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Matrix protein tenascin C regulates astrocyte development

How astrocytes, certain cells of the nervous system, are generated was largely unknown up to now. Bochum's researchers have now investigated what influence the cell environment, known as the extracellular matrix, has on this process.

13 Dec 2011

High-intensity intermittent exercise lowers blood sugar levels in type 2 diabetics

Researchers at McMaster University have found that brief high intensity workouts, as little as six sessions over two weeks, rapidly lower blood sugar levels in type 2 diabetics, offering a potential fix for patients who struggle to meet exercise guidelines.

13 Dec 2011

Scientists identify gene mutation behind Waldenstrom's macroglobulinemia

Scientists at Dana-Farber Cancer Institute have identified a gene mutation that underlies the vast majority of cases of Waldenstrom's macroglobulinemia, a rare form of lymphoma that has eluded all previous efforts to find a genetic cause.

13 Dec 2011

DNA sequencing identifies new altered genes that drive CLL

The most comprehensive search to date of DNA abnormalities in chronic lymphocytic leukemia (CLL) has unearthed several new altered genes that drive this common blood cancer, a finding that could potentially help doctors predict whether an individual patient's disease will progress rapidly or remain indolent for years, say scientists from Dana-Farber Cancer Institute and the Broad Institute.

13 Dec 2011

Brain atrophy is evident in Parkinson's patients with MCI

Atrophy in the hippocampus, the region of the brain known for memory formation and storage, is evident in Parkinson's disease (PD) patients with cognitive impairment, including early decline known as mild cognitive impairment (MCI), according to a study by researchers in the Perelman School of Medicine at the University of Pennsylvania.

13 Dec 2011

NJ underserved children less likely to receive dental care

When it comes to receiving dental care, New Jersey has its share of underserved children, according to a Rutgers study.

13 Dec 2011

Intertwined diseases may both contribute to cognitive decline in Parkinson's

A method of classifying brain atrophy patterns in Alzheimer's disease patients using MRIs can also detect cognitive decline in Parkinson's disease, according to a new study by researchers from the Perelman School of Medicine at the University of Pennsylvania. Researchers also found that higher baseline Alzheimer's patterns of atrophy predicted long-term cognitive decline in cognitively normal Parkinson's patients.

13 Dec 2011

Scientists identify A2bAR as possible new therapeutic target against atherosclerosis

Researchers from Boston University School of Medicine (BUSM) have identified for the first time the A2b adenosine receptor (A2bAR) as a possible new therapeutic target against atherosclerosis resulting from a diet high in fat and cholesterol.

13 Dec 2011

Research describes advantages of new vaccine adjuvant

New research from the laboratory of Dr. Elizabeth Leadbetter at the Trudeau Institute may lead to a whole new class of vaccines. Dr. Leadbetter's lab has discovered new properties of a potential vaccine adjuvant that suggest it could be useful for enhancing protection against a number of different infections.

13 Dec 2011

Acurian, Onconova sign Clinical Trial Liaison Services agreement

Acurian, Inc., a leading, full-service provider of global patient recruitment and retention solutions, announced today that it has signed an agreement with Onconova Therapeutics, Inc., a private biopharmaceutical company located in Newtown, PA and Pennington, NJ.

13 Dec 2011

Basque engineer develops computer-based psychological tool for sportsperson

Teskal is a computing application designed to relieve 'the loneliness of the sportsperson'. The better a sportsperson is, the more time he or she spends away from home, and few can afford the luxury of travelling with psychologists, coaches, etc.

13 Dec 2011

U.S. acting to link GBV, HIV efforts

In this post in the U.S. Department of State's "DipNote" blog, U.S. Global AIDS Coordinator Ambassador Eric Goosby and Melanne Verveer, ambassador-at-large for global women's issues, report on the relationship between gender-based violence (GBV) and HIV.

13 Dec 2011

Drug users with HIV infection have 74% higher risk of overdose

A study from Rhode Island Hospital is the first to systematically review and analyze the literature on the association between HIV infection and overdose risk.

13 Dec 2011

Iowa: GOP presidential debate turns up campaign heat

With the Iowa caucuses fast approaching, new political ads are hitting the airwaves, and Saturday night's debate draws lots of fact-checking by news organzations.

13 Dec 2011

Fred Kavli Public Symposium discusses about 'The Brain on Trial'

How should insights about the brain affect the course of a criminal trial, from the arguments in a courtroom to the issuing of a sentence?

13 Dec 2011

Lawmakers move closer to completing legislative to-do list

Still remaining on the list, however, is action to prevent a scheduled reduction in Medicare payments for physicians. A proposal to avert this cut is included in a broader measure that would extend the payroll tax break.

13 Dec 2011

Study demonstrates that bone marrow and PBSC result in similar patient survival

Patients who receive a blood stem cell transplant from a donor outside of their family to treat leukemia and other blood diseases are more likely to have graft failure but less likely to experience graft-versus-host disease if the transplanted blood cells come directly from a donor's bone marrow, rather than from circulating peripheral blood stem cells (PBSCs), according to new research.

13 Dec 2011

Reuters examines maternal mortality in Afghanistan

"An Afghan woman can expect to have an average 5.1 babies in her lifetime, the highest fertility rate in Asia," Reuters writes in the first of two articles examining childbirth and maternal mortality in Afghanistan. The news service adds that "giving birth a common, and frequent experience -- but mothers say it is too often also hard, lonely and frightening."

13 Dec 2011

Incyte announces further analyses from Jakafi Phase III trial on myelofibrosis

Incyte Corporation today announced that further analyses from the global, pivotal Phase III clinical program of Jakafi (ruxolitinib or INC424) are being presented at the 2011 American Society of Hematology (ASH) Annual Meeting.

13 Dec 2011

Fla. squeezes Medicaid spending; Colo. dispute threatens budget

Republican Gov. Rick Scott this week proposed to slash Florida's spending in the joint state-federal health insurance program for the poor by $2 billion, in part to add $1 billion to education in the next fiscal year.

13 Dec 2011