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New study recommends intraoperative histological evaluation for Hirschsprung disease treatment

Hirschsprung disease occurs when nerve cells in the colon do not develop normally before birth and the bowel is unable to move its contents along. Severe bowel obstruction and even perforation can then occur. The condition is usually diagnosed within the first months of life, but can be found in older children as well.

18 Apr 2012

Simple, cost-effective saliva test to detect oral cancer

A Michigan State University surgeon is teaming up with a Lansing-area dental benefits firm on a clinical trial to create a simple, cost-effective saliva test to detect oral cancer, a breakthrough that would drastically improve screening and result in fewer people dying of the world's sixth most common cancer.

18 Apr 2012

Medical societies bracing for Medicare penalties

After earning hundreds of millions of dollars through Medicare incentive programs designed to improve the quality of care and hold down costs, the medical profession now worries about the flip side of bonuses - financial penalties from all angles.

18 Apr 2012

Levodopa-carbidopa intestinal gel better than standard oral form to treat advanced Parkinson's disease

A levodopa-carbidopa intestinal gel (LCIG) works better than standard oral levodopa-carbidopa in reducing "off" time in patients with advanced Parkinson's disease.

18 Apr 2012

US DoD awards UC researchers $3.7M grant to study circadian rhythms

Researchers from the University of Cincinnati (UC) have received a four-year, $3.7 million grant from the U.S. Department of Defense for investigations into circadian rhythms that could lead to enhanced understanding of disease treatments, trauma care and human combat performance.

18 Apr 2012

Genetic reach of autism may extend to half siblings

When a child has autism, siblings are also at risk for the disorder. New research from Washington University School of Medicine in St. Louis shows that the genetic reach of the disorder often extends to half siblings as well.

18 Apr 2012

State insurance exchange implementation faces challenges

In some places, state-level progress in building the law's insurance exchanges appears to be stalling because of political divisions.

18 Apr 2012

Study demonstrates how Parkinson's disease protein can spread in patient's brain

Last year, researchers from the Perelman School of Medicine at the University of Pennsylvania found that small amounts of a misfolded brain protein can be taken up by healthy neurons, replicating within them to cause neurodegeneration. The protein, alpha-synuclein (a-syn), is commonly found in the brain, but forms characteristic clumps called Lewy bodies, in neurons of patients with Parkinson's disease (PD) and other neurodegenerative disorders.

18 Apr 2012

Genetically modified mouse mimics key features of Charcot-Marie-Tooth disease

A team of scientists from the University of Missouri created a genetically modified mouse that mimics key features of Charcot-Marie-Tooth disease, an inherited neuromuscular disease affecting approximately 150,000 people in the United States.

18 Apr 2012

New text on nursing of autism spectrum disorder

The growing number of children and adults on the autism spectrum represent a growing need for quality health care that is sensitive to the issues they face. This is the premise and challenge behind a new text, Nursing of Autism Spectrum Disorder: Evidence-based Integrated Care across the Lifespan (Springer, April 2012), edited by Dr. Ellen Giarelli, an associate professor in Drexel's College of Nursing and Health Professions, with Dr. Marcia Gardner.

18 Apr 2012

Federal officials use health law to cite two insurers for excessive premium increases

The insurance companies will be able to charge the higher amount, but they will be required to disclose on websites that reviewers found the rates to be unreasonable and explain why they are still imposing them.

18 Apr 2012

FDA's three draft guidances on biosimilars - BIO submits comments

The Biotechnology Industry Organization (BIO) submitted comments yesterday to the U.S. Food and Drug Administration (FDA) on three draft guidance documents on biosimilar products.

18 Apr 2012

MD Anderson develops series of food plate worksheets on nutrition and cancer prevention

As part of National Minority Cancer Awareness Week during April 15 to 21, The University of Texas MD Anderson Cancer Center has developed a series of food plate worksheets that focus on nutrition and cancer prevention for African American, Hispanic and Vietnamese audiences.

18 Apr 2012

Medical journals facing raft of ethical, transparency challenges

The New York Times, Connecticut Mirror and MedPage Today examine how prominent journals are handling questions about their independence or integrity.

18 Apr 2012

Early intervention of biologic therapies improves outcome for Crohn's disease

A large-scale study of medical claims data shows that introducing sophisticated biologic therapies early in the course of treatment for Crohn's disease improves response to medication and reduces the need for surgery.

18 Apr 2012

Medgenics seeks IND approval to initiate EPODURE Biopump Phase IIb anemia study in ESRD patients

Medgenics, Inc., the developer of a novel technology for the sustained production and delivery of therapeutic proteins in patients using their own tissue, today announced that it has filed an Investigational New Drug application with the U.S. Food and Drug Administration to initiate a Phase IIb multi-center, 100-patient clinical trial.

18 Apr 2012

NSCLC drug regimen approved in 2006 does not improve survival for older patients

Analysis of a drug regimen approved by the F.D.A. in 2006 for the treatment of non-small cell lung cancer (bevacizumab added to the standard chemotherapy regimen carboplatin and paclitaxel) finds Medicare insured patients age 65 years and older who received this regimen did not have improved survival compared to patients who received the standard treatment of carboplatin and paclitaxel alone, according to a study in the April 18 issue of JAMA.

18 Apr 2012

Excessive alcohol use associated with lower self-reporting of maturity

Tipping back one too many cocktails during an individual's early 20s doesn't correlate to a personal sense of immaturity; however if this habit doesn't stop as they reach age 30, young adults can feel psychologically underdeveloped, according to a University of Missouri study. Helping young adults acknowledge their mental impulse to "sober up" as they mature can improve substance abuse intervention programs.

18 Apr 2012

U.S. Chamber of Commerce finds small business owners wary of health law regs

The survey finds that the regulations rank at the top of small business owners' concerns. In other news, the National Journal examines the future of accountable care organizations.

18 Apr 2012

Kaposi's sarcoma-associated herpesvirus senses and reacts to host cell's impending death

A research team led by Children's National Medical Center has identified a trigger that causes latent Kaposi's sarcoma-associated herpesvirus (KSHV) to rapidly replicate itself. KSHV causes Kaposi's sarcoma, primary effusion lymphoma, and other cancers that commonly affect immunocompromised patients, including those with AIDS.

18 Apr 2012

Medical News

New study recommends intraoperative histological evaluation for Hirschsprung disease treatment

Simple, cost-effective saliva test to detect oral cancer

Medical societies bracing for Medicare penalties

Levodopa-carbidopa intestinal gel better than standard oral form to treat advanced Parkinson's disease

US DoD awards UC researchers $3.7M grant to study circadian rhythms

Genetic reach of autism may extend to half siblings

State insurance exchange implementation faces challenges

Study demonstrates how Parkinson's disease protein can spread in patient's brain

Genetically modified mouse mimics key features of Charcot-Marie-Tooth disease

New text on nursing of autism spectrum disorder

Federal officials use health law to cite two insurers for excessive premium increases

FDA's three draft guidances on biosimilars - BIO submits comments

MD Anderson develops series of food plate worksheets on nutrition and cancer prevention

Medical journals facing raft of ethical, transparency challenges

Early intervention of biologic therapies improves outcome for Crohn's disease

Medgenics seeks IND approval to initiate EPODURE Biopump Phase IIb anemia study in ESRD patients

NSCLC drug regimen approved in 2006 does not improve survival for older patients

Excessive alcohol use associated with lower self-reporting of maturity

U.S. Chamber of Commerce finds small business owners wary of health law regs

Kaposi's sarcoma-associated herpesvirus senses and reacts to host cell's impending death

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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