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Differentiated luminal-like breast cancer cells can generate larger tumors

New findings in breast cancer research by an international team of scientists contradict the prevailing belief that only basal-like cells with stem cell qualities can form invasive tumors. Research led by Ole William Petersen at the University of Copenhagen (CU) and Mina Bissell of the Lawrence Berkeley National Laboratory (Berkeley Lab) and has shown that luminal-like cells with no detectable stem cell qualities can generate larger tumors than their basal-like counterparts.

19 Apr 2012

Autologous BMMNCs reduce vascular growth in patients with diabetes

Autologous (self-donated) mononuclear cells derived from bone marrow (BMMNCs) have been found to significantly induce vascular growth when transplanted into patients with diabetes who are suffering from critical limb ischemia caused by peripheral artery disease (PAD), a complication of diabetes.

19 Apr 2012

Results from Presidio’s PPI-668 Phase 1a-1b trial on chronic HCV

Presidio Pharmaceuticals, Inc. announced results today from a Phase 1a-1b clinical trial of PPI-668, a potent, pan-genotypic HCV NS5A inhibitor being developed for the treatment of patients with chronic hepatitis C.

19 Apr 2012

Study: 1 in 5 cancer patients may experience ‘breakdowns’ in their care

Cancer care is increasingly complex, and as many as one in five cancer patients may experience "breakdowns" in their care, according to a new study in the Journal of Clinical Oncology. Such breakdowns include communication problems between patients and their care providers, as well as more traditional medical errors; both types of problems can create significant harms. In the study, communication problems outnumbered problems with medical care.

19 Apr 2012

Veterans with killing experience more likely to report suicidal thoughts

The experience of killing in war was strongly associated with thoughts of suicide, in a study of Vietnam-era veterans led by researchers at the San Francisco VA Medical Center (SFVAMC) and the University of California, San Francisco.

19 Apr 2012

Fluorescent fish shows oestrogenic chemicals’ impact on human body

Understanding the damage that pollution causes to both wildlife and human health is set to become much easier thanks to a new green-glowing zebrafish. Created by a team from the University of Exeter, the fish makes it easier than ever before to see where in the body environmental chemicals act and how they affect health.

19 Apr 2012

Myomatrix 2012 conference to take place from April 22-24

The nation's leading scientists and clinicians exploring treatment breakthroughs for congenital muscular dystrophy will convene April 22-24 on the campus of the University of Nevada, Reno, where research by Dean Burkin has led to a potential therapy.

19 Apr 2012

Poll: 80% of American voters favor national school nutrition standards

Eighty percent of American voters favor national standards that would limit calories, fat, and sodium in snack and - la carte foods sold in U.S. schools and encourage the consumption of fruits, vegetables and low-fat dairy items, according to a new poll commissioned by the Kids' Safe & Healthful Foods Project, a joint project of The Pew Charitable Trusts and the Robert Wood Johnson Foundation.

19 Apr 2012

Positive results from CrystalGenomics’ CG100649 Phase 2b OA study

CrystalGenomics, Inc., a biopharmaceutical company headquartered in Korea, has just announced positive results from the Phase 2b osteoarthritis (OA) study of the CG100649, CrystalGenomics' next-generation NSAID candidate.

19 Apr 2012

Link between hypertension drug adherence and total costs of care

Although adherence to hypertension medications was significantly associated with lower hospitalization rates, the total costs of care are higher for adherent patients than for patients who were deemed "non-adherent," according to a new study from pharmacy benefit manager Prime Therapeutics that will be presented this week at the Academy of Managed Care Pharmacy (AMCP)'s 24th Annual Meeting & Expo in San Francisco.

19 Apr 2012

Exactech selects MMI to evaluate novel cartilage repair treatment

Medical Metrics Inc, (MMI), an experienced provider of medical imaging core lab services for global clinical trials, has been selected by Exactech, Inc. to conduct an independent evaluation of medical images from the BiPhasic Cartilage Repair Implant (BiCRI) IDE Clinical Trial approved by the Taiwan FDA.

19 Apr 2012

Scientists identify hypervirulent Salmonella bacteria

UC Santa Barbara researchers have discovered Salmonella bacteria that are up to 100 times more capable of causing disease. Their findings may help prevent food poisoning outbreaks that continue to plague public health and the food industry.

19 Apr 2012

Cruciferous vegetables protect and improve breast cellular health

Broccoli, cabbage, leafy greens, cauliflower-your mother insisted they were good for you while you defiantly pushed them around your plate. Perhaps you didn't believe they were all that good for you. If they're so great, why don't they taste better? Turns out your mother was right. These cruciferous vegetables have a profound influence on the health of your body's cells. In fact, a recent study by Vanderbilt University's Ingram Center showed that a diet full of cruciferous vegetables protects and improves breast cellular health.

19 Apr 2012

Link between insomnia and severity of perceived tinnitus symptoms

For the more than 36 million people plagued by tinnitus, insomnia can have a negative effect on the condition, worsening the functional and emotional toll of chronic ringing, buzzing, hissing or clicking in the head and ears, according to a new study from Henry Ford Hospital in Detroit.

19 Apr 2012

Ten tips to avoid or treat common medical problems in the outdoors

"Good fortune favors the well prepared," says Paul S. Auerbach, MD, a founder and past President of the Wilderness Medical Society and editor of Wilderness Medicine, 6th Edition, recently published by Elsevier. With some advance reading, individuals planning vacations or outdoor excursions can become familiar with adverse situations and be prepared to handle them.

19 Apr 2012

Global summit on international breast health to take place from Oct. 3-5

Supportive care and quality-of-life issues should be considered essential elements of a multidisciplinary approach to breast cancer treatment at the point of breast cancer diagnosis. However, for women suffering from breast cancer in low- and middle-resource countries and other medically underserved areas around the world, this fundamental area of patient care generally is neglected and misunderstood.

19 Apr 2012

New genetic signature may predict NSCLC patients at risk of relapse

A new genetic signature identified by Spanish researchers may provide doctors with robust and objective information about which patients with early stage lung cancer are at low or high risk of relapse following surgery, investigators report at the 3rd European Lung Cancer Conference in Geneva. Their work also opens new avenues for immunotherapy for lung cancer.

19 Apr 2012

Parents play a crucial role in shaping good childhood eating habits

Obesity among children has long been a rising problem in large parts of the world. Parents play a crucial role in shaping good childhood eating habits, according to new research from the University of Stavanger.

19 Apr 2012

Impax announces data from IPX066 Phase III study on Parkinson's

Impax Pharmaceuticals, the branded products division of Impax Laboratories, Inc., today announced that data from the ASCEND-PD Phase III clinical study involving IPX066 will be presented in a Platform Presentation at the 64th Annual Meeting of the American Academy of Neurology in New Orleans, Louisiana, held from April 21 to April 28.

19 Apr 2012

Researchers extract structural information from triple helix DNA in gas phase

A team of researchers at the Institute for Research in Biomedicine (IRB Barcelona) and the Barcelona Supercomputing Center (BSC) have managed for the first time to extract trustworthy structural information from a triple helix DNA in gas phase, that is to say in conditions in which DNA is practically in a vacuum.

19 Apr 2012