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Study: Many approved cancer drugs lack proof of added benefit

Many cancer drugs approved by the European Medicines Agency (EMA) between 1995 and 2020 lack proof of added benefit, particularly those approved through expedited ("fast track") pathways, finds a study published by The BMJ today.

28 Feb 2024

Mandatory calorie labeling could save thousands from cardiovascular deaths

The current policy of mandatory calorie labelling in large food businesses in England could potentially prevent approximately 730 deaths from cardiovascular disease (CVD) between 2022 and 2041 - and, if the policy were extended to all English food businesses, could potentially prevent around 9,200 CVD deaths over the same time period, suggests first modelled estimation of the impact of the policy published in The Lancet Public Health.

28 Feb 2024

Italians show mixed adherence to Mediterranean diet, study reveals

A comprehensive study on the Mediterranean Diet adherence among Italians reveals a predominant medium adherence level, with significant influences from demographic and lifestyle factors, despite the diet's recognized health benefits.

28 Feb 2024

Sensory cues from the opposite sex affect aging in animals

Sensory cues from the opposite sex can influence how animals age, a University of Otago-led study has found.

28 Feb 2024

Pregnancy history could unlock early interventions for women's heart health

Study reveals a strong link between a woman's obstetric history by age 40 and her risk of dying from heart disease, emphasizing the importance of pregnancy complications in predicting future cardiovascular health.

28 Feb 2024

Social factors may be linked to access to stroke treatment

For people with stroke, social factors such as education, neighborhood and employment, may be linked to whether they receive treatment with clot-busting drugs according to a preliminary study released today, February 28, 2024, that will be presented at the American Academy of Neurology's 76th Annual Meeting taking place April 13–18, 2024, in person in Denver and online.

28 Feb 2024

Seizure assistance dogs offer hope for people with drug-resistant epilepsy

For people with drug-resistant epilepsy, having a dog companion trained in detecting seizures and other epilepsy-related tasks may reduce the amount of seizures they have, according to new research published in the February 28, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 Feb 2024

Study demonstrates the deleterious effects of chronic cocaine use on functional brain networks

A collaborative research endeavor by scientists in the Departments of Radiology, Neurology, and Psychology and Neuroscience at the UNC School of Medicine have demonstrated the deleterious effects of chronic cocaine use on the functional networks in the brain.

28 Feb 2024

GTF2I gene's role in Williams syndrome and autism unraveled

Individuals with the neurodevelopmental disorder Williams syndrome have a gregarious "cocktail party" personality, while those with the opposite genetic alteration, in contrast, tend to have autistic traits and are prone to struggle socially.

28 Feb 2024

Study reveals a safe path to overcoming food allergies for older children

New research from the University of British Columbia reveals a safe path to overcoming food allergies for older children and others who can't risk consuming allergens orally to build up their resistance.

28 Feb 2024

Healthy eating reduces preeclampsia risk in pregnant women, study finds

Study suggests diets high in solid fats, refined grains, and cheese increase preeclampsia risk, whereas diets rich in vegetables, oils, and fruits may prevent it, especially among low-income Hispanic/Latin women.

28 Feb 2024

Study reveals high prevalence of BRCA1 and BRCA2 mutations in ovarian cancer patients from the Salento peninsula

A new research paper was published in Oncotarget's Volume 15 on February 22, 2024, entitled, "Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health."

28 Feb 2024

EPFL scientists uncover protein degradation mechanism preventing autoimmune reactions

Scientists at EPFL uncover the mechanism by which cells mark the protein cGAS for degradation, which is critical in preventing the immune system from mistakenly attacking the body's own tissues.

28 Feb 2024

Machine learning unveils key molecular players and immune signatures in stress cardiomyopathy

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Stress cardiomyopathy (SCM) is a reversible, self-limiting condition that manifests as left ventricular insufficiency.

28 Feb 2024

AI-based technology unlocks secrets of myasthenic-congenital syndromes

An international team of scientists led by ICREA researcher and Director of the Life Sciences Department at the Barcelona Supercomputing Centre - Centro Nacional de Supercomputación (BSC-CNS), Alfonso Valencia, has developed a technology based on artificial intelligence (AI) for the study of minority diseases and has successfully applied it to identify the possible causes of the appearance of what are known as myasthenic-congenital syndromes, a group of rare inherited disorders that limit the ability to move and cause varying degrees of muscle weakness in patients.

28 Feb 2024

UB research may offer a more streamlined approach to developing cancer drugs

Drug discovery can be a frustrating process of trial and error.

28 Feb 2024

High hospital readmission rates found among older Americans after major surgery

A new Yale study finds an increased risk of hospital readmission for older Americans within 180 days of undergoing major surgery - a risk that is particularly acute for individuals who are frail or have dementia.

28 Feb 2024

Developing a prognostic model for bladder urothelial cancer using oxidative stress signatures

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 3, entitled, "Prognostic model development and molecular subtypes identification in bladder urothelial cancer by oxidative stress signatures."

28 Feb 2024

Unlocking coronavirus structure through M protein research

For centuries, coronaviruses have triggered health crises and economic challenges, with SARS-CoV-2, the coronavirus that spreads COVID-19, being a recent example.

28 Feb 2024

Breakthrough blood test developed for early detection of sarcoidosis

A research project led by Lobelia Samavati, M.D., professor of internal medicine and molecular medicine and genetics at the Wayne State University School of Medicine, and supported by the National Institutes of Health (NIH), has developed a tool to rapidly and inexpensively diagnose sarcoidosis, a chronic inflammatory disease marked by the growth of tiny lumps called granulomas in the lungs and other organs.

28 Feb 2024