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Artificial intelligence used to diagnose metastatic cancer

When doctors are managing care for women with breast cancer, the information available to them profoundly influences the type of care they recommend. Knowing whether a woman's cancer has metastasized, for instance, directly affects how her doctors will approach treatment -- which may in turn influence the outcome of that treatment.

28 Jul 2009

Smoking increases likelihood that pancreatic ductal adenocarcinoma will become metastatic

Smoking has once again been implicated in the development of advanced cancer. Exposure to nicotine by way of cigarette smoking may increase the likelihood that pancreatic ductal adenocarcinoma will become metastatic, according to researchers from the Kimmel Cancer Center at Jefferson.

27 Jul 2009

Cost effectiveness study looks at potential value of new genetic test for guiding chemotherapy treatment

For the 29,000 patients in the United States with metastatic colorectal cancer, chemotherapy with irinotecan is a standard treatment that has been shown to improve survival. But for more than one in 10 of these patients, a variation in their DNA means that this treatment could result in a severe reduction in their white blood cell count, leading to a high risk of bacterial infection and possible subsequent death.

27 Jul 2009

Research adds to growing understanding of the metabolic consequences of assisted reproductive techniques

Research to be presented at the Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB), the foremost society for research into all aspects of eating and drinking behavior, finds that assisted reproductive techniques alter the expression of genes that are important for metabolism and the transport of nutrients in the placenta of mice.

27 Jul 2009

System 50 years out of date for chronic illness

Many people with chronic health conditions have more than one disease, which makes caring for them much more complex. Unfortunately, the way our health system is structured now, and the way it is paid for, reflects the health needs our society had about 50 years ago.

27 Jul 2009

Nanodiamonds hold promise for wound-healing applications

Bacterial infection is a major health threat to patients with severe burns and other kinds of serious wounds such as traumatic bone fractures. Recent studies have identified an important new weapon for fighting infection and healing wounds: insulin.

27 Jul 2009

Trial to begin on alternative treatment for depression

The University of New South Wales (UNSW) and The Black Dog Institute are seeking participants for a trial of a new, non-invasive form of brain stimulation therapy for depression, known as Direct Current Stimulation (DCS).

27 Jul 2009

New clues about the roots of neurological disease

Switching off a key DNA repair system in the developing nervous system is linked to smaller brain size as well as problems in brain structures vital to movement, memory and emotion, according to new research led by St. Jude Children's Research Hospital scientists.

27 Jul 2009

Autophagy helps HIV to proliferate

Not satisfied with simply thwarting its host's defensive maneuvers, HIV actually twists one to its advantage, based on new findings from Kyei et al. in the July 27, 2009 issue of the Journal of Cell Biology. Vojo Deretic and colleagues suggest that autophagy - a stress response process - helps HIV to proliferate and that conversely, blocking autophagy lessens HIV production.

27 Jul 2009

New technique captures bacterial infection on film

Researchers have developed a new technique that allows them to make a movie of bacteria infecting their living host.

27 Jul 2009

Effect of sunlight exposure on cognitive function among depressed and non-depressed participants

A lack of sunlight is associated with reduced cognitive function among depressed people. Researchers writing in BioMed Central's open access journal Environmental Health used weather data from NASA satellites to measure sunlight exposure across the United States and linked this information to the prevalence of cognitive impairment in depressed people.

27 Jul 2009

Age-prioritized use of antivirals during an influenza pandemic

A model of influenza transmission and treatment suggests that, if the current swine flu pandemic behaves like the 1918 flu, antiviral treatment should be reserved for the young.

27 Jul 2009

Intensive glucose control halves complications of longstanding type 1 diabetes

Near-normal control of glucose beginning as soon as possible after diagnosis would greatly improve the long-term prognosis of type 1 diabetes, concludes a study published in the July 27, 2009, issue of the Archives of Internal Medicine, which updates information about the clinical course of type 1 diabetes.

27 Jul 2009

Obesity expert says rates of severe childhood obesity have tripled

Rates of severe childhood obesity have tripled in the last 25 years, according to a recent study by an obesity expert at Brenner Children's Hospital.

27 Jul 2009

Diets high in calcium and dairy products in childhood may lower mortality

Suggestive evidence points to the possibility that children who have a diet high in calcium and who consume dairy products may have a lower mortality rate than those who don't, according to a study by researchers in Bristol and Brisbane, published in the journal Heart.

27 Jul 2009

University at Buffalo start-up provides innovative digital sperm analysis to infertile couples worldwide

Couples struggling with fertility problems have a new option for assessing their ability to have a child with the start-up of a new Buffalo-based company called LifeCell Dx, Inc. (LCDX).

27 Jul 2009

Enzyme implicated in blood flow in Alzheimer’s, disease progression

Researchers have discovered that the enzyme, endothelin converting enzyme-2 (ECE-2), may cause the decrease in blood flow in the brain seen in Alzheimer's disease and contribute to progression of the disease.

27 Jul 2009

Adding a drug called neostigmine to epidural analgesia reduces dose needed during labor

Adding a drug called neostigmine to epidural analgesia during labor can reduce the amount of anesthetic drug required, while avoiding potential complications caused by morphine-like "opioid" drugs, according to a study in the August issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

27 Jul 2009

New system may allow use of xenon to protect newborn brain

Breathing xenon gas can help protect the infant brain from damage caused by oxygen deprivation, but the xenon's high cost and scarcity has precluded its widespread use.

27 Jul 2009

Seattle Genetics starts Brentuximab Vedotin retreatment trial

Seattle Genetics, Inc. has announced that it has initiated a phase II clinical trial of brentuximab vedotin (SGN-35), an antibody-drug conjugate (ADC), for the retreatment of patients with Hodgkin lymphoma and systemic anaplastic large cell lymphoma (ALCL).

27 Jul 2009