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Researchers identify immune dysfunction in melanoma patients

Researchers at the Stanford University School of Medicine have begun to shed light on why the human immune system isn't able to stop such cancers as melanoma, suggesting answers that could pave the way for better treatment of this often-fatal illness.

9 May 2007

Sigma-Aldrich acquires Molecular Medicine BioServices

Sigma-Aldrich Corporation has announced that it has acquired Molecular Medicine BioServices Inc. (MMB), a biopharmaceutical contract manufacturing organization (CMO) located in Carlsbad, California, to further enhance the biologics capabilities within its SAFC Pharma business segment.

9 May 2007

Cancer screening in women: BMI and adherence to physician recommendations

While severe obesity can be accompanied by other health problems including cancer, severely obese women are likely to skip clinical breast exams, mammograms and Pap smears, according to a recent analysis.

9 May 2007

Rosuvastatin well tolerated by a broad range of patients with dyslipidemia

The safety and tolerability of rosuvastatin were assessed using data from 16,876 patients who received rosuvastatin 5-40 mg in a multinational phase II/III/IIIb/IV program, representing 25,670 patient-years of continuous exposure to rosuvastatin. