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Ajinomoto AminoScience introduces new resource for peptides

Ajinomoto AminoScience, LLC announced today the launch of AjiPhase™, an evolution of liquid phase peptide synthesis containing the benefits of solid and liquid phase methodologies. This new service is designed as an innovative tool that will enable pharmaceutical companies to expand their development pipeline and provide a uniform production process through the entire development lifecycle.

21 Apr 2010

Positive preclinical pharmacokinetic data for XMT-1001 presented at AACR 2010

Mersana Therapeutics, a platform-based cancer therapeutics company, announced today positive preclinical pharmacokinetic data for its lead development candidate, XMT-1001, which is currently in a Phase 1 clinical trial in patients with advanced solid tumors. The results were presented in a poster session at the AACR 101st Annual Meeting 2010 in Washington, DC, held April 17-21, 2010.

21 Apr 2010

Initial results of gallium-containing compound to treat serious infection presented at AACR 2010

Genta Incorporated today announced the presentation of initial results from the first human use of a gallium-containing compound to treat serious infection. In a patient with cystic fibrosis and a highly resistant lung infection, who has been treated over a 2-year period, high concentrations of gallium were achieved in sputum.

21 Apr 2010

Immunomedics' blood assay for PAM4-protein can detect pancreatic cancer and predict early relapse

Immunomedics, Inc., a biopharmaceutical company focused on developing monoclonal antibodies to treat cancer and other serious diseases, today reported that a new blood test using the Company's proprietary humanized antibody, clivatuzumab or PAM4, predicted a partial response in an initial set of patients treated with a combination of the antibody labeled with yttrium-90 (Y-90) and gemcitabine. Results were presented at the 101st Annual Meeting of the American Association for Cancer Research.

21 Apr 2010

Receiving cochlear implant before 18 months of age improves child's ability to hear: Study

Receiving a cochlear implant before 18 months of age dramatically improves a deaf child's ability to hear, understand and, eventually, speak, according to a multicenter study led by scientists at Johns Hopkins.

21 Apr 2010

ARIAD presents AP26113 investigational ALK inhibitor preclinical study data at AACR annual meeting

ARIAD Pharmaceuticals, Inc. today announced results of preclinical studies on its investigational anaplastic lymphoma kinase (ALK) inhibitor - AP26113 - showing potent inhibition of the target protein and of mutant forms that are resistant to the first-generation ALK inhibitor, which currently is in clinical trials in patients with cancer. ARIAD scientists presented these data today at the annual meeting of the American Association for Cancer Research (AACR) in Washington, D.C.

21 Apr 2010

Drugmakers raised prices last year in anticipation of new health law, Eli Lilly reports financial hit

"Drug companies sharply raised prices last year, ahead of increased rebates they must pay to Medicaid and other expenses tied to the federal health overhaul passed last month. Prices for brand-name pharmaceuticals rose 9.1% last year, the biggest increase in at least a decade, according to pharmacy-benefit manager Express Scripts Inc."

21 Apr 2010

CVS Caremark survey results of specialty pharmacy patients

CVS Caremark today announced results of a survey of the company's specialty pharmacy patients that provides insights into their views on medication adherence and their perceptions about the role of their specialty pharmacy. The survey results show nearly 70 percent of respondents believe their specialty pharmacy team played an important role in encouraging them to take their specialty medications as prescribed.

21 Apr 2010

Immunomedics reports study results of antibody-SN-38 conjugates for targeted cancer chemotherapy

Immunomedics, Inc., a biopharmaceutical company focused on developing monoclonal antibodies to treat cancer and other serious diseases, reported today at the 101st Annual Meeting of the American Association for Cancer Research (AACR) results from two studies aimed at improving the design of antibody-SN-38 conjugates for targeted cancer chemotherapy.

21 Apr 2010

AACN joins national, state and community organizations in support of NHDD

Because critical care nurses are often among those caring for patients during their final days, the American Association of Critical-Care Nurses joins national, state and community organizations in support of the third annual National Healthcare Decisions Day on Friday, April 16, 2010.

21 Apr 2010

EGFR levels may help early detection of breast cancer

Levels of epidermal growth factor receptor (EGFR) may be elevated in the blood of women within 17 months prior to their breast cancer diagnosis, according to findings presented at the American Association for Cancer Research 101st Annual Meeting 2010, held here April 17-21.

