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First presentation of anti-HER2 antibody-drug conjugate as first-line therapy for advanced breast cancer

A new type of breast cancer treatment has shown encouraging activity as a first-line therapy in HER2-positive metastatic disease, researchers reported at the 35th Congress of the European Society for Medical Oncology (ESMO) in Milan, Italy.

12 Oct 2010

Scripps Research study findings could transform drug development to produce more effective treatments

Scientists from The Scripps Research Institute have uncovered new evidence that challenges the current theory about a process key to the way modern drugs are designed and how they work in the human body.

12 Oct 2010

Researchers develop new method to identify chemical histone modifications

Test system on Drosophila should provide the key to histone function. The genetic inherited material DNA was long viewed as the sole bearer of hereditary information. The function of its packaging proteins, the histones, was believed to be exclusively structural. Additional genetic information can be stored, however, and passed on to subsequent generations through chemical changes in the DNA or histones. Scientists from the Max Planck Institute for Biophysical Chemistry in Göttingen have succeeded in creating an experimental system for testing the function of such chemical histone modifications and their influence on the organism.

12 Oct 2010

ImmunoGen announces updated fiscal 2011 guidance

ImmunoGen, Inc., a biotechnology company that develops targeted antibody-based anticancer products, today announced updated guidance for the Company's fiscal year ending June 30, 2011.

12 Oct 2010

Challenges in provision of high-quality health care at end of life

Health care in the last six months of life has become progressively more expensive for patients with heart failure both among Medicare beneficiaries in the United States and older adults in Canada, with a high rate of hospitalizations in the final six months of life in both countries, according to two reports posted online today that will be published in the February 14 print issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

12 Oct 2010

WHO Western Pacific meeting to address maternal health, rise in dengue

Maternal health and dengue fever are among the issues that will be discussed at the 61st session of the WHO Regional Committee for the Western Pacific, Bernama reports.

12 Oct 2010

Behavioral management and preventive medication can combat migraine: Research

The combination of preventive medication and behavioral changes offered significant relief for 77 percent of the individuals enrolled in a study aimed at combating frequent, disabling migraine headaches, according to new Ohio University research published this week in the British Medical Journal.

12 Oct 2010

Albireo reports positive results from A3309 Phase IIb study in chronic idiopathic constipation

Albireo today announced positive top-line results from a Phase IIb study in chronic idiopathic constipation (CIC) assessing efficacy and safety of three different dose levels (5, 10 and 15 mg orally once a day) of the investigational drug A3309 during an eight week trial. Analyses of the data show clinically meaningful and statistically significant improvement for patients treated with A3309 compared to placebo-treated patients.

12 Oct 2010

GlobalSMS platform selected to increase breastfeeding rates among new mothers

CellTrust Corporation, the world's largest provider of SecureSMS(Secure SMS) for mobile phones announced today that its GlobalSMS platform solution has been selected by the Queensland University of Technology (QUT), for the world's first text message pilot program to offer breastfeeding support for new mothers in Australia.

12 Oct 2010

Scolisoft database helps surgeons to improve scoliosis treatment

The adolescent and teen years can be tough enough without the disfiguring and activity-limiting effects of scoliosis. 18-year-old William Burnley knows this well. His diagnosis of scoliosis came after he couldn't properly execute directions from his Tae Kwon Do instructor.

12 Oct 2010

Healthy lifestyle can reduce breast cancer risk in women with family history

Having a family history of breast cancer can lead some people to wonder if their risk is out of their control. However, a study of more than 85,000 postmenopausal women observed that regular physical activity, maintaining a healthy weight, and drinking less alcohol lowers breast cancer risk for women with, and without a family history of the disease.

12 Oct 2010

Specialized bacterial filaments shown to conduct electricity

Some bacteria grow electrical hair that lets them link up in big biological circuits, according to a University of Southern California biophysicist and his collaborators.

12 Oct 2010

Helix completes GLP toxicology study milestone in L-DOS47 development program

Helix BioPharma Corp. today announced that it has completed its definitive GLP, rodent and primate, repeat-dose toxicology studies with L-DOS47. These studies demonstrated a good safety profile in an expanded number of rodent and primate test animals, building upon Helix's positive findings from its preliminary non-GLP toxicology studies.

12 Oct 2010

Most men with prostate cancer not referred to hospice care early enough

More than half of men dying of prostate cancer use hospice care - a significant increase over the last two decades - but most wait too long to enroll so they can't take full advantage of the palliative care that could make their deaths easier, a study by researchers at UCLA's Jonsson Comprehensive Cancer Center found.

12 Oct 2010

Soldier suicides still high depite Army's prevention program

The New York Times reports that "nearly 20 months after the Army began strengthening its suicide prevention program and working to remove the stigma attached to seeking psychological counseling, the suicide rate among active service members remains high and shows little sign of improvement.

12 Oct 2010

Study finds no link between AMD treatments and increase in cardiovascular complication

Newer treatments for age-related macular degeneration (AMD)-including an intravitreous (into the eye) injection of a chemotherapy drug and use of a related compound approved for use against the eye disease-do not appear to be associated with an increased risk of cardiovascular complications or death when compared with existing therapies, according to a report in the October issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

12 Oct 2010

Covidien presents hernia and abdominal wall repair products at EHS Meeting

Covidien, a leading global provider of healthcare products, announced that its hernia and abdominal wall repair products were featured in 18 podium presentations at the 32nd International Congress of the European Hernia Society (EHS).

12 Oct 2010

Committee on World Food Security meeting begins in Rome

A high-level meeting of the U.N. Food and Agriculture Organization's (FAO) Committee on World Food Security aimed at addressing food insecurity, price rises and the purchase of large amounts of agricultural land in developing countries started in Rome on Monday, Agence France-Presse/Capital FM reports.

12 Oct 2010

Physical and psychological factors contribute to somatic symptoms: Report

Patients with cancer who experience pain or depression also have a high rate of physical symptoms, such as fatigue, dry mouth and nausea, according to a report in the October 11 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

12 Oct 2010

New combination technique improves study of protein characterization

Using a combination of high-powered computers and advanced experimental magnetic resonance data, a Florida State University biophysical chemist has developed techniques that improve the way scientists can study and predict the structure and dynamics of proteins found in the human body. His innovations could ultimately shorten the time it takes researchers to develop new, more effective drugs and better understand biomedical processes that underlie a variety of health conditions.

12 Oct 2010