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Test predicts who will develop end-stage renal disease

Measuring kidney function by assessing two different factors-glomerular filtration rate (GFR) and urinary albumin levels-helps determine which patients with chronic kidney disease (CKD) will develop end-stage renal disease (ESRD), according to a study appearing in the May 2009 issue of the Journal of the American Society Nephrology (JASN).

9 Apr 2009

Stakeholders participate in regional White House forum on health care reform

At Monday's White House forum on health care reform held in Los Angeles, the discussion concerning how to fix our broken health care system and cover the 47 million Americans (6.8 million Californians) who are uninsured underscored the need for action now.

9 Apr 2009

Soybean chemicals may reduce menopause symptoms

Soy aglycons of isoflavone (SAI), a group of soybean constituent chemicals, have been shown to promote health in a rat model of the menopause.

9 Apr 2009

Serentis begins trial with first-in-class SRD441 for eczema

Serentis, a privately owned biopharmaceutical company, announced that it has commenced patient recruitment in a Phase II clinical trial for atopic dermatitis (AD), a type of eczema.

9 Apr 2009

Discovery of gene that protects against leukemia

Researchers have identified a gene that controls the rapid production and differentiation of the stem cells that produce all blood cell types -- a discovery that could eventually open the door to more streamlined treatments for leukemia and other blood cancers, in which blood cells proliferate out of control.

9 Apr 2009

Novel method for comprehensive proteome analysis

Investigators at Burnham Institute for Medical Research (Burnham) have deciphered a large percentage of the total protein complement (proteome) in Schizosaccharomyces pombe (S. pombe) fission yeast.

9 Apr 2009

Rural AIDS and HIV expert comments on media campaign

A recent study revealed that the public's concern about the HIV/AIDS problem in the United States has lessened: In 1995, 44 percent of people surveyed considered HIV/AIDS the most urgent health problem, but only 5 percent of study participants reported feeling this way today, said William L. Yarber, senior director of the Rural Center for AIDS/STD Prevention at Indiana University.

9 Apr 2009

Research could lead to new non-antibiotic drugs to counter hospital infections

Lack of an adequate amount of the mineral phosphate can turn a common bacterium into a killer, according to research to be published in the April 14, 2009, issue of the Proceedings of the National Academies of Science.

9 Apr 2009

New research should ease constipation

If you hate prune juice and chalky fiber supplements, just sit down and relax.

9 Apr 2009

Clinical trials for two compounds show promise in advanced prostate cancer

In a paper published online this week in Science Express (the online version of Science magazine), researchers report that early clinical trials for two compounds, MDV3100 and RD162, show initial promise for patients suffering from an advanced metastatic form of the disease known as castration-resistant prostate cancer.

9 Apr 2009

Dopamine agonists trigger destructive behaviors

A new study conducted at Mayo Clinic reports that one in six patients receiving therapeutic doses of certain drugs for Parkinson's disease develops new-onset, potentially destructive behaviors, notably compulsive gambling or hypersexuality.

9 Apr 2009

Kidney reconstruction performed though single incision hidden in the navel

With a single incision hidden in the navel, surgeons at the University of California, San Diego Medical Center have successfully removed a cancerous kidney tumor while saving the patient's kidney.

9 Apr 2009

Children can add problems and stress to a marriage

What married couples have suspected for years is now proven by researchers at the University of Denver (DU) and Texas A&M - children can add problems and stress to a marriage.

9 Apr 2009

Johns Hopkins tightens rules on industry interactions

Johns Hopkins Medicine has adopted a new policy that significantly limits interactions with industry while ensuring effective, principled and appropriate partnerships with drug and medical device makers.

9 Apr 2009

New common pathway in neurodegenerative disease is a possible door to a point of no return

A just-out study suggests that what keeps chronic nervous system diseases such as Alzheimer's, Huntington's and ALS going - until they overcome the internal protective mechanisms a body can throw at them - may largely come down to poor conversational skills.

9 Apr 2009

Mylan settles Clarinex patent case

Mylan Inc. has announced the settlement of all patent litigation relating to Desloratadine Tablets, 5 mg, the generic version of Schering- Plough's Clarinex allergy medication.

9 Apr 2009

Youth as young as 12 engaging in risky sexual activity

Middle school youth are engaging in sexual intercourse as early as age 12, according to a study by researchers at The University of Texas School of Public Health.

9 Apr 2009

Merck & Co and Cardiome sign agreement for Vernakalant

Merck & Co., Inc. and Cardiome Pharma Corp. has announced a collaboration and license agreement for the development and commercialization of vernakalant, an investigational candidate for the treatment of atrial fibrillation.

9 Apr 2009

Medtronic commences abdominal aortic aneurysm stent graft study

Medtronic, Inc. has announced the start of ENGAGE, the largest ever study of its kind, which will evaluate the performance of the Endurant stent graft, an implantable medical device designed to provide an advanced minimally-invasive alternative to open surgical repair of abdominal aortic aneurysms.

9 Apr 2009

Many skin cancer patients do not receive sentinel lymph node biopsy

Although clinical practice guidelines recommend sentinel lymph node (SLN) biopsy for many patients with clinically node-negative melanoma, a new analysis from the National Cancer Database (NCDB) of the American College of Surgeons (ACS) has found approximately half of patients do not receive recommended evaluation of their lymph nodes and that the type of health insurance a patient has, the type of hospital delivering treatment, and the hospital's geographic region are all associated with provider compliance with those guidelines.

9 Apr 2009