21 Apr 2010

Preclinical data in neuroblastoma for perifosine to be presented at AACR 2010 Meeting

Aeterna Zentaris Inc., a late-stage drug development company specialized in oncology and endocrine therapy, today announced that preclinical data in neuroblastoma for perifosine, the Company's novel, potentially first-in-class, oral anti-cancer agent that inhibits Akt activation in the phosphoinositide 3-kinase pathway, will be presented at the 101st Annual Meeting of the American Association for Cancer Research, currently being held at the Walter E. Washington Convention Center in Washington, DC.

21 Apr 2010

Researchers demonstrate role of HSP-90 in portal hypertension

Neural vasoregulation represents a rapid and potent mode of altering vascular tone but has not been investigated thoroughly during portal hypertension. Heat shock protein-90 is well-known to act as a molecular chaperone optimizing endothelial and neural NO-synthase enzyme activity and thus, NO production.

21 Apr 2010

Concateno bestowed Queen's Award for Enterprise

Concateno (>Europe's leading drug and alcohol test provider, has been awarded the prestigious Queen's Award for Enterprise (http://www.queensawards.org.uk/business/business.html ) in recognition of its outstanding innovation and commercial performance.

21 Apr 2010

Study investigates potential long-term effects of maternal stature on offspring mortality

Among 54 low- to middle-income countries, a mother's shorter height is associated with a higher rate of death for her children and a greater likelihood of these children being underweight and having a reduced rate of growth, according to a study in the April 21 issue of JAMA.

21 Apr 2010

A*STAR's BMRC and SIgN award grants for twelve research projects on infectious diseases and immunology

Twelve research projects on infectious diseases and immunology have been awarded grants by A*STAR's Biomedical Research Council (BMRC) and Singapore Immunology Network (SIgN) this year.

21 Apr 2010

LDR completes IDE study on Mobi-C cervical artificial disc

LDR, a privately held company with innovative spinal implants for non-fusion and fusion applications, announced completion of the 24-month follow-up phase of its two-level IDE study on the Mobi-C cervical artificial disc. Having previously finalized the 24-month follow-up phase of the one-level study earlier this year, LDR is now the first company to fully enroll and reach two-year follow-up on a concurrent one-level and two-level cervical artificial disc replacement study.

21 Apr 2010

Findings may illuminate how cancer forms and migrates

Rho proteins have been described as "molecular switches" and play a role in cell migration, cell proliferation, cell death, gene expression, and multiple other common cellular functions.

21 Apr 2010

MMRC Multiple Myeloma Genomics Initiative presented at AACR 2010

An analysis of 38 myeloma tumor genomes surveyed through extensive next-generation sequencing by the Broad Institute has revealed intriguing recurrent mutations that point to important cellular pathways which contribute to multiple myeloma. These data were revealed during an oral presentation entitled "First Impressions of the Multiple Myeloma Genome" by Todd R. Golub, MD, Director of the Cancer Program at the Eli and Edythe L. Broad Institute.

21 Apr 2010

Tea for Teal event raises $15,000 for TGen ovarian cancer research

The Anne Rita Monahan Foundation recently presented $15,000 for ovarian cancer research to the Translational Genomics Research Institute (TGen).

21 Apr 2010

Medical News

Ajinomoto AminoScience introduces new resource for peptides

Positive preclinical pharmacokinetic data for XMT-1001 presented at AACR 2010

Initial results of gallium-containing compound to treat serious infection presented at AACR 2010

Immunomedics' blood assay for PAM4-protein can detect pancreatic cancer and predict early relapse

Receiving cochlear implant before 18 months of age improves child's ability to hear: Study

ARIAD presents AP26113 investigational ALK inhibitor preclinical study data at AACR annual meeting

Drugmakers raised prices last year in anticipation of new health law, Eli Lilly reports financial hit

CVS Caremark survey results of specialty pharmacy patients

Immunomedics reports study results of antibody-SN-38 conjugates for targeted cancer chemotherapy

AACN joins national, state and community organizations in support of NHDD

EGFR levels may help early detection of breast cancer

Preclinical data in neuroblastoma for perifosine to be presented at AACR 2010 Meeting

Researchers demonstrate role of HSP-90 in portal hypertension

Concateno bestowed Queen's Award for Enterprise

Study investigates potential long-term effects of maternal stature on offspring mortality

A*STAR's BMRC and SIgN award grants for twelve research projects on infectious diseases and immunology

LDR completes IDE study on Mobi-C cervical artificial disc

Findings may illuminate how cancer forms and migrates

MMRC Multiple Myeloma Genomics Initiative presented at AACR 2010

Tea for Teal event raises $15,000 for TGen ovarian cancer research

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

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