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Leptin influences baseline dopamine levels and motivation to eat

As we all know from experience, people eat not only because they are hungry, but also because the food just simply tastes too good to pass up. Now, a new study in the August 6th Cell Metabolism, a Cell Press publication, helps to explain how leptin, a hormone produced by fat tissue, influences that motivation to eat.

5 Aug 2009

New discovery about dystonia

Most people who carry a genetic mutation for a movement disorder called dystonia will never develop symptoms, a phenomenon that has puzzled scientists since the first genetic mutation was identified in the 1990's.

5 Aug 2009

Wolters Kluwer Health announces release of new health care software

Wolters Kluwer Health today unveiled ProVation® Care Plans, an innovative software solution that arms nurses, pharmacists, therapists and other caregivers with the actionable evidence they need to effectively enhance practice, improve patient safety and demonstrate compliance with credentialing and regulatory standards.

5 Aug 2009

Appeals court affirms invalidation of Yasmin patent

Teva Pharmaceutical Industries Ltd. (Nasdaq: TEVA) announced today that the U.S. Court of Appeals for the Federal Circuit has affirmed a ruling by the U.S. District Court for the District of New Jersey finding Bayer Schering's U.S. Patent No. 6,787,531 invalid. The patent is listed in the Orange Book for Bayer's oral contraception Yasmin®.

5 Aug 2009

Innovative diabetes drug discovery partnership

The Juvenile Diabetes Research Foundation said today that it has entered into a novel collaborative research agreement with the Genomics Institute of the Novartis Research Foundation (GNF) to create a diabetes drug discovery and development platform.

5 Aug 2009

Discovery of novel function of hormone found in gut that may lower glucose levels in diabetes

A research team led by Dr. Tony Lam at the Toronto General Research Institute and the University of Toronto discovered a novel function of a hormone found in the gut that might potentially lower glucose levels in diabetes.

5 Aug 2009

Less is more when it comes to blood transfusions

A new study suggests that blood transfusions for hospitalized cardiac patients should be a last resort because they double the risk of infection and increase by four times the risk of death.

5 Aug 2009

Research looks at cellular stress response to low oxygen

Gary Chiang, Ph.D., and colleagues at Burnham Institute for Medical Research (Burnham) have elucidated how the stability of the REDD1 protein is regulated. The REDD1 protein is a critical inhibitor of the mTOR signaling pathway, which controls cell growth and proliferation.

5 Aug 2009

Positivity speeds recovery from whiplash

Positive thoughts bring positive things to people and it's well documented these expectations have helped people recover from a number of health conditions. But until now, not much was known about the correlation between that belief and the recovery from injuries like whiplash.

5 Aug 2009

Health care reform must avoid conflicts-of-interest

As President Obama and Congress weigh changes in the nation’s health care system they must avoid creating a system where physicians are financially motivated to pressure patients into mandated treatments that conflict with their values and needs, two Beth Israel Deaconess Medical Center physicians warn.

5 Aug 2009

Baxter completes production of batches of CELVAPAN A/H1N1 pandemic vaccine

Baxter International Inc. (NYSE: BAX) today announced that it completed production of its first commercial batches of CELVAPAN A/H1N1 pandemic vaccine in late July and is discussing plans for distribution with national health authorities, subject to obtaining appropriate authorizations. CELVAPAN, the brand name for the company’s A/H1N1 pandemic influenza vaccine, is made using Baxter’s proprietary Vero cell culture technology.

From Baxter International Inc. 5 Aug 2009

Epigenetic alterations may serve as markers for chronic leukemia

A new study shows that certain genes are turned off early, before clinical signs of the disease appear, in the development of chronic leukemia.

5 Aug 2009

Impax Labs receives FDA approval for generic version of Depakote

Impax Laboratories has confirmed that the U.S. Food and Drug Administration (FDA) has granted final approval of the Company’s Abbreviated New Drug Application (ANDA) for generic version of Depakote® (divalproex ER) 500mg Extended-release Tablets.

5 Aug 2009

New software for cochlear implants and hearing aids

Hearing aids and cochlear implants act as tiny amplifiers so the deaf and hard-of-hearing can make sense of voices and music. Unfortunately, these devices also amplify background sound, so they're less effective in a noisy environment like a busy workplace or cafe.

5 Aug 2009

Poll numbers show public wary of health reform legislation

"A Quinnipiac University poll released today suggests the public continues to be wary of health care legislation as members of Congress work through the August recess to sell President Obama's plan to voters," USA Today's On Politics blog reports (Fritze, 8/5).

5 Aug 2009

Cutting-edge imaging research aims to map brain injuries

In the first study of its kind, researchers at Saint Louis University are recruiting patients for a clinical trial that will use cutting-edge imaging equipment to map the brain injuries of combat veterans and civilians, aiming to better understand the nature of their injuries.

5 Aug 2009

Structure of an entire HIV genome decoded

The structure of an entire HIV genome has been decoded for the first time by researchers at the University of North Carolina at Chapel Hill. The results have widespread implications for understanding the strategies that viruses, like the one that causes AIDS, use to infect humans.

5 Aug 2009

Aptamers offer unique therapeutic advantages

A novel class of drugs composed of single strands of DNA or RNA, called aptamers, can bind protein targets with a high strength and specificity and are currently in clinical development as treatments for a broad range of common diseases, as described in a comprehensive review article published online ahead of print in Oligonucleotides.

5 Aug 2009

Baucus: Bipartisan group of finance committee members reach Medpac agreement

Senate Finance Chairman Max Baucus, D-Mont., said that a bipartisan group of six Finance Committee senators have "coalesced" around language "that would give new weight to the recommendations of an entity currently known as the Medicare Payment Advisory Commission, or MedPAC," Dow Jones reports.

5 Aug 2009

Obama: Healthcare reform bill to be passed by year end

During an Indiana speech on Wednesday, President Barack Obama said "there will be an overhaul of the health care system before the end of the year and said it doesn't have to be a bipartisan effort," according to The Associated Press. He also pledged that "successful conclusion of an ambitious health care overhaul that he has argued would stabilize the nation's fiscal health."

5 Aug 2009