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Calcium-induced release identified as key driver of dangerous muscle disorders

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release.

25 Sep 2025

Study shows how early-life epigenetic 'memory' can influence adult brain inflammation

Why do some people remain healthy through childhood yet become more vulnerable to brain disorders such as dementia later in life? A KAIST (President Kwang Hyung Lee) -led team has uncovered a key part of the answer: a developmental 'switch' in astrocytes—the brain's most abundant support cells that shapes how strongly the brain's immune system reacts in adulthood.

25 Sep 2025

Circadian clock found to regulate bone breakdown

How our bodies break down and remove old and damaged bone tissue is linked to our inner circadian clock, according to a new study from the University of Surrey and the University of Sheffield.

25 Sep 2025

Antidepressant fluoxetine alters brain energy use and boosts neural plasticity

A new study shows that the widely used antidepressant fluoxetine does more than boost serotonin levels: it changes how brain cells manage their energy and rebuild their connections, potentially helping the brain "loosen up" and adapt during depression treatment.

25 Sep 2025

Mapping 100 years of bacterial evolution reveals key spreaders of antibiotic resistance

The genetic culprits responsible for the spread of multidrug resistance (MDR) in bacteria have been identified by new research mapping 100 years of bacterial evolution.

25 Sep 2025

Analysis shows potential impact of deep NIH budget cuts on future drug development

Gleevec, a cancer drug first approved for sale in 2001, has dramatically changed the lives of people with chronic myeloid leukemia.

25 Sep 2025

Lysosomal activity in worms linked to transgenerational extension of lifespan

In the Wang Lab, it's not unusual for worms to live for a long time. HHMI Janelia Research Campus Senior Group Leader Meng Wang and her team study longevity. They've shown that by overexpressing an enzyme in the lysosomes of the roundworm C. elegans, they can extend the worm's life by up to 60 percent.

25 Sep 2025

Frontline clinicians report trauma patterns in Gaza exceeding previous warzones

A British led study published by The BMJ today provides detailed data on the pattern and severity of traumatic injuries and medical conditions seen by international healthcare workers deployed to Gaza during the ongoing military invasion.

25 Sep 2025

Gladstone researchers expand mission to tackle emerging infectious threats

From influenza and COVID-19 to HIV, viruses continue to pose a serious danger to global health.

25 Sep 2025

Robotic bronchoscope reaches tiny, hard-to-access lung tumors with high accuracy

A cutting-edge bronchoscope that is guided with the help of a robot can reach very small tumors growing in hard-to-reach parts of the lung, according to results of a gold-standard randomized-controlled trial that will be presented at the European Respiratory Society (ERS) Congress in Amsterdam, the Netherlands.

25 Sep 2025

Study explains how genetics and lifestyle combined to keep a 117-year-old healthy

Scientists conducted a multiomics study of the world’s oldest verified person (117 years), uncovering protective genetic, immune, metabolic, microbiome, and epigenetic traits that supported her exceptional longevity. These findings highlight how aging and disease may, under rare circumstances, be decoupled.

25 Sep 2025

Babies living with dogs show better lung function and reduced asthma rates

Babies exposed to dog allergens in the home have a lower risk of developing asthma by the age of five years, according to research that will be presented at the European Respiratory Society (ERS) Congress in Amsterdam, the Netherlands.

25 Sep 2025

UdeM studies make a major breakthrough in predicting neurodegenerative diseases

An international research team led by Université de Montréal medical professor Shady Rahayel has made a major breakthrough in predicting neurodegenerative diseases.

25 Sep 2025

Emergency departments emerge as key entry point for hospice and palliative care

One-third of Americans will visit an emergency department, or ED, within a month of their death. While EDs are primarily purposed to provide emergent care, they're increasingly becoming an initial touchpoint for hospice and palliative care, or HPC, referrals and consultations, according to a new study from several researchers at Henry Ford Health + Michigan State University Health Sciences.

25 Sep 2025

KFF Health News' 'What the Health?': Public health further politicized under the threat of more firings

In a highly unusual White House news conference this week, President Donald Trump — without evidence — boldly blamed the painkiller Tylenol and a string of childhood vaccines for causing a recent rise in autism.

25 Sep 2025

Alcohol raises dementia risk at every level of drinking, genetic study shows

Researchers using two major cohorts and Mendelian randomization found that alcohol consumption, whether light or heavy, raises the risk of dementia. Genetic evidence shows no safe level of drinking, challenging the belief that moderate intake protects brain health.

25 Sep 2025

Organophosphate pesticide exposure linked to reduced sperm quality in healthy men

This pilot study found that urinary metabolites of organophosphate pesticides were linked to reduced sperm motility in healthy young men, though results were preliminary. Oxidative stress did not explain the association, suggesting other biological pathways may be involved.

25 Sep 2025

Do fitness apps change behavior in the long run?

A 24-month study of over 516,000 Canadians found that a commercial fitness app offering micro-incentives led to very small but sustained increases in daily step counts. Low-active users benefitted most, while very active users showed declines, highlighting the complexity of long-term app engagement.

25 Sep 2025

Mount Sinai study maps protein networks driving Alzheimer’s disease pathogenesis

A new study led by the Icahn School of Medicine at Mount Sinai offers one of the most comprehensive views yet of how brain cells interact in Alzheimer's disease, mapping protein networks that reveal communication failures and point to new therapeutic opportunities.

25 Sep 2025

COVID-19 linked to long-lasting reductions in smell even without noticeable symptoms

People who suspect that their sense of smell has been dulled after a bout of COVID-19 are likely correct, a new study using an objective, 40-odor test shows. Even those who do not notice any olfactory issues may be impaired.

25 Sep 2025

Medical News

Calcium-induced release identified as key driver of dangerous muscle disorders

Study shows how early-life epigenetic 'memory' can influence adult brain inflammation

Circadian clock found to regulate bone breakdown

Antidepressant fluoxetine alters brain energy use and boosts neural plasticity

Mapping 100 years of bacterial evolution reveals key spreaders of antibiotic resistance

Analysis shows potential impact of deep NIH budget cuts on future drug development

Lysosomal activity in worms linked to transgenerational extension of lifespan

Frontline clinicians report trauma patterns in Gaza exceeding previous warzones

Gladstone researchers expand mission to tackle emerging infectious threats

Robotic bronchoscope reaches tiny, hard-to-access lung tumors with high accuracy

Study explains how genetics and lifestyle combined to keep a 117-year-old healthy

Babies living with dogs show better lung function and reduced asthma rates

UdeM studies make a major breakthrough in predicting neurodegenerative diseases

Emergency departments emerge as key entry point for hospice and palliative care

KFF Health News' 'What the Health?': Public health further politicized under the threat of more firings

Alcohol raises dementia risk at every level of drinking, genetic study shows

Organophosphate pesticide exposure linked to reduced sperm quality in healthy men

Do fitness apps change behavior in the long run?

Mount Sinai study maps protein networks driving Alzheimer’s disease pathogenesis

COVID-19 linked to long-lasting reductions in smell even without noticeable symptoms

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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