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Olfactory dysfunction may serve as an early diagnostic tool for Alzheimer's disease

A study published in the January 13, 2010 issue of the Journal of Neuroscience links a loss of smell function in Alzheimer's disease (AD) model animals with amyloid β (protein) accumulation in the brain, a distinguishing hallmark of Alzheimer's disease. Research conducted by NYU Langone Medical Center suggests that olfactory dysfunction, a common symptom of AD, may serve as an early diagnostic tool for the disease.

13 Jan 2010

Emisphere Technologies: Novo Nordisk initiates first Phase I clinical trial of GLP-1

Emisphere Technologies, Inc. today announced that Novo Nordisk has initiated its first Phase I clinical trial with a long-acting oral GLP-1 analogue (NN9924). This milestone releases a $2 million payment to Emisphere, whose proprietary Eligen® Technology is used in the formulation of NN9924.

13 Jan 2010

Study recommends improvements for scaling up child survival programs

New child survival programs must engage evaluation teams from the start to identify the major causes of child mortality in intervention areas and to ensure that appropriate resources are available to scale up coverage and treatment, according to a retrospective evaluation led by researchers at the Johns Hopkins Bloomberg School of Public Health.

13 Jan 2010

Study: Patients with specific oncogenic rearrangements of ALK gene show greater response to new therapy

Results of a new study in non-small cell lung cancer showed that patients with specific oncogenic rearrangements of the anaplastic lymphoma kinase (ALK) gene within the short arm of chromosome 2 of their tumors had a much greater response to a new therapy - an ALK-inhibitor.

13 Jan 2010

ACP supports equality of Medicaid and Medicare rates for primary care services

The American College of Physicians (ACP) today was one of 118 organizations that joined to send a letter to House and Senate leaders supporting equality of Medicaid and Medicare rates for primary care services.

13 Jan 2010

Study finds financial ties between clinical study leaders and pharmaceutical companies

Reuters reports that a new study has found "cancer researchers who design clinical trials, analyze or interpret the data, or play other key scientific roles are four times more likely to have financial ties to industry than their counterparts who have lesser roles in these studies, such as recruiting study subjects or collecting the data."

13 Jan 2010

FBR releases new PSA, Jen's Story 2

The Foundation for Biomedical Research (FBR) announced today the release of its new PSA, "Jen's Story 2," as part of its ResearchSaves national campaign. The 60-second spot reunites viewers with Jen, a real biomedical researcher who specializes in breast cancer research and is battling the disease herself.

13 Jan 2010

ATR analyses impact of Coakley's support for the Senate healthcare bill

Americans for Tax Reform today released an analysis showing the impact on Massachusetts of Marsha Coakley's support for the Senate healthcare bill. Coakley is on record supporting the Senate government healthcare bill, which contains eighteen separate tax increases. One of these is a new $2 billion per year (rising to $3 billion in 2017) tax on medical device manufacturers.

13 Jan 2010

Theragenics signs agreement with Core Oncology for distribution of TheraSeed palladium-103 brachytherapy seeds

Theragenics Corporation, a medical device company serving the surgical products and prostate cancer treatment markets, today announced that it has signed an agreement with Core Oncology, Inc. for the distribution of TheraSeed® palladium-103 brachytherapy seeds.

13 Jan 2010

Extended treatment with active ingredient increases bone volume and calcium content

Genta Incorporated today announced publication of two scientific studies that test the active ingredient in Genta’s program to develop orally available gallium-containing compounds and the Company’s marketed product, Ganite® (gallium nitrate for injection).

13 Jan 2010

Pisgah Labs files its eighth patent application for technology to prevent prescription drug abuse

According to the Office of National Drug Control Policy, prescription drug abuse is more prevalent than abuse of cocaine, heroin and methamphetamine. In fact, in the past year, prescription drug abuse ranked second only to marijuana use. In the face of this growing problem, Pisgah Labs, Inc. has just filed its eighth patent application on a technology that promises to curb prescription drug abuse.

13 Jan 2010

Retreating with gefitinib may benefit non-small cell lung cancer patients

Patients with non-small cell lung cancer in whom treatment with gefitinib is ineffective often have limited options, but results of a new study suggest that retreating patients with the same drug could have a beneficial effect.

13 Jan 2010

Send Word Now to provide emergency voice and text communication services to Unity Health System's hospitals

Send Word Now, the leading provider of emergency notification and on-demand alerting and response services, announced today that Unity Health System, a 681-bed health-care network based out of Rochester, New York, has selected Send Word Now to provide emergency voice and text communication services to its hospitals.

13 Jan 2010

University of Leicester study provides new insights into preventer and reliever treatments for asthma

A new study at the University of Leicester is probing why asthma relief inhalers might actually make asthma worse- and what can be done about it.

13 Jan 2010

Three tumor microRNAs may help identify chemoresistance in small cell lung cancer patients

At least three tumor microRNAs appear to predict when first-line chemotherapy will prove ineffective in some patients with small cell lung cancer, according to data presented at the AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer, held Jan. 11-14, 2010.

13 Jan 2010

Synta Pharmaceuticals presents preclinical results of STA-9090 at AACR-IASLC Joint Conference

Synta Pharmaceuticals Corp. (NASDAQ: SNTA), a biopharmaceutical company focused on discovering, developing, and commercializing small molecule drugs to treat severe medical conditions, today announced that preclinical results presented at the AACR-IASLC (American Academy of Cancer Research – International Association for the Study of Lung Cancer) Joint Conference based on work done at Synta and at the Dana-Farber Cancer Institute in Boston showed that STA-9090, a potent, synthetic inhibitor of heat shock protein 90 (Hsp90), demonstrated potent activity against 100% of all non-small cell lung cancer cell lines tested, including those with EGFR, HER2 or KRAS mutations including the EGFR T790 mutation that is present in roughly 50% of cases of erlotinib or gefitinib resistance.

13 Jan 2010

NexMed's NexACT technology enhances Taxol's bioavailability through oral administration

NexMed, Inc., a specialty CRO and a developer of products based on the NexACT® technology, today announced that pre-clinical results from its research and development group at Bio-Quant successfully demonstrated the ability of the NexACT technology to deliver an oral formulation of Taxol® (paclitaxel) and to enhance the drug’s bioavailability by approximately ten-fold through this oral administration. Taxol, a first line chemotherapy drug used to treat breast, lung and ovarian cancers, is currently administered through an intravenous infusion that can take up to 24 hours to complete.

13 Jan 2010

Progress on MDG targets is 'key priority' in 2010 for U.N. Secretary-General

U.N. Secretary-General Ban Ki-moon on Monday called 2010 "the year of development" and said "he would make the drive to achieve" the Millennium Development Goals (MDGs) by 2015 "one of his key priorities this year," Agence France-Presse/My Sinchew reports.

13 Jan 2010

PRP injections are ineffective for treating Achilles tendon disorder

An apparently increasingly used treatment method for a type of Achilles tendon disorder that includes injection of platelet-rich plasma into the tendon does not appear to result in greater improvement in pain or activity compared to placebo, according to results of a preliminary study published in the January 13 issue of JAMA.

13 Jan 2010

RWJF awards multi-year grants to 41 communities to reverse childhood obesity epidemic by 2015

The Robert Wood Johnson Foundation (RWJF) has awarded multi-year grants to 41 communities across the country as part of a landmark national program to reverse the childhood obesity epidemic by 2015.

13 Jan 2010

Medical News

Olfactory dysfunction may serve as an early diagnostic tool for Alzheimer's disease

Emisphere Technologies: Novo Nordisk initiates first Phase I clinical trial of GLP-1

Study recommends improvements for scaling up child survival programs

Study: Patients with specific oncogenic rearrangements of ALK gene show greater response to new therapy

ACP supports equality of Medicaid and Medicare rates for primary care services

Study finds financial ties between clinical study leaders and pharmaceutical companies

FBR releases new PSA, Jen's Story 2

ATR analyses impact of Coakley's support for the Senate healthcare bill

Theragenics signs agreement with Core Oncology for distribution of TheraSeed palladium-103 brachytherapy seeds

Extended treatment with active ingredient increases bone volume and calcium content

Pisgah Labs files its eighth patent application for technology to prevent prescription drug abuse

Retreating with gefitinib may benefit non-small cell lung cancer patients

Send Word Now to provide emergency voice and text communication services to Unity Health System's hospitals

University of Leicester study provides new insights into preventer and reliever treatments for asthma

Three tumor microRNAs may help identify chemoresistance in small cell lung cancer patients

Synta Pharmaceuticals presents preclinical results of STA-9090 at AACR-IASLC Joint Conference

NexMed's NexACT technology enhances Taxol's bioavailability through oral administration

Progress on MDG targets is 'key priority' in 2010 for U.N. Secretary-General

PRP injections are ineffective for treating Achilles tendon disorder

RWJF awards multi-year grants to 41 communities to reverse childhood obesity epidemic by 2015

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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