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S*BIO announces results from pacritinib Phase 2 study on myelofibrosis

S*BIO Pte Ltd today announced that results from a Phase 2 study demonstrated that its JAK2 inhibitor pacritinib (SB1518) effectively reduced splenomegaly in myelofibrosis (MF) patients, with minimal impact on existing cytopenias providing an important therapeutic niche in the treatment of MF. Results were presented at the 53rd ASH Annual Meeting and Exposition in San Diego.

13 Dec 2011

Pulitzer Center announces launch of collaborative reproductive health reporting project

The Pulitzer Center on Crisis Reporting "launched its collaborative reproductive health reporting project last week at the International Family Planning Conference (IFPC) in Dakar, Senegal," according to a post on the Center's website.

13 Dec 2011

WPI to develop smart phone app for foot ulcers, advanced diabetes

An interdisciplinary research team at Worcester Polytechnic Institute (WPI) has received a $1.2 million award from the National Science Foundation to develop a smart phone application that will help people with advanced diabetes and foot ulcers better manage their disease.

13 Dec 2011

'Twinning' team approach improves pediatric lymphoma outcomes

In an African county lacking any specialists in children's cancers, a team approach that "twins" Rwandan physicians with Boston-based pediatric oncologists has shown it can deliver expert, curative care to young patients stricken with lymphoma.

13 Dec 2011

Combination of bortezomib and panobinostat shows promise against advanced MM

When the targeted drug bortezomib stops working in patients with advanced multiple myeloma, the patients survive only an average of five months longer. But a phase 2 clinical trial has shown that pairing bortezomib with an experimental drug, panobinostat, may be a promising new treatment for such patients, Dana-Farber Cancer Institute researchers say.

13 Dec 2011

Scientists create antigenic myeloma peptide 'cocktail'

Scientists at Dana-Farber Cancer Institute have created a "cocktail" of immune-stimulating peptides they believe could provoke the body's defenses to attack multiple myeloma in its early "smoldering" phase and slow or prevent the blood cancer.

13 Dec 2011

House 'doc fix' proposal provides temporary relief to physicians, draws hospital concern

The "payment patch" would largely be paid for by charging higher Medicare premiums to affluent seniors and by cutting hospital payments.

13 Dec 2011

Synta's ganetespib shows potent in vitro and in vivo activity against multiple breast cancer types

Synta Pharmaceuticals Corp. Ganetespib shows potent in vitro and in vivo activity against multiple types of breast cancer including HER2-positive, ER/PR positive, triple-negative, and inflammatory breast cancer according to results presented at the San Antonio Breast Cancer Symposium.

13 Dec 2011

Inaccurate blood pressure assessment may impact hypertension treatment decisions

Because some clinicians fail to stick to official recommendations for blood pressure monitoring, a number of patients are misclassified, which could have an impact on decisions about their treatment. According to Gretchen Ray and colleagues, from the University of New Mexico College of Pharmacy, when routine blood pressure monitoring in clinics is compared with measurements based on the latest guidelines, 93 percent of patients have different blood pressure readings.

13 Dec 2011

Study describes new method that synthesizes novel anti-HIV protein

The most abundant and important molecules in all living organisms are proteins; after all they manage to participate in every single one of life's essential reactions. So it is easy to see why scientists have been making such a fuss trying to learn how to synthesise them in laboratory as this would provide them with a tool of extraordinary potential. Unfortunately, this has not proved easy.

13 Dec 2011

U of A creates 'conversation cards' for pediatric weight management

Medical researchers at the University of Alberta have created a deck of cards with conversation starters about sensitive and informational topics related to weight, that parents can use to guide their discussions when talking about their child's weight management with health professionals.

13 Dec 2011

Globe and Mail reports on potential factors leading to increasing HIV incidence in Uganda

After experiencing a decline in the number of new HIV infections in the 1990s, Uganda's "HIV incidence rate is creeping back up again. New infections are increasing, and the sense of urgency has vanished," the Globe and Mail reports.

13 Dec 2011

LTCRT participates in GPS study that seeks to personalize cancer care

The Lawson Translational Cancer Research Team (LTCRT) of the Lawson Health Research Institute is one of five groups participating in a new study that seeks to personalize cancer drug treatment.

13 Dec 2011

Higher individual doses of radiotherapy safe for men with prostate cancer

Less overall radiotherapy, delivered in fewer but higher doses, is as safe as standard, lower doses for treating prostate cancer, according to new research* published in the Lancet Oncology.

13 Dec 2011

Single rooms in hospitals is not enough to prevent gastroenteritis

To offer patients single rooms in hospitals is not enough to prevent gastroenteritis. That is shown in a master thesis at Nordic School of Public Health NHV.

13 Dec 2011

NIH, Autism Speaks announce addition of AGRE as data federation site for NDAR

Autism Speaks - North America's largest autism science and advocacy organization - joins the National Institutes of Health (NIH) in announcing the addition of Autism Speaks Autism Genetic Resource Exchange (AGRE) as a data federation site for the National Database for Autism Research (NDAR). The addition of AGRE data will help create the largest multidisciplinary source of autism research data to date.

13 Dec 2011

USAID administrator urges journalists to cover important world issues, including global health

"Journalists have a responsibility to cover important world issues and stories, urged Dr. Rajiv Shah, administrator of USAID, while speaking at an event at Harvard University on Thursday evening," GlobalPost reports.

13 Dec 2011

Study to establish zebrafish as functional animal model for V. cholerae

A small fish may prove useful to understanding a worldwide health problem, if a Wayne State University researcher is correct.

13 Dec 2011

Quintiles launches Kun Tuo to service unique needs of biopharma companies in China

Further deepening its commitment to China, Quintiles today announced the launch of Kun Tuo, a local contract research organization (CRO) built to service the unique needs of the Chinese biopharmaceutical industry and multinational biopharma companies operating in China.

13 Dec 2011

Supply chain map could help improve access to anti-malarial drugs

The problems of archaic logistics infrastructure, inefficient distribution channels and disruptive black markets must all be addressed urgently if Africa is to cope with the growing problem of malaria, according to a study published in the International Journal of Logistics Systems and Management.

13 Dec 2011