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New understanding of how anger can ventricular arrhythmias

New research published in the March 3, 2009, issue of the Journal of the American College of Cardiology finds that anger-induced electrical changes in the heart can predict future arrhythmias in patients with implantable cardioverter-defibrillators (ICDs).

23 Feb 2009

Aneurysms do not occur earlier in second generation

People whose parents or aunts and uncles have had a brain aneurysm are more likely to have one themselves, indicating that genetic risk factors passed down by generation are responsible.

23 Feb 2009

AIDS Healthcare Foundation launches "Stay Negative" HIV testing campaign

AIDS Healthcare Foundation (AHF) , which operates the largest community-based alternative HIV and sexually transmitted disease (STD) testing program in California, has launched an innovative and eye-catching Los Angeles-area HIV prevention and testing campaign urging the public to "Stay Negative" and to visit www.freehivtest.net to find out where to get tested quickly, conveniently and at no cost.

23 Feb 2009

CERAM offer medical device manufacturers key highlights to materials

CERAM, a global expert in medical device materials analysis, testing and consultancy, has published a white paper that highlights how critical a knowledge of materials and their characteristics is to the medical device manufacturer.

23 Feb 2009

Gold nanoparticles improve gene regulation

Investigators at Northwestern University have found that packing small interfering RNA (siRNA) molecules onto the surface of a gold nanoparticle can protect siRNAs from degradation and increase their ability to regulate genes involved in cancer. As a result of this discovery, cancer researchers have at their disposal a relatively straightforward method of delivering these potent gene-regulating agents into targeted cells.

23 Feb 2009

Targeted nanospheres find, penetrate, then fuel burning of melanoma

Hollow gold nanospheres equipped with a targeting peptide find melanoma cells, penetrate them deeply, and then cook the tumor when bathed with near-infrared light. When heated with lasers, the actively targeted hollow gold nanospheres did eight times more damage to melanoma tumors in mice than did the same nanospheres that gathered less directly in the tumors.

23 Feb 2009

Radiolabeled nanoparticles boost PET-CT combination imaging

In an attempt to decrease the amount of cancer-targeting nanoparticle needed to image tumors, a team of investigators at the Massachusetts General Hospital and Harvard Medical School has developed a simple method for creating iron oxide nanoparticles labeled with 18F, a radioisotope that is easily detected using positron emission tomography (PET). The result is a nanoparticle that can be imaged using PET, computerized tomography (CT), and fluorescence imaging.

23 Feb 2009

Nanoparticles detect dying cancer cells

Two years ago, researchers at the University of South Australia discovered a new molecular marker specific for chemotherapy-induced cancer cell death. Now, those same investigators have used this marker to develop an imaging agent that can pinpoint tumor cell death using magnetic resonance imaging.

23 Feb 2009

Microfluidic device mimics tumor microenvironment, helps drug discovery

One of the challenges that cancer researchers face in designing new antitumor agents is that of predicting how drug molecules will behave in the complex microenvironment that surrounds a tumor. In particular, tumors create all sorts of chemical and physical barriers that limit how much drug is able to enter a tumor, let alone reach cells deep within a tumor.

23 Feb 2009

New imaging techniques let scientists see biomolecules more clearly

Scientists have always wanted to take a closer look at biological systems and materials. From the magnifying glass to the electron microscope, they have developed increasingly sophisticated imaging devices.

23 Feb 2009

Basis of immunity to oral thrush, common in AIDS, identified by UB researchers

Oral thrush, a hallmark symptom in AIDS patients, is caused by a type of yeast that grows unchecked in people with weakened immune systems, and appears in colonies of white patches in the mouth.

23 Feb 2009

Statins can stimulate cardiac muscle cell regeneration, improve heart function

Statins, used widely to treat elevated cholesterol, have been shown to prevent progression of coronary narrowing and to have other beneficial effects on the heart, such as reducing inflammation, that are independent of cholesterol.

23 Feb 2009

Suppressing cancer with a master control gene

Starting with the tiny fruit fly and then moving into mice and humans, researchers at VIB and K. U. Leuven show that expression of the same gene suppresses cancer in all three organisms. Reciprocally, switching off the gene - called Ato in flies and ATOH1 in mammals - leads to cancer.

23 Feb 2009

Global AIDS Alliance sounds alarm on potential budget cuts

Amid initial indications that the administration's first budget will flat-line funding for global health, the Global AIDS Alliance is calling on President Obama, Vice President Biden and Secretary of State Hillary Clinton to keep their campaign commitments to scale up the President's Emergency Plan for AIDS Relief (PEPFAR) and accelerate efforts to ensure every child around the world gets a free basic education.

23 Feb 2009

Bavarian Nordic updates on breast cancer vaccine studies

Bavarian Nordic today provided updated data from its clinical studies with its breast cancer vaccine, MVA-BN(R)-HER2, in development as therapy of metastatic breast cancer patients whose tumours over-express HER2.

23 Feb 2009

Oxford Nanopore announces publication of DNA analysis paper

Oxford Nanopore Technologies ("Oxford Nanopore") today announced the publication of new research in Nature Nanotechnology, demonstrating accurate and continuous identification of DNA bases using nanopores.

From Oxford Nanopore Technologies 23 Feb 2009

Life-giving technology: Camera pills and ultrasound creating maps of the body

For more than ten years, senior medical officer Ronald Marvik at St. Olav's Hospital in Trondheim has been collaborating with SINTEF scientist Thomas Lango. Together, they have created a new IT-base window on the inside of the body, a window that makes a patient transparent on a screen when a surgeon inserts operating instruments through small openings in the abdominal wall.

23 Feb 2009