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FDA issues Refusal to File letter for Eisai's perampanel NDA to treat partial-onset seizures

Eisai Inc. announced today that the U.S. Food and Drug Administration (FDA) has issued a Refusal to File letter in response to the company's New Drug Application (NDA) for perampanel (E2007), an investigational drug, for the treatment of partial-onset seizures associated with epilepsy which was submitted in May 2011.

29 Jul 2011

Cancer Research UK honors cell signalling expert with Lifetime Achievement Prize

Professor Chris Marshall has been named as the recipient of this year's Cancer Research UK Lifetime Achievement Prize.

29 Jul 2011

Stateline: Detailing how a Medicaid 'blended rate' plan would work

House Republicans already have voted to convert Medicaid into a block grant program. ... The Obama administration has issued its alternative — a plan to cut $100 billion from federal Medicaid spending over the next decade.

29 Jul 2011

BTI's IPOXYN data on traumatic shock and ischemia to be presented at XIIIth MGH symposium

Boston Therapeutics, Inc., a public company registered with the SEC and a developer of diabetes therapeutics, announced today that experiments performed in the laboratory of Massachusetts General Hospital (MGH) faculty member Warren M. Zapol, MD, Emeritus Anesthetist-in-Chief and Director of the MGH Anesthesia Center for Critical Care Research, on BTI's new oxygen carrier for traumatic shock and ischemia, IPOXYNTM, will be presented at the "XIII International Symposium on Blood Substitutes and Oxygen Therapeutics" to be held July 27th-29th at MGH.

29 Jul 2011

Introducing maspin protein into tumor nucleus can stop growth and spread of cancer

According to the Canadian Cancer Society, one in four Canadians will die of cancer. This year alone, the disease will kill an estimated 75,000 people. With incidence rates on the rise, more cancer patients are facing grave prognoses.

29 Jul 2011

NCI awards Hutchinson Center to coordinate cancer and obesity consortium

The National Cancer Institute has awarded $8.2 million over the next five years to Fred Hutchinson Cancer Research Center to extend its role as the coordinating hub of a nationwide research consortium that aims to better understand the link between obesity and cancer.

29 Jul 2011

Scientist discovers novel way to convert human skin cells into neurons

A scientist at the Gladstone Institutes has discovered a novel way to convert human skin cells into brain cells, advancing medicine and human health by offering new hope for regenerative medicine and personalized drug discovery and development.

29 Jul 2011

Tips to make family vacations less hazardous for kids and parents

Family vacations live in infamy. Sometimes it's for the lasting memories of family bonding and new wonders experienced together, and sometimes for the horrors of just trying to get to a destination.

29 Jul 2011

Longer looks: Expensive cities for health care; mapping Medicaid

It's bewildering for anyone who has ever paid for a health procedure out of pocket when health insurance doesn't cover the full cost: Why does health care cost the way it does, and why do the costs fluctuate depending on where you go and who you see? A colonoscopy, for example, can range from $500 to $3,000 — a large difference depending on how health insurance providers negotiate rates.

29 Jul 2011

Polaris initiates ADI-PEG 20 Phase 3 trial in hepatocellular carcinoma

Polaris Group today announced that it has dosed the first patient in a pivotal Phase 3 clinical trial evaluating its lead cancer therapeutic, pegylated arginine deiminase (ADI-PEG 20), in hepatocellular carcinoma (HCC) patients.

29 Jul 2011

Patients with diabetes, depression more likely to develop serious eye disease

Patients with diabetes who also suffer from depression are more likely to develop a serious complication known as diabetic retinopathy, a disease that damages the eye's retina, a five-year study finds.

29 Jul 2011

Routine dipstick urine test may identify individuals with silent kidney disease

A simple and inexpensive urine test routinely done in family doctors' offices may be the key to identifying individuals who are silently undergoing rapid kidney function decline, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology.

29 Jul 2011

LUMC recognized as one of the nation's Most Wired Hospitals and Health Systems

Loyola University Medical Center (LUMC) has been named one of the nation's Most Wired Hospitals and Health Systems, according to results of the 2011 Most Wired Survey and Benchmarking Study.

29 Jul 2011

State roundup: Mass. communities look to new law for health savings

Area cities and towns are salivating at the prospect of saving millions of dollars in insurance costs in coming years, under a new law making it easier to change health coverage for their employees.

29 Jul 2011

Sigma-Tau, Soligenix expand partnership to develop and commercialize orBec in Europe

Soligenix, Inc., a late-stage biopharmaceutical company, announces the expansion and amendment of its North American licensing partnership with Sigma-Tau Pharmaceuticals, Inc. for the development and commercialization of orBec into the European territory.

29 Jul 2011