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Breakthrough in sickle cell disease and thalassemia research

Researchers have identified a gene that directly affects the production of a form of hemoglobin that is instrumental in modifying the severity of the inherited blood disorders sickle cell disease and thalassemia.

5 Dec 2008

Discovery of novel prion infectivity in white and brown fat tissues of mice

Prion diseases, also known as transmissible spongiform encephalopathies, are infectious progressive fatal neurodegenerative diseases which affect humans as well as wild and domestic animals.

5 Dec 2008

New recommendations on late-onset hypogonadism

The January issue of European Urology, the official journal of the European Association of Urology published by Elsevier, will feature new recommendations on late-onset hypogonadism (LOH), recently formulated by major scientific organizations.

5 Dec 2008

New method of producing synthetic bone

A method of producing synthetic bone, using techniques normally used to make catalytic converters for cars, is being developed by researchers at WMG at the University of Warwick.

5 Dec 2008

Model unravels rules that govern how genes are switched on and off

For years, scientists have struggled to decipher the genetic instruction book that details where and when the 20,000 genes in a human cell will be turned on or off.

5 Dec 2008

Taiji, qigon and support groups help those with dementia

Those diagnosed with early stage dementia can slow their physical, mental and psychological decline by taking part in therapeutic programs that combine counseling, support groups, Taiji and qigong, researchers report.

5 Dec 2008

Metabolic reactions: Less is more in single-celled organisms

A Northwestern University study has found a surprising similarity among four quite different organisms.

5 Dec 2008

Concerns about embryo disposition - 500,000 frozen embryos currently in storage

Fertility patients who are done having children feel responsible for the stored, frozen embryos left over from their treatment, yet more than half are against implanting the embryos in anyone else, according to a new study by researchers at Duke University Medical Center.

5 Dec 2008

Intervention in infants with cystic fibrosis key to slowing progression

Early detection of lung disease in cystic fibrosis (CF), combined with aggressive treatment in infants, may be the key to controlling the progression of the disease, according to a recent study.

5 Dec 2008

Interferon as long-term treatment for hepatitis C not effective

Use of the drug interferon as a long-term maintenance strategy to slow the progression of liver disease associated with the hepatitis C virus is ineffective, UT Southwestern Medical Center researchers and their colleagues from nine other institutions have found in a multicenter study.

5 Dec 2008

Happiness really does rub off

Happiness really does rub off-a person's happiness depends on the happiness of others with whom they are connected, finds research published on bmj.com.

5 Dec 2008

Genetic ancestry of African-Americans reveals new insights about gene expression

The amount of proteins produced in cells—a fundamental determinant of biological outcomes collectively known as gene expression—varies in African American individuals depending on their proportion of African or European genetic ancestry.

5 Dec 2008

Chromatin packaging helps decipher how cancer develops

To decipher how cancer develops, Johns Hopkins Kimmel Cancer Center investigators say researchers must take a closer look at the packaging.

5 Dec 2008

Researchers focus on phosphoinositide 3-kinase pathway in cancer research

Researchers are taking a closer look at the phosphoinositide 3-kinase (PI3-kinase) pathway as studies continue to demonstrate that inhibiting this biological route suppresses tumor growth, reports Genetic Engineering & Biotechnology News (GEN ).

5 Dec 2008

Extraordinary immune cells may hold the key to managing HIV

People who manage to control HIV on their own are providing scientists with valuable information about how the immune system eliminates virus-infected cells.

5 Dec 2008

Analysis of intensive care units shows drug and alcohol abuse double risk of admission

While the personal health and safety risks of drug and alcohol abuse are well-documented, a new study by researchers at LDS Hospital and Brigham Young University suggests substance dependence increases medical costs by way of the intensive care unit.

5 Dec 2008

Idiopathic pulmonary fibrosis linked to heart attacks

Patients with idiopathic pulmonary fibrosis (IPF) are three times as likely to experience severe coronary events - including heart attacks - than people without the disease, according to a recent study that analyzed the risk of cardiovascular disease in nearly 1,000 patients with IPF and more than 3,500 matched controls.

5 Dec 2008

Dormant stem cells for emergencies

Many specialized cells, such as in the skin, intestinal mucosa or blood, have a lifespan of only a few days.

5 Dec 2008

Discovery of MEDNIK syndrome

Canadian researchers announce the discovery of MEDNIK Syndrome, a debilitating genetic syndrome.

5 Dec 2008

Stem cells derived from bone marrow may offer novel therapeutic option for epidermolysis bullosa

Stem cells derived from bone marrow may serve as a novel therapeutic option to treat a disease called epidermolysis bullosa (EB), a disorder characterized by extraordinarily fragile skin, according to a study prepublished online in Blood, the official journal of the American Society of Hematology.

5 Dec 2008