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Handle with care: Telomeres resemble DNA fragile sites

Telomeres, the repetitive sequences of DNA at the ends of linear chromosomes, have an important function: They protect vulnerable chromosome ends from molecular attack.

9 Jul 2009

Embryonic stem cells used to create human sperm

Human sperm have been created using embryonic stem cells for the first time in a scientific development which will lead researchers to a better understanding of the causes of infertility.

9 Jul 2009

Dental problems may predict future medical issues

Dental disease may be a wake-up call that your diet is harming your body. "The five-alarm fire bell of a tooth ache is difficult to ignore," says Dr. Philippe P. Hujoel, professor of dental public health sciences at the University of Washington (UW) School of Dentistry in Seattle. Beyond the immediate distress, dental pain may portend future medical problems. It may be a warning that the high-glycemic diet that led to dental problems in the short term may, in the long term, lead to potentially serious chronic diseases.

9 Jul 2009

Newborn brain cells improve our ability to navigate our environment

Although the fact that we generate new brain cells throughout life is no longer disputed, their purpose has been the topic of much debate. Now, an international collaboration of researchers made a big leap forward in understanding what all these newborn neurons might actually do. Their study, published in the July 10, 2009, issue of the journal Science, illustrates how these young cells improve our ability to navigate our environment.

9 Jul 2009

Xerostomia linked to use of multiple medications

Approximately ninety-one percent of dentists say patients complaining about dry mouth are taking multiple medications, according to a nationwide member survey conducted by the Academy of General Dentistry (AGD).

9 Jul 2009

Ethicists urge inclusion of pregnant women in Federal child-health study

A team of ethicists from Johns Hopkins, Duke and Georgetown universities is urging organizers of a recently begun $3 billion decades-long study of children's health to immediately add provisions to look at the health and medical profiles of the children's mothers during their pregnancies.

9 Jul 2009

One secret to how tuberculosis resists the host immune system

Mycobacterium tuberculosis is arguably the world's most successful infectious agent because it knows how to avoid elimination by slowing its own growth to a crawl. Now, a report in the July 10 issue of the journal Cell, a Cell Press publication, offers new insight into the bugs' talent for meager living.

9 Jul 2009

Innovative study brings us closer to an explanation for Crohn's disease

Twenty-five per cent of Crohn's disease patients have a mutation in what is called the NOD2 gene, but it is not precisely known how this mutation influences the disease.

9 Jul 2009

Optimum "sperm load"

Attractive males release fewer sperm per mating to maximise their chances of producing offspring across a range of females, according to a new paper on the evolution of ejaculation strategies. The findings by researchers at UCL (University College London) and the University of Oxford suggest that, paradoxically, matings with attractive males may be less fertile than those with unattractive ones.

9 Jul 2009

Two reproductive factors are important predictors of death from ovarian cancer

Researchers from the Centers for Disease Control and Prevention (CDC) found that survival among women with ovarian cancer is influenced by age of menarche and total number of lifetime ovulatory cycles.

9 Jul 2009

Environmental manganese and cancer mortality rates

In the first ecological study of its kind in the world, a Wake Forest University Baptist Medical Center researcher has uncovered the unique finding that groundwater and airborne manganese in North Carolina correlates with cancer mortality at the county level.

9 Jul 2009

New heart disease risk score outperforms existing test

An independent external validation of QRISK® - a new score for predicting a person's risk of heart disease - has shown that it performs better than the existing test and should be recommended for use in the United Kingdom by the National Institute for Health and Clinical Excellence (NICE).

9 Jul 2009

Discovery of key gene for bone development that when mutated lead to dwarfism

Scientists have just discovered the gene behind Recessive Omodysplasia, a rare skeletal disease characterised by short-limbed dwarfism and craniofacial anomalies.

9 Jul 2009

Study may lead to new drugs to treat cough

Scientists investigating the cough reflex have discovered a new group of molecules on the surface of nerve cells that make us cough when irritated.

9 Jul 2009

Relationship between migraine history and breast cancer risk among premenopausal and postmenopausal women

The relationship between migraine headaches in women and a significant reduction in breast cancer risk has been confirmed in a follow-on study to landmark research published last year and conducted by scientists at Fred Hutchinson Cancer Research Center. The new study found a 26 percent reduced risk of breast cancer among both premenopausal and postmenopausal women with a clinical diagnosis of migraines.

9 Jul 2009

Research may hold key to maintaining embryonic stem cells in lab

In a new study that could transform embryonic stem cell (ES cell) research, scientists at UT Southwestern Medical Center have discovered why mouse ES cells can be easily grown in a laboratory while other mammalian ES cells are difficult, if not impossible, to maintain.

9 Jul 2009

Biden formally announces $155 billion agreement with hospitals

Politico is reporting on its Political Intelligence Blog that Vice President Joe Biden, subbing for President Obama who is at the G-8 economic summit in Italy, formally announced the latest deal with the industry. "The nation's hospitals have tentatively agreed to forego about $155 billion in government payments for Medicaid and Medicare over the next decade -- about 20 percent of the $1 trillion projected to be needed to extend health coverage to about 47 million uninsured Americans."

8 Jul 2009

Hospitals, after agreeing to cuts, push ahead with a full agenda

With the Obama administration's help, hospitals are moving aggressively to resolve their biggest objections to legislative proposals to overhaul the health system.

8 Jul 2009

Emanuel reassures Democrats on public insurance option

"White House Chief of Staff Rahm Emanuel reassured House Democrats on Tuesday night that President Barack Obama strongly backs a government-run health insurance plan, seeking to quell a firestorm among liberals upset at Emanuel's comments in the Wall Street Journal that suggested such a plan could be delayed," Roll Call reports.

8 Jul 2009

Health reform legislation will impact preventive and wellness programs

Reuters reports: "Efforts to overhaul the U.S. healthcare system and expand coverage to millions of uninsured could lead some wellness programs to expand and others to constrict, experts say.... In all of the bills in Congress, insurers would be required to cover some preventive services, and all of the bills include prevention and wellness incentives.

8 Jul 2009