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Mice predict the effectiveness of orally taken drugs

The amount of an orally taken drug that makes it to the site in the body at which it exerts its effects is much lower than the amount of an intravenously administered drug and it varies considerably between individuals.

2 Nov 2007

Medicaid pays for one-third of drug abuse hospitalizations

Medicaid paid for more than one-third of the 1.3 million hospital stays related to prescription or illegal drug abuse in 2005, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

2 Nov 2007

Discovery of novel mechanism to predict survival in older women with early stage lung cancer

A novel mechanism to predict survival in older women with early stage lung cancer has been uncoverecd by researchers at UCLA's Jonsson Comprehensive Cancer Center, a discovery that may have significant implications for new treatment approaches.

2 Nov 2007

Alexander Litvinenko poisoning caused limited public concern

The fatal poisoning of Alexander Litvinenko with radioactive polonium-210 in London in 2006 caused limited public concern about potential health risks, according to a study published on bmj.com.

2 Nov 2007

Link between sleep apnea and increased heart rate variability

A sleep-related breathing disorder, common in heart failure, increases one's heart rate variability.

2 Nov 2007

New evidence that psychological factors play a role in disease progression

Even though effective drug cocktails have improved the outlook for many patients with HIV, disease progression, including the time from AIDS onset to death, varies widely from patient to patient.

2 Nov 2007

Increased glucose level is a strong risk factor for colorectal cancer

Diabetes is a very common illness that affects more than 20 million people in the U.S. and it is estimated an additional 54 million Americans have pre-diabetes, a condition that occurs when a person's blood glucose levels are higher than normal but not high enough for a diagnosis of type 2 diabetes.

2 Nov 2007

Researchers find stem cells in degenerating spinal discs, potential for repair

Orthopedic researchers at Jefferson Medical College have for the first time found stem cells in the intervertebral discs of the human spine, suggesting that such cells might someday be used to help repair degenerating discs and remedy lower back and neck pain.

2 Nov 2007

Immune cell age plays role in retinal damage in age-related macular degeneration

Studying a mouse model of age-related macular degeneration, the leading cause of blindness in older Americans, scientists at Washington University School of Medicine in St. Louis have found age is key in determining whether damaging blood vessels will form beneath the retina and contribute to vision loss.

2 Nov 2007

Preventing Morphine tolerance

Tolerance to the pain-relieving effects of morphine - which builds rapidly with prolonged use - can be prevented by blocking a key substance that's formed when the drug is taken, researchers at the Saint Louis University School of Medicine have discovered.

2 Nov 2007

High-fat diet makes mice susceptible to liver injury

A high fat diet may kill regulatory T cells in the liver, allowing steatosis (simple fatty liver) to develop into steatohepatitis (fatty liver with inflammation), according to the results of a new study in the November issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD).

2 Nov 2007

Study looks at heart attack and acute angina patients in China

A survey of heart attack and acute angina patients in China has revealed that in many cases treatment is determined by financial considerations, not by the patients' potential for clinical benefit.

2 Nov 2007

Genes identified to protect brassicas from damaging disease

Scientists have identified a new way to breed brassicas, which include broccoli, cabbage and oilseed rape, resistant to a damaging virus.

2 Nov 2007

Femtosecond lasers to destroy blood-borne diseases like AIDS

Physicists in Arizona State University have designed a revolutionary laser technique which can destroy viruses and bacteria such as AIDS without damaging human cells and may also help reduce the spread of hospital infections such as MRSA.

2 Nov 2007

Supplements do not reduce cancer risk

Most experts agree that supplements add little, if anything, to a well-balanced diet.

2 Nov 2007

Panzem (2-methoxyestradiol ) drug a possible candidate for breast cancer treatment

A Mayo Clinic study of a drug that has shown promise in treating sarcoma, lung and brain cancers, demonstrates that the drug may also be effective in treating breast cancer, in particular the spread of breast cancer.

2 Nov 2007

New approach to medical nondisclosure

When family members ask physicians not to disclose bad news to ill loved ones, clinicians often struggle to balance their obligation to be truthful to the patient with the family's belief that the information would be harmful.

2 Nov 2007

Type 2 diabetes increasing throughout U.S.-Mexico border area

Diabetes has become the leading cause of death in Mexico and the third-leading cause of death among those living along the U.S. side of the border, health officials from the United States and Mexico said today in presenting the results of a new study coordinated by the Pan American Health Organization (PAHO).

2 Nov 2007

Indomethacin drug for stopping preterm labor may be harmful for babies

A drug commonly used to halt premature labor may be associated with brain damage and intestinal issues in premature babies, according to a new analysis of studies on the issue published today in American Journal of Obstetrics and Gynecology.

2 Nov 2007

Cutting-edge method that captures cell growth and activity

This month's issue of Cold Spring Harbor Protocols features a cutting-edge method that provides a snapshot of growth and activity patterns in mixed populations of cells. The protocol is freely accessible online.

2 Nov 2007