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A.P. Pharma submits NDA for APF530 in chemo-induced nausea and vomiting

A.P. Pharma, Inc. has announced that it has submitted a New Drug Application (NDA) for its lead product, APF530, to the U.S. Food and Drug Administration (FDA). APF530 is being developed for the prevention of chemotherapy-induced nausea and vomiting (CINV) and is a long-acting formulation of granisetron that utilizes the Company's proprietary Biochronomer drug delivery system.

18 May 2009

Discovery of neurons that 'mirror' the attention of others

Whether a monkey is looking to the left or merely watching another monkey looking that way, the same neurons in his brain are firing, according to researchers at the Duke University Medical Center.

18 May 2009

Obesity appears to play a protective role in heart disease

Being overweight or obese is a leading contributor to cardiovascular disease (CVD) and associated risk factors; however, in patients with established CVD, obesity appears to play a protective role.

18 May 2009

Relationship discovered between tumors and depression

In a study that could help explain the connections between depression and cancer, researchers at the University of Chicago have used an animal model to find, for the first time, a biological link between tumors and negative mood changes.

18 May 2009

Women more susceptible to damaging effects of smoking than men

Women may be more susceptible to the lung damaging effects of smoking than men, according to new research by Inga-Cecilie Soerheim, M.D., and her colleagues from Channing Laboratory, Brigham and Women's Hospital and University of Bergen, Norway.

18 May 2009

Discovery in colon cancer prevention

A new study finds that individuals who have low expression of the "Celebrex gene," 15-PGDH, are actually resistant to Celebrex treatment when used to prevent colon cancer.

18 May 2009

Discovery of molecular pathway behind invasive prostate cancers

University of Cincinnati (UC) cancer and cell biologists have identified a new molecular pathway key to the development of invasive prostate cancers.

18 May 2009

Researchers look at eczema asthma link

Many young children who get a severe skin rash develop asthma months or years later. Doctors call the progression from eczema, or atopic dermatitis, to breathing problems the atopic march. In the May 2009 issue of PLoS Biology, scientists at Washington University School of Medicine in St. Louis report another step taken towards understanding the process of atopic march.

18 May 2009

New asthma treatment bronchial thermoplasty improves patient quality of life

Chronic asthma sufferers may find new relief in a simple, minimally invasive outpatient procedure known as bronchial thermoplasty, which uses controlled radiofrequency-generated heat to treat the muscles of the airways, preventing them from constricting and narrowing.

18 May 2009

Disruption of immune-system pathway key step in cancer progression

Human immune cells communicate constantly with one another as they coordinate to fight off infection and other threats.

18 May 2009

Rapid test for prostate cancer

Researchers have developed the test by using light energy to measure the level of citrate in fluid samples from the prostate gland. The technique could provide the basis of a rapid means of detecting prostate cancer in the future. Almost a quarter of male cancers in the UK are diagnosed as prostate cancer and more than 10,000 men die from the disease each year.

18 May 2009

Trace elements unbalanced in dialysis patients

Abnormal levels of trace elements may explain dialysis morbidity. A systematic review published in the open access journal BMC Medicine has shown that, compared to healthy controls, dialysis patients have significantly different blood concentrations of trace elements.

18 May 2009

Industry groups reiterate commitment to reduce health spending growth

The six industry groups that pledged to reduce health care spending growth by $2 trillion over 10 years on Friday issued a statement reaffirming their commitment to work toward the goal, Roll Call reports (Murray, Roll Call, 5/15).

18 May 2009

Washington Post examines lobbying efforts of health information technology industry

The Washington Post on Saturday examined the role of the Healthcare Information and Management Systems Society in lobbying for the national adoption of health information technology as part of health reform efforts.

18 May 2009

California Governor outlines cuts to address State's budget deficit problems

California Gov. Arnold Schwarzenegger (R) outlined two budget proposals to address the state's budget problems, and both plans would affect health care, the Los Angeles Times reports.

18 May 2009

California mental health advocates raise concern over treatment of ICE detainees

The San Diego Tribune on Monday profiled the La Mesa, Calif.-based private psychiatric hospital Alvarado Parkway Institute. Some advocates say that the hospital is in a network of private hospitals that U.S. Immigration and Customs Enforcement uses to hold "severely" mentally ill detainees nationwide, often "out of reach of lawyers and even their families," the Tribune reports.

18 May 2009

American Indian tribes to get $500 million in stimulus funds for health projects

Newly appointed IHS Director Yvette Roubideaux on Friday announced that American Indian tribes will receive $500 million as part of the $787 billion economic stimulus package to fund health care projects, the Green Bay Press-Gazette reports.

18 May 2009

Global poverty eradication efforts should start with health issues, opinion piece says

"Eradicating global poverty starts with the health of the world's poor," Bill Frist, former U.S. Senate Majority leader and currently a member of the Millennium Challenge Corporation's (MCC) Board of Directors, writes in a Charlotte Observer opinion piece.

18 May 2009

Global AIDS coordinator Goosby should serve as 'fierce advocate' for pediatric HIV/AIDS programs, letter to editor Says

"The details of President Obama's new global health initiative have left many concerned that the financing described does not reflect the commitment required to lead the United States' efforts in the global fight against HIV and AIDS," Jennifer Delaney, executive director of Global Action for Children, writes in a New York Times letter to the editor.

18 May 2009

Sex workers in Pakistan give recommendations on HIV prevention to health officials

Although the recorded HIV prevalence in Pakistan is relatively low, health officials are concerned that a concentrated epidemic of the virus among injection drug users could carry over to commercial sex workers and other high risk groups in the country, IRIN/PlusNews reports.

18 May 2009