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Two ALS-associated genes work in tandem to support long-term survival of motor neurons

Although several genes have been linked to amyotrophic lateral sclerosis (ALS), it is still unknown how they cause this progressive neurodegenerative disease. In a new study, Columbia University Medical Center (CUMC) researchers have demonstrated that two ALS-associated genes work in tandem to support the long-term survival of motor neurons.

2 Sep 2011

Dendritic cells play central role in regulation of acetaminophen's toxicity

NYU School of Medicine researchers have discovered that dendritic cells in the liver have a protective role against the toxicity of acetaminophen, the widely used over-the-counter pain reliever and fever reducer for adults and children.

2 Sep 2011

Fibrous stroma can help predict aggressiveness of squamous cell carcinoma

The nature of the connective tissue surrounding lung cancer nests can help predict the aggressiveness of squamous cell carcinoma, according to research published in the September issue of the Journal of Thoracic Oncology, the official publication of the International Association for the Study of Lung Cancer.

2 Sep 2011

Roundup: New health center money in Ill.; groups question insurers on discrimination in Fla.

Gov. Pat Quinn continued his ribbon-cutting spree today, announcing the state will spend $30.5 million to build and renovate 14 health centers across the state that provide care for low-income patients.

2 Sep 2011

Increased fat mass linked to high-intensity back pain

Increased back pain among people who are overweight or obese is specifically related to increased body fat content, reports a study in the September 15 issue of Spine.

2 Sep 2011

Stomach acid-reducing drugs appear to cause small intestine damage

Patients often take drugs to lower stomach acid and reduce the chances they will develop ulcers from taking their anti-inflammatory drugs for conditions such as arthritis, but the combination may be causing major problems for their small intestines, McMaster researchers have found.

2 Sep 2011

CRI announces winners of 2011 Coley Award for distinguished research in tumor immunology

The Cancer Research Institute, Inc. (CRI), a U.S. nonprofit organization established in 1953 to advance the science of tumor immunology and drive the discovery of new cancer immunotherapies, announced today the winners of the 2011 William B. Coley Award for Distinguished Research in Tumor Immunology.

2 Sep 2011

New clinical data on Bristol-Myers Squibb's NULOJIX to be presented at ESOT 2011 congress

Bristol-Myers Squibb Company today announced that new data on NULOJIX (belatacept) will be presented at the European Society for Organ Transplantation (ESOT) Congress on September 4 -7, 2011 in Glasgow, Scotland, United Kingdom.

2 Sep 2011

Integrating rapid syphilis and HIV testing for pregnant women could reduce maternal, child morbidity and mortality

"A study conducted in Uganda and Zambia by the Elizabeth Glaser Pediatric AIDS Foundation (EGPAF) found high rates of syphilis and HIV co-infection among pregnant women in both countries," but showed that "integrating rapid syphilis screening and HIV testing for pregnant women was feasible, cost-effective, and helped to prevent transmission of syphilis and HIV from mother-to-child," PlusNews reports.

2 Sep 2011

Age-related lens yellowing linked to sleep disorders

A natural yellowing of the eye lens that absorbs blue light has been linked to sleep disorders in a group of test volunteers, according to a study in the September 1 issue of the journal Sleep. As this type of lens discoloration worsened with age, so did the risk of insomnia.

2 Sep 2011

Insight into molecular basis of Enhanced S-Cone Syndrome

A new research report published in The FASEB Journal will help ophthalmologists and scientists better understand a rare genetic disease that causes increased susceptibility to blue light, night blindness, and decreased vision called Enhanced S-Cone Syndrome or Goldman-Favre Syndrome.

2 Sep 2011

UTHealth to study BMS-820836 in Phase II trial for major depressive disorder

A new medication to treat major depressive disorder in patients who have not responded to other antidepressants is being studied in a Phase II clinical trial by researchers at The University of Texas Health Science Center at Houston.

2 Sep 2011

Medtronic initiates U.S. post-approval study of Endurant AAA Stent Graft System

Leading the development of endovascular aortic repair (EVAR), Medtronic, Inc. today announced the start of its U.S. post-approval study of the Endurant AAA Stent Graft System, a medical device used to treat abdominal aortic aneurysms.

From Medtronic 2 Sep 2011

Tobacco industry goes after confidential smoking data from UK’s Department of Health

The tobacco giants are urging the UK’s Department of Health to extract information about meetings between government officials and researchers who are investigating the public-health implications of new smoking policies.

2 Sep 2011

Eclipse extends tender offer to acquire Icagen for $6.00 per share

Pfizer Inc. and Icagen, Inc. announced today that Pfizer's wholly-owned subsidiary, Eclipse Acquisition Corp., has extended the expiration date of its tender offer for all outstanding shares of common stock of Icagen for $6.00 per share, paid to the seller in cash, without interest thereon, less any applicable withholding and transfer taxes.

2 Sep 2011

Low-cost, portable technique can detect specific proteins in human blood

Blood tests are important diagnostic tools. They accurately tease-out vanishingly small concentrations of proteins and other molecules that help give a picture of overall health or signal the presence of specific diseases. Current testing procedures, however, are expensive and time-consuming, while sophisticated test equipment is bulky and difficult to transport.

2 Sep 2011

HIV/AIDS policies “woefully inadequate” in Britain: Report

AIDS and HIV prevention policies in Britain are “woefully inadequate” and must be improved, a House of Lords committee warned today. The report by the Lord Select Committee is published on the 25th anniversary of the 'Don't Die of Ignorance' campaign, a public health initiative launched to try to stem the spread of the virus.

2 Sep 2011

Engineered virus shows promise in cancer therapy via bloodstream

Scientists have engineered a virus that when injected into the blood, can selectively target cancer cells throughout the body. The virus attacked only tumours, leaving the healthy tissue alone, in a small trial on 23 patients, according to the journal Nature.

2 Sep 2011

LCA applauds FDA approval of Xalkori for ALK positive non-small cell lung cancer

Lung Cancer Alliance (LCA) applauds the Food and Drug Administration (FDA) approval of Xalkori (crizotinib) with non-small cell lung cancer (NSCLC) who are ALK positive. The drug was approved based on data from two clinical trials, both of which showed a significant increase in overall survival.

2 Sep 2011

Tamiflu resistant flu found in Newcastle, Australia

The influenza pandemic has gathered a lot of action, advice and coverage over the last few years. In 2009, an international H1N1 influenza pandemic led to concerns that there would be a repeat of the 1918 influenza pandemic which resulted in millions of deaths worldwide. The World Health Organization recorded over 37,000 cases of the H1N1 pandemic influenza in Australia and 193 confirmed deaths.

2 Sep 2011