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More insulin-producing cells from a single transcription factor switch

Researchers have found a way in mice to convert another type of pancreas cell into the critical insulin-producing beta cells that are lost in those with type I diabetes. The secret ingredient is a single transcription factor, according to the report in the August 7th issue of Cell, a Cell Press journal.

7 Aug 2009

Reform could strain community health centers

While the health care reform debate rages on Capitol Hill, sitting just a mile away is the Walker-Jones Health Center in Northeast Washington, one of about 1,200 federally-qualified community health centers across the country that provide free and reduced-cost care to millions of Americans.

7 Aug 2009

Guided care reduces cost of health care for seniors with chronic conditions

The nation's sickest and most expensive patients need fewer health care resources and cost insurers less when they are closely supported by a nurse-physician primary care team that tracks their health and offers regular support, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health.

7 Aug 2009

Cooperation between faith-based organizations and UNFPA critical to maternal health, say groups

Partnerships between faith-based organizations and UNFPA, the United Nations Population Fund, are critical to enhancing efforts to reduce maternal deaths and end violence against women.

7 Aug 2009

Community insurance co-ops, medical homes offer models for reform

Communities with nonprofit health insurance co-ops or a system of patients having "medical homes' could be useful models in a national health care overhaul.

7 Aug 2009

LDTD Technology at BASi increases speed of sample analysis

BASi provides clients with increased sample analysis speed and quick turnaround with the LDTD technology. Fast screening is combined with accurate quantification results, to benefit any bioanalytical studies.

7 Aug 2009

Netmotion Wireless boosts mobile productivity for Bell Ambulance

NetMotion Wireless has announced that it has been selected by Bell Ambulance to enable seamless roaming and data connectivity for its mobile emergency medical technicians (EMTs) and paramedics.

7 Aug 2009

Economic downturn will worsen obesity epidemic

Levels of debt have been associated with an increased risk of being fat. Researchers writing in the open access journal BMC Public Health blame the trend on the high price of healthy food, and a tendency for people worried by debt to comfort eat.

7 Aug 2009

Changes in mtDNA can cause premature ageing

The normal ageing process has long been linked to problems with cell respiration, the process through which the cells extract energy from nutrients. Researchers at the Swedish medical university Karolinska Institutet have now shown how certain proteins that are synthesised in the cellular mitochondria - popularly known as the cells' power plants - become unstable and disintegrate, which in turn can impair cell respiration and cause premature ageing.

7 Aug 2009

TB alliance appoints Marshall Burke as the organization's Head of External Affairs

The Global Alliance for TB Drug Development (TB Alliance), a not-for-profit product development partnership accelerating the discovery and development of new drugs to fight tuberculosis (TB), today announced the appointment of Marshall Burke, Ph.D. as the organization's Head of External Affairs.

7 Aug 2009

Scientists find key to strengthening immune response to chronic infection

A team of researchers from The Wistar Institute has identified a protein that could serve as a target for reprogramming immune system cells exhausted by exposure to chronic viral infection into more effective "soldiers" against certain viruses like HIV, hepatitis C, and hepatitis B, as well as some cancers, such as melanoma.

6 Aug 2009

Proteomics helps find key to keeping cells in shape

Yale University researchers have discovered how a protein within most cell membranes helps maintain normal cell size, a breakthrough in basic biology that has implications for a variety of diseases such as sickle cell anemia and disorders of the nervous system.

6 Aug 2009

Pending health care reform should not distract from making medical technology investments

In spite of the tremendous attention being paid this summer to health care reform, it is critical that investments in medical technology startups not go into a “holding pattern,” but continue unabated. So says ONSET Ventures partner Rob Kuhling.

6 Aug 2009

Senators Harkin, Kennedy and Specter honored as champions of health research

The Foundation for the National Institutes of Health, Research!America and the Albert and Mary Lasker Foundation recognized these three senators for their continued support of research for health, their leadership and shared commitment to making it a high national priority, on Tuesday evening August 4th at the Russell Senate Office Building.

6 Aug 2009

Soliris (Eculizumab) granted orphan drug designation in Europe and U.S. for atypical hemolytic uremic syndrome

Alexion Pharmaceuticals, Inc. has announced today that Soliris® (eculizumab), its first-in-class complement inhibitor, has been granted Orphan Medicinal Product Designation by the European Commission for the treatment of patients with atypical Hemolytic Uremic Syndrome (aHUS). AHUS is an ultra-rare, inherited, and life-threatening complement-inhibitor deficiency disease that often progresses to end-stage kidney disease or failure. The U.S. Food and Drug Administration granted orphan drug designation to Soliris for the same indication in May 2009. Soliris is not approved for the treatment of patients with aHUS.

6 Aug 2009

States expand kids' coverage despite widespread health care budget cuts

lthough states are facing their worst fiscal crisis since the Great Depression, 14 found the dollars this year to increase health coverage for about 250,000 children," Stateline/Finance and Commerce reports.

6 Aug 2009

Complex, eight-hour open procedure removes life-threatening blood clots from 17-year-old's lungs

After visiting the emergency room with fainting spells and shortness of breath, a 17-year-old Morningside Heights boy was diagnosed with rare, life-threatening blood clots blocking his pulmonary arteries. To address the problem, surgeons at NewYork-Presbyterian Hospital Morgan Stanley Children's Hospital successfully performed a pulmonary thromboendartectomy (PTE) surgery -- reportedly, the first time it has been performed on a child in the New York City area.

6 Aug 2009

Botanicals do not have an effect on hot flashes or on cognitive function in menopausal women

Two studies conducted by researchers at the University of Illinois at Chicago and Northwestern University have found that commonly used botanicals do not have an effect on hot flashes or on cognitive function in menopausal women.

6 Aug 2009

Discovery of possible mechanisms to protect against genetic alterations, diseases

Peering into the DNA of tiny yeast, researchers at the Moores Cancer Center at the University of California, San Diego and the San Diego Branch of the Ludwig Institute for Cancer Research have pinpointed a large number of genes that can prevent a type of genetic rearrangement that may lead to cancer and other diseases.

6 Aug 2009

Stroke doubles patients' risk of breaking a hip or femur

Stroke survivors have about twice the risk of breaking a hip or femur compared to those without stroke - and the risk is even greater for younger patients, women and those with recent strokes, Dutch researchers report in Stroke: Journal of the American Heart Association.

6 Aug 2009