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Obesity and infertility in women

Obese women have alterations in their ovaries which might be responsible for an egg's inability to make an embryo, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

3 Mar 2009

Faulty signalling in the brain may cause schizophrenia

In the biggest study of its kind, scientists looking in detail at brain samples donated by people with the condition have identified 49 genes that work differently in the brains of schizophrenia patients compared to controls.

3 Mar 2009

Molecular switch linked to obesity, insulin resistance, type II diabetes

A molecular switch found in the fat tissue of obese mice is a critical factor in the development of insulin resistance, report scientists at the Salk Institute for Biological Studies.

3 Mar 2009

Protein function and chromatin structure methods featured in Cold Spring Harbor Protocols

Two new methods for analyzing the roles played by proteins in cells are featured in the March issue of Cold Spring Harbor Protocols.

3 Mar 2009

Best course of treatment to reduce risk of secondary stroke

Rush University Medical Center is participating in a National Institutes of Health (NIH) study to determine the best course of treatment to reduce the risk of stroke patients suffering another stroke.

3 Mar 2009

'Pre-diabetics' face heightened risk of heart disease

The study, published in the Journal of Clinical Endocrinology & Metabolism , was led by Jill P. Crandall, M.D., associate professor of clinical medicine and director of the Diabetes Clinical Trials Unit at Einstein.

3 Mar 2009

Pharmaxis announces NDA filing for Aridol

Pharmaxis, Inc., a wholly owned subsidiary of Pharmaxis Ltd , an emerging respiratory specialty pharmaceutical company, announced today that it has filed a New Drug Application (NDA), electronically, with the U.S. Food and Drug Administration (FDA) for Aridol (mannitol bronchial challenge test).

3 Mar 2009

Persistent Electronic Warnings Push Some Smokers to Quit

The more smokers worry about health risks, the more they will contemplate quitting, according to a new study in the latest issue of the journal Annals of Behavioral Medicine. Warning messages create worry that can nudge smokers down that road, the researchers concluded.

3 Mar 2009

Opioid antagonists help pain management

Achieving effective, durable, and safe pain relief, especially in patients with chronic and/or severe pain conditions, can be difficult.

3 Mar 2009

Hormone imbalance from obesity impacts sex life

Hormonal changes and diminished sexual quality of life among obese men are related to the degree of obesity, and both are improved after gastric bypass surgery according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

3 Mar 2009

Molecular test for cancer relapse in UK children

A molecular marker used in America to predict whether children with a form of kidney cancer, called Wilms' tumour, are more likely to relapse than other children, could be useful for UK patients.

3 Mar 2009

Missing link between fructose, insulin resistance found

A new study in mice sheds light on the insulin resistance that can come from diets loaded with high-fructose corn syrup, a sweetener found in most sodas and many other processed foods.

3 Mar 2009

Regular moderate alcohol intake associated with greater bone mineral density

Researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University found associations were strongest for beer and wine and, importantly, BMD was significantly lower in men drinking more than two servings of liquor per day.

3 Mar 2009

Trial looks at telmisartan in treating non-alcoholic steatohepatitis

Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are well-recognized causes of progressive liver disease leading to cirrhosis and hepatocellular carcinoma.

3 Mar 2009

Is esomeprazole the best choice for reflux esophagitis patients?

In patients with gastroesophageal reflux disease (GERD), esomeprazole, has demonstrated pharmacological and clinical benefits beyond those seen with the other proton pump inhibitors (PPIs).

3 Mar 2009

Insecticidal toxin useless without 'friendly' bacteria accomplices

The toxin produced by the bacterium Bacillus thuringiensis (Bt) is a popular insecticide used to control pest moths and butterflies, and in some GM pest-proof crops.

3 Mar 2009

Low energy density diet offsets influence of obesity gene

Children who carry a gene strongly associated with obesity could offset its effect by eating a low energy density diet, according to new research from UCL (University College London) and the University of Bristol published today in PLoS ONE.

3 Mar 2009

Inactivity of proteins behind longer shelf life when freezing

Frozen biological material, for example food, can be kept for a long time without perishing.

3 Mar 2009

Multiple childhood maltreatments lead to greater adolescent binge drinking

Researchers from Boston University found that multiple types of child maltreatment are robust risk factors for underage binge drinking based on a national multi-year study that explored the influence of social environment on the health of adolescents.

3 Mar 2009

Personality factors can influence the development of alcohol dependence

Researchers examined a group of AD individuals with the inactive form of aldehyde dehydrogenase-2 (ALDH2) - persons who would normally have a low incidence of alcoholism because the inactive form of ALDH2 causes flushing, nausea, and headaches. Results indicate that a strong need for novelty and little need for avoiding harm appear to increase the risk of AD.

3 Mar 2009