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Early-acting autophagy genes extend lifespan through alternative "garbage disposal" pathway in neurons

Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. In the January 4th issue of Nature Aging, it was noted that scientists from the Buck Institute, Sanford Burnham Prebys and Rutgers University have uncovered possible novel functions for various autophagy genes, which may control different forms of disposal including misfolded proteins - and ultimately affect aging.

4 Jan 2024

AI could revolutionize ambulance care by providing real-time patient assessment

Assessing how seriously injured a person is, involves weighing up lots of different parameters fast. If healthcare professionals could get support making fast-paced, life-critical decisions from an AI tool, more lives could be saved.

4 Jan 2024

Unmasking the persistent threats of long-COVID's pulmonary sequelae

A collaborative study led by Dr. Estefanía Nova-Lamperti of the Universidad de Concepción, Dr. Gonzalo Labarca of Harvard University, and Mauricio Hernández, of MELISA Institute, and which included the participation of researchers from leading academic institutions, sought to identify the sequelae associated with long-term pulmonary dysfunction (L-PDD) in patients with COVID-19.

4 Jan 2024

CLivD score shows promise in early detection of steatotic liver disease and advanced fibrosis

Chronic liver disease, a growing threat to global health, often progresses silently in its early stages.

4 Jan 2024

Study identifies mitochondrial dysfunction as cause of long-COVID fatigue

Researchers from Amsterdam UMC and Vrije Universiteit Amsterdam (VU) have discovered that the persistent fatigue in patients with long-COVID has a biological cause, namely mitochondria in muscle cells that produce less energy than in healthy patients.

4 Jan 2024

Researchers develop peptide to target "chaotic" MYC protein in 75% of cancers

Meet MYC, the shapeless protein responsible for making the majority of human cancer cases worse.

4 Jan 2024

Salk scientists map brain circuit triggering the crippling panic attacks

Overwhelming fear, sweaty palms, shortness of breath, rapid heart rate - these are the symptoms of a panic attack, which people with panic disorder have frequently and unexpectedly.

4 Jan 2024

Stanford Medicine researchers demonstrate new way to temporarily heighten hypnotizablity

How deeply someone can be hypnotized - known as hypnotizability - appears to be a stable trait that changes little throughout adulthood, much like personality and IQ.

4 Jan 2024

Gut microbiome plays a role in immune response to mRNA COVID vaccines

Researchers from Karolinska Institutet in Sweden have discovered that the gut microbiome can influence how well people respond to mRNA COVID vaccines.

4 Jan 2024

PharmaKure granted MHRA Clinical Trial Authorisation (CTA) for PK051 for the treatment of mild cognitive impairment due to Alzheimer’s Disease

Clinical Trial Authorisation application granted for combined drug PK051 targeting amyloid deposits associated with Alzheimer’s Disease.

From PharmaKure 4 Jan 2024

IDO2 deficiency in mice leads to behavioral abnormalities resembling autism spectrum disorder

Over the past decades, scientists have made substantial progress unveiling the underlying mechanisms behind many psychiatric disorders.

4 Jan 2024

Sugar showdown: Which sweetener impacts insulin sensitivity the most?

The effects of four types of sweeteners on insulin sensitivity in young adults.

4 Jan 2024

Could your diet impact endometriosis? Research points to dietary insights for treatment

The role of dietary ingredients in modifying the progression and development of endometriosis.

4 Jan 2024

Global study reveals varied intention to receive monkeypox vaccine: 61% prevalence worldwide

The global prevalence and regional differences in the intention to receive the monkeypox.

4 Jan 2024

Woman petitions health insurer after company approves — then rejects — her infusions

When KFF Health News published an article in August about the "prior authorization hell" Sally Nix said she went through to secure approval from her insurance company for the expensive monthly infusions she needs, we thought her story had a happy ending.

4 Jan 2024

Doctors are as vulnerable to addiction as anyone. California grapples with a response.

Ariella Morrow, an internal medicine doctor, gradually slid from healthy self-esteem and professional success into the depths of depression.

4 Jan 2024

Study finds previously unidentified genetic mutation in a small protein provides significant protection against Parkinson’s disease

Researchers explored the effects of a small humanin-like peptide 2 (SHLP2) variant on mitochondrial function.

4 Jan 2024

Chronic ear infections linked to lasting brain and language deficits in children

Ear infections are a common childhood experience, but a new study suggests parents should take these infections seriously to preserve their children's language development.

4 Jan 2024

Diet-related inflammation may raise stroke risk, US study finds

The relationship between the dietary inflammatory index (DII) and stroke incidence.

4 Jan 2024

New compound effective against bacterial species resistant to multiple classes of existing antibiotics

Recent studies by Zampaloni et al. and Pahil et al. published in the journal Nature describe a novel method of inhibiting the growth of Gram-negative bacteria such as Acinetobacter using antibiotics consisting of macrocyclic peptides that target the bacterial protein bridge machinery that transports lipopolysaccharides from the cytoplasm to the outer membrane.

4 Jan 2024

Medical News

Early-acting autophagy genes extend lifespan through alternative "garbage disposal" pathway in neurons

AI could revolutionize ambulance care by providing real-time patient assessment

Unmasking the persistent threats of long-COVID's pulmonary sequelae

CLivD score shows promise in early detection of steatotic liver disease and advanced fibrosis

Study identifies mitochondrial dysfunction as cause of long-COVID fatigue

Researchers develop peptide to target "chaotic" MYC protein in 75% of cancers

Salk scientists map brain circuit triggering the crippling panic attacks

Stanford Medicine researchers demonstrate new way to temporarily heighten hypnotizablity

Gut microbiome plays a role in immune response to mRNA COVID vaccines

PharmaKure granted MHRA Clinical Trial Authorisation (CTA) for PK051 for the treatment of mild cognitive impairment due to Alzheimer’s Disease

IDO2 deficiency in mice leads to behavioral abnormalities resembling autism spectrum disorder

Sugar showdown: Which sweetener impacts insulin sensitivity the most?

Could your diet impact endometriosis? Research points to dietary insights for treatment

Global study reveals varied intention to receive monkeypox vaccine: 61% prevalence worldwide

Woman petitions health insurer after company approves — then rejects — her infusions

Doctors are as vulnerable to addiction as anyone. California grapples with a response.

Study finds previously unidentified genetic mutation in a small protein provides significant protection against Parkinson’s disease

Chronic ear infections linked to lasting brain and language deficits in children

Diet-related inflammation may raise stroke risk, US study finds

New compound effective against bacterial species resistant to multiple classes of existing antibiotics

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

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