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NIH-led study advances HIV vaccine research

HIV is coated in sugars that usually hide the virus from the immune system. Newly published research reveals how one broadly neutralizing HIV antibody actually uses part of the sugary cloak to help bind to the virus. The antibody binding site, called the V1/V2 region, represents a suitable HIV vaccine target, according to the scientists who conducted the study. In addition, their research reveals the detailed structure of the V1/V2 region, the last part of the virus surface to be visualized at the atomic level.

24 Nov 2011

Interview with AIDS economist Mead Over

ONE member Erin Hohlfelder presents excerpts of an interview she conducted with AIDS economist Mead Over in this ONE blog post. Over discusses his new book, titled "Achieving an AIDS Transition: Preventing Infections to Sustain Treatment," AIDS program financing, government roles, and creating incentives for HIV prevention program success.

24 Nov 2011

Scientists discover genetic mechanism behind finger malformation

Scientists from the EPFL and the University of Geneva have discovered a genetic mechanism that defines the shape of our members in which, surprisingly, genes play only a secondary role. The research published in Cell, online the 23rd of November, shows the mechanism is found in a DNA sequence that was thought, incorrectly, to play no role.

24 Nov 2011

Merck agrees to pay $950 million in Vioxx settlement

The pharmaceutical giant will pay a $321 million criminal fine and a $628 million civil settlement.

24 Nov 2011

People eating out of home consume more calories and fat, less micronutrients

Eating out of home means you run a fair chance of ingesting more calories and fat, and less micronutrients like vitamin C, iron and calcium. And people nowadays eat more out of house, also in developing countries. So conclude scientists from the Antwerp Institute of Tropical Medicine, upon reviewing more than seven thousand studies. They report in the journal Obesity Reviews.

24 Nov 2011

House panel seeks records about Kagan and health law

House Judiciary Committee Chairman Lamar Smith (R-Texas) on Tuesday asked the Obama administration to provide documents and internal correspondence on Supreme Court Justice Elena Kagan's role in defense of the health reform law. Republicans argue that Kagan, while she was solicitor general in the Obama administration, participated in the early defense of the law and should recuse herself as the law goes before the Supreme Court.

24 Nov 2011

Transplantation of tissue-engineered windpipe can benefit patients with tracheal cancer

Tracheal tumors can be surgically removed, but most are too large for the surgery to be successful by the time they are discovered. Therefore, new therapeutic options are needed. Even in patients with operable tumors, the proportion of complete tumor resection is less than 60%. This outcome would be greatly improved if a trachea substitute with similar anatomical, physiological and biomechanical properties of the patient's original trachea were available.

24 Nov 2011

Democrats ask Obama not to dilute contraceptive benefits

Democratic lawmakers, fearful that President Obama is on the verge of significantly diluting a proposed regulation that would give millions of women access to birth control without out-of-pocket insurance charges, are furiously lobbying the White House to hold the line.

24 Nov 2011

Nocturnal temperature controlled laminar airflow treatment for atopic asthma

A simple device that filters out airborne asthma triggers during sleep can ease persistent symptoms of the condition during the day and improve quality of life, suggests research published online in Thorax.

24 Nov 2011

Congress facing deadline on Medicare payments to doctors

Preventing the cut in Medicare payments to doctors is estimated to cost more than $20 billion next year. It is considered a near certainty that Congress will address it because of the clout that Medicare and doctors have with lawmakers. Within minutes of Monday's announcement that the supercommittee had failed, the American Medical Association was warning that the 27 percent cut would "force many physicians to limit the number of Medicare and TRICARE patients they can care for in their practices."

24 Nov 2011

Study raises concerns about Bisphenol A in canned foods

A recent study published in JAMA raises concerns about Bisphenol A (BPA) in canned foods.

24 Nov 2011

Community-based program battles gender-based violence

Hillary Anderson, a communications intern for Management Sciences for Health (MSH), writes in this post on MSH's "Global Health Impact" blog about the organization's Community-based Family Planning and HIV & AIDS Services (CFPHS) project, which "worked to address gender-based violence (GBV) in Malawi through behavior change communication (BCC) activities."

24 Nov 2011

No variation in mortality by timing of operation

The timing of surgical procedures—afternoon versus morning or Friday versus Monday—doesn't affect the risk of death after surgery, concludes a study in the December issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

24 Nov 2011

Why foreign aid should matter to GOP presidential candidates

"I suggest that GOP presidential candidates apply similar personal finance principles to evaluate why foreign aid is worth the investment," Samuel Worthington, president of InterAction, writes in a CNN opinion piece.

24 Nov 2011

Novel genetic sequencing methods identify various bacteria on public restrooms

Everyone wonders what bugs might be lurking in public bathrooms. Now researchers are using novel genetic sequencing methods to answer this question, revealing a plethora of bacteria all around, from the doors and the floors to the faucet handles and toilet seats, with potential public health implications, as reported Nov. 23 in the online journal PLoS ONE.

24 Nov 2011

Obama should announce scale-up of AIDS treatment programs

Secretary of State Hillary Clinton's recent speech calling for an "AIDS-free generation" through the use of multiple prevention strategies, including more widespread antiretroviral therapy, "was a dramatic reversal of U.S. policy, which has historically viewed treatment more as a costly expense rather than our most powerful prevention investment," physician Loretta Ciraldo and Katrina Ciraldo, a student at Boston University School of Medicine, write in this Miami Herald opinion piece.

24 Nov 2011

First systematic and in-depth analysis of cardiac arrest in hospital

Only a few decades ago, sudden cardiac arrest was a death sentence. Today, a victim of sudden cardiac arrest is saved roughly once every six hours in Sweden, reveals a thesis from the Sahlgrenska Academy at the University of Gothenburg, Sweden, reviewing all cases of sudden cardiac arrest over a 30-year period.

24 Nov 2011

Insurance commissioners back brokers on health law standard

After more than a year of debate, state regulators ... approved a resolution calling for changes to the healthcare reform law's medical loss ratio provision. The National Association of Insurance Commissioners (NAIC) passed the measure 26-20, over strenuous objections from commissioners who said the process and the resolution itself would undermine the NAIC's reputation.

24 Nov 2011

Study looks at effects of antipsychotic drugs on two brain receptors linked to schizophrenia

Researchers from Mount Sinai School of Medicine, have identified the pattern of cell signaling induced by antipsychotic drugs in a complex composed of two brain receptors linked to schizophrenia.

24 Nov 2011

OECD report finds U.S. pays more by far for health care

The U.S. healthcare system is more effective at delivering high costs than quality care, according to a new study that found first-rate treatment for cancer but insufficient primary care for other ailments. The study, released on Wednesday by the 34-nation Organization for Economic Cooperation and Development, or OECD, said Americans pay more than $7,900 per person for healthcare each year -- far more than any other OECD country -- but still die earlier than their peers in the industrialized world.

24 Nov 2011