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Overcoming challenges to health law implementation at federal, state levels

The Centers for Medicare & Medicaid Services is central to implementing the health law, which leads to questions about its capabilities and resources. Meanwhile, states await a final rule on health exchanges.

12 Mar 2012

Human diseases with Drosophila counterparts discussed at annual conference

More than two-thirds of human genes have counterparts in the well-studied fruit fly, Drosophila melanogaster, so although it may seem that humans don't have much in common with flies, the correspondence of our genetic instructions is astonishing. In fact, there are hundreds of inherited diseases in humans that have Drosophila counterparts.

12 Mar 2012

Masimo announces acquisition of Spire Semiconductor

Masimo, the inventor of Masimo Rainbow Pulse CO-Oximetry, Masimo Rainbow Acoustic Monitoring, and Masimo SET Measure-Through Motion and Low Perfusion pulse oximetry, today announced it has acquired substantially all of the assets of Spire Semiconductor, LLC, maker of advanced light emitting diode and other advanced component-level technologies.

12 Mar 2012

HemaQuest closes $13 million extension of Series B financing

HemaQuest Pharmaceuticals, Inc., a biotechnology company focused on developing small molecule therapeutics to treat hemoglobin disorders, announced today that it has closed a $13 million extension of their Series B financing.

12 Mar 2012

ACRONET joins Medidata Partner Program

As clinical trial activity in the Asia Pacific region continues to expand and contract research organizations (CRO) increasingly provide sponsors with a range of strategic services and support, ACRONET joined the Medidata Partner Program to enhance its technology offerings across the clinical development process.

12 Mar 2012

New research could provide roadmap for more effective drug discovery for CF

A recent study led by Gergely Lukacs, a professor at McGill University's Faculty of Medicine, Department of Physiology, and published in the January issue of Cell, has shown that restoring normal function to the mutant gene product responsible for cystic fibrosis (CF) requires correcting two distinct structural defects. This finding could point to more effective therapeutic strategies for CF in the future.

12 Mar 2012

Many Americans deficient in magnesium, sulfur and sulfate

Many Americans are deficient in magnesium, sulfur and sulfate, experts say. It's a problem that causes a variety of health issues that could be prevented with small changes to diet and behavior, including frequent soaks in Epsom salt.

12 Mar 2012

Cancer Research UK disappointed over SMC ruling against advanced prostate cancer drug

Cancer Research UK is extremely disappointed that the advanced prostate cancer drug, abiraterone, has been ruled too expensive for routine use by the Scottish Medicines Consortium (SMC).

12 Mar 2012

USAID annual letter discusses global health initiatives

PSI's "Healthy Lives" blog presents global health-related excerpts of USAID Administrator Rajiv Shah's annual letter that was published on March 9.

12 Mar 2012

Simple device for disinfecting stethoscopes

According to the Centers for Disease Control and Prevention (CDC) 1,900,000 people contract infections in hospitals, (Hospital Acquired Infections - HAIs) every year and well over 99,000 die as a result; more deaths than from AIDS, breast cancer and auto accidents combined.

12 Mar 2012

Pfizer’s Prevnar 13 Phase 3 study for pneumococcal disease meets all study endpoints

Pfizer Inc. announced today that data from a Phase 3 study of Prevnar 13 (Pneumococcal 13-valent Conjugate Vaccine [Diphtheria CRM197 Protein]) met all study endpoints, showing immunogenicity and establishing a safety profile in children and adolescents aged 5 through 17 years.

12 Mar 2012

BDSI announces postponement of ONSOLIS U.S. relaunch

BioDelivery Sciences International, Inc. today announced that the U.S. relaunch of ONSOLIS (fentanyl buccal soluble film) is being postponed until the product formulation can be modified to address two appearance issues raised by the U.S. Food and Drug Administration (FDA) following a recent inspection of the Aveva manufacturing facility where ONSOLIS is produced.

12 Mar 2012

India plans to increase annual health care spending with aim of providing free care to citizens

"With its health-care system increasingly eclipsed by rivals, India has a plan to nearly double public spending on health over the next five years," a goal that would "lift annual spending on health to 2.5 percent of the country's economic output, from 1.4 percent," the Washington Post reports.

12 Mar 2012

FDA approves Organogenesis oral soft tissue regeneration product, GINTUIT

Today Organogenesis Inc., a business leader in the regenerative medicine field, announced that the United States Food and Drug Administration (FDA) has approved GINTUIT (Allogeneic Cultured Keratinocytes and Fibroblasts in Bovine Collagen), a cell-based product that has been shown to predictably generate new and aesthetically appealing oral soft tissue (gum tissue).

12 Mar 2012

OPKO Health, Scripps Research partner to commercialize Parkinson's disease compound, SR 3306

The Scripps Research Institute and OPKO Health, Inc. today announced a global agreement for the development and commercialization of SR 3306, a novel compound discovered by scientists from the Florida campus of The Scripps Research Institute that blocks the destruction of brains cells in animal models of Parkinson's disease.

12 Mar 2012

Insulin and nutrition keep blood stem cells from differentiating into mature blood cells

UCLA stem cell researchers have shown that insulin and nutrition keep blood stem cells from differentiating into mature blood cells in Drosophila, the common fruit fly, a finding that has implications for studying inflammatory response and blood development in response to dietary changes in humans.

12 Mar 2012

Watson commences Esmya Phase 3 trial in women with anemia linked to uterine leiomyomas

Watson Pharmaceuticals, Inc. today announced it has initiated its Phase 3 trial to evaluate the efficacy and safety of Esmya (ulipristal acetate) in women with anemia associated with uterine leiomyomas, a medical condition often referred to as uterine fibroids (myomas). Leiomyomata are benign solid tumors that often lead to excessive menstrual bleeding, anemia and pain, which ultimately may require surgical intervention.

12 Mar 2012

Salk scientists' discovery explains how a class of chemotherapy drugs works

The well-being of living cells requires specialized squads of proteins that maintain order. Degraders chew up worn-out proteins, recyclers wrap up damaged organelles, and-most importantly-DNA repair crews restitch anything that resembles a broken chromosome. If repair is impossible, the crew foreman calls in executioners to annihilate a cell. As unsavory as this last bunch sounds, failure to summon them is one aspect of what makes a cancer cell a cancer cell.

12 Mar 2012

Thermo Fisher Scientific introduces integrated capillary high-pressure ion chromatography system

Thermo Fisher Scientific Inc., the world leader in serving science, today announced the Thermo Scientific Dionex ICS-4000, the world's first commercially available integrated capillary high-pressure ion chromatography (HPIC) system, incorporating multiple detector options in one instrument.

From Thermo Fisher Scientific Inc. 12 Mar 2012

State abortion bills keep coming

Some call such legislation an "overreach," but at least some of the proposals are getting political traction, including a push in Washington State this week to require insurance plans to cover abortion.

12 Mar 2012