26 Apr 2012