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First-ever international guidelines for the treatment of psoriatic arthritis

Rheumatologists, dermatologists, and patient advocates have come together to publish the first-ever international guidelines for the treatment of psoriatic arthritis, a disease that mainly affects people who have psoriasis but also some people without it.

26 Oct 2008

Gardasil safety questioned, CDC urged to back up statement with data

The National Vaccine Information Center (NVIC) is calling on the Centers for Disease Control (CDC) and Food and Drug Administration (FDA) to publicly release the study design, data and names of principal investigators involved in a statement this week maintaining that Gardasil vaccine is safe with no serious side effects.

26 Oct 2008

Targanta Therapeutics presents preclinical data on Oritavancin against Clostridium difficile infection

Targanta Therapeutics Corporation has released the in vivo data from a preclinical study comparing the activity of its antibiotic drug candidate, oritavancin, to vancomycin in a hamster model of Clostridium difficile infection.

26 Oct 2008

Kamada completes final analysis of phase III trial with intravenous Alpha-1 Antitrypsin (AAT), for hereditary AAT deficiency

Kamada has announced that it has completed the final analysis of its US Phase III trial with intravenous Alpha-1 Antitrypsin (AAT), for hereditary AAT deficiency.

26 Oct 2008

Human rhinovirus found to manipulate genes

Sneezing, runny nose and chills? You might blame the human rhinovirus (HRV), which causes 30 to 50 percent of common colds. But in reality, it's not the virus itself but HRV's ability to manipulate your genes that is the true cause of some of the most annoying cold symptoms.

26 Oct 2008

Simple gene-based blood test, quicker, more accurate evaluation for cystic fibrosis

Researchers at National Jewish Health have identified a simple gene-based blood test that more accurately and quickly measures cystic fibrosis patients' response to therapy than current tests.

26 Oct 2008

Gates Foundation grant to help prevent deaths in Africa by improving antibiotic access

The Alliance for the Prudent Use of Antibiotics (APUA) has announced a $1.37 million grant from the Bill & Melinda Gates Foundation, to explore ways of reducing millions of preventable deaths from severe respiratory and diarrheal infections in Africa. This project was announced in conjunction with a colloquium at the annual ICAAC/IDSA meeting warning of increasing antibiotic resistance.

26 Oct 2008

Even minimally symptomatic obstructive sleep apnea increases cardiovascular risk

People with even minimally symptomatic obstructive sleep apnea (OSA) may be at increased risk for cardiovascular disease because of impaired endothelial function and increased arterial stiffness, according to a study from the Oxford Centre for Respiratory Medicine in the UK.

26 Oct 2008

High dose flu vaccine boosts immune response in elderly

Giving people age 65 and older a dose four times larger than the standard flu vaccine boosts the amount of antibodies in their blood to levels considered protective against the flu, more so than the standard flu vaccine does. The findings from a study of nearly 4,000 people were presented Oct. 26 at a national meeting on infectious diseases.

26 Oct 2008

Genetically modified tomatoes rich in anthocyanins

Researchers from the John Innes Centre in Norwich, Great Britain, in collaboration with other European centres participating to the FLORA project, have obtained genetically modified tomatoes rich in anthocyanins, a category of antioxidants belonging to the class of flavonoids. These tomatoes, added to the diet of cancer-prone mice, showed a significant protective effect by extending the mice lifespan. The research has been published in the 26 October issue of Nature Biotechnology.

26 Oct 2008

FDA approves lung valve to control some air leaks post-surgery

The U.S. Food and Drug Administration has approved an implantable and removable valve system designed to control some air leaks in the lungs that persist after certain kinds of lung surgery.

26 Oct 2008

Life in Canada more deadly for immigrants?

Immigrants who come to Canada seeking a better life may in fact be setting themselves up for possible premature death.

26 Oct 2008

Sensitive ultrasound to spot early-stage cancer

European researchers have developed highly sensitive ultrasound equipment that can detect tiny quantities of reflective microbubbles engineered to stick to specific tumour cells. The technique should pick up tumours early and improve patients' chances of survival.

26 Oct 2008

Newly discovered mechanism can explain the Beckwith-Wiedemann syndrome

Researchers from Uppsala University have discovered a mechanism that silences several genes in a chromosome domain. The findings, published in today's on-line issue of Molecular Cell, have implications in understanding the human disorder Beckwith-Wiedemann syndrome.

26 Oct 2008

Advancing medical research

Researchers from the University of Essex and medical counterparts from Colchester Hospital University NHS Foundation Trust are working together to develop successful partnerships in advancing medical research.

26 Oct 2008

New molecules with many branches will help unleash potential of nanotechnology

Materials science and the pharmaceutical industry could soon be revolutionized by emerging nanotechnologies based on designer molecules with long complex tree-and branch structures. Such molecules offer almost limitless scope for design of bespoke compounds for specific applications in disease therapy, for novel materials such as resins, as well as electronic displays, and energy storage. Almost every field involving design and synthesis of chemical compounds will be transformed by the arrival of technologies allowing nanoscale design of these branched molecules, known as hyperbranched polymers.

26 Oct 2008

Scientists discover how a well-known protein repairs broken DNA ends

During the life cycle of our cells, a minefield of environmental and biological assaults can lead to double-stranded DNA breaks, the most lethal and dangerous form of DNA damage. Now, in research published online this week in Nature, Rockefeller University scientists reveal that when these breaks occur, a protein called 53BP1 helps repair them by mobilizing their dangly DNA ends - findings that uncover a previously unknown aspect of how double-stranded breaks can get fixed.

26 Oct 2008

A new role for a critical DNA repair molecule in the immune system

The human immune system is a brilliantly adaptable weapon against foreign invaders. But it all depends on the work of specialized cells called lymphocytes that have made a risky evolutionary gambit to mutate their own DNA.

26 Oct 2008

Breastfeeding and breast sagging, shape

Findings from a study published in the September/October 2008 issue of the Aesthetic Surgery Journal show that, contrary to popular belief, breastfeeding is not a likely cause of post-pregnancy drooping of the breasts.

23 Oct 2008

NanoVibronix receives FDA clearance for PainShield diathermy device

NanoVibronix, a medical device company, announced that the US Food and Drug Administration (FDA) has granted 510K clearance to market PainShield MD, a diathermy device used to treat pain. PainShield is the first hands-free, patch-based diathermy device, thus allowing for an entirely new dimension in ultrasound treatment of pain and soft tissue healing. The PainShield consists of a disposable patch connected to a portable reusable driver and generates ultrasound waves to the desired area of the body.

23 Oct 2008