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Roche NimbleGen microarray technology enables highest-resolution map of human genome copy number variation

Roche NimbleGen's CGH microarray platform was used to generate the highest-resolution map of human genome copy number variation.

23 Jan 2009

Scientist decodes the language of memory cells

When an infection attacks, the body's immune system sounds the alert, kills the invading germs and remembers the pathogen to protect against contracting the same type of infection again.

23 Jan 2009

Researchers learn some of nicotine's secrets

Duke University Medical System researchers have discovered there are differing taste pathways for nicotine, which could provide a new approach for future smoking-cessation products.

23 Jan 2009

Inhaled corticosteroids reduces severity of asthma attacks in preschoolers

The largest study of its kind on preschoolers has demonstrated that preventive treatment with high doses of inhaled corticosteroids is effective in reducing the severity and duration of asthma attacks triggered by colds.

23 Jan 2009

New treatment for latent form of tuberculosis

Patients who are infected with the latent form of tuberculosis (TB) show no symptoms and are not contagious, yet they pose the biggest challenge when it comes to controlling the disease.

23 Jan 2009

Three new nomograms predict successful kidney transplant outcomes

Kidney transplants are the best available therapy for end stage renal disease.

23 Jan 2009

Drinking apple juice may delay onset of Alzheimer's disease

A growing body of evidence demonstrates that we can take steps to delay age-related cognitive decline, including in some cases that which accompanies Alzheimer's disease, according to a study published in the January 2009 issue of the Journal of Alzheimer's Disease.

23 Jan 2009

Researchers create precise biosensor for detecting blood glucose

Researchers have created a precise biosensor for detecting blood glucose and potentially many other biological molecules by using hollow structures called single-wall carbon nanotubes anchored to gold-coated "nanocubes."

23 Jan 2009

Advances in metagenomics

In an upcoming issue of Proceedings of the National Academy of Sciences , Yale researchers used newly developed mathematical models to analyze huge amounts of data on physical characteristics such as temperature and salinity in different ocean habitats and metabolic activity in marine micro-organisms.

23 Jan 2009

Low-carb diet burns more excess liver fat than low-cal diet

People on low-carbohydrate diets are more dependent on the oxidation of fat in the liver for energy than those on a low-calorie diet, researchers at UT Southwestern Medical Center have found in a small clinical study.

23 Jan 2009

Leaky membranes: Another sign of old age

As parts of us age, even the membrane bound nuclei , which house the genetic instructions for life that are "written" in our DNA, begin to show considerable wear and tear, suggests a new report in the January 23rd issue of the journal Cell, a Cell Press publication.

23 Jan 2009

Discovery of key protein regulator of inflammation and cell death

Reporting in the journal Nature , researchers led by Emad Alnemri, Ph.D., professor of Biochemistry and Molecular Biology in the Kimmel Cancer Center at Jefferson, discovered a key protein component involved in inflammation.

23 Jan 2009

Inflammation worsens danger due to atherosclerosis

Current research suggests that inflammation increases the risk of plaque rupture in atherosclerosis.

23 Jan 2009

Implants mimic infection to rally immune system against tumors

Bioengineers at Harvard University have shown that small plastic disks impregnated with tumor-specific antigens and implanted under the skin can reprogram the mammalian immune system to attack tumors.

23 Jan 2009

Healthcare will be a headache for Obama

Among industrialised nations, the US spends well over twice the per capita average on health care and soaring health costs are expected to reach 20 per cent of Gross Domestic Product by 2015.

23 Jan 2009

Genetic interactions are the key to understanding complex traits

In recent years, genetic studies have uncovered hundreds of DNA variations linked to common diseases, such as cancer or diabetes, raising the prospect that scientists can gauge disease risk based on information in an individual's genome.

23 Jan 2009

Gene provides hope for restoring injured nerves

University of Utah scientists identified a worm gene that is essential for damaged nerve cells to regenerate, and showed they could speed nerve regeneration by over-activating the gene - a step toward new treatments for nerves injured by trauma or disease

23 Jan 2009

First '3D movie' of tumour protein gives new drug hope

First '3D movie' of tumour protein gives new drug hope CANCER RESEARCH UK scientists have created the first complete model of a molecule which captains a key cell signalling network to prevent cancer - and exposed the secret of how a highly selective drug can intervene to control its activity, according to a study published in PLoS Biology.

23 Jan 2009

Lisofylline drug improves type 2 insulin action; reduces harm of fat in preclinical study

Results of a preclinical study involving DiaKine Therapeutics' lead drug candidate Lisofylline (LSF) indicate the compound may reduce two key risk factors for type 2 diabetes.

23 Jan 2009

Morbidity rates increased substantially after Hurricane Katrina

In the year following Hurricane Katrina, the health of survivors 65 and over declined nearly 4 times that of a national sample of older adults not affected by the disaster, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

23 Jan 2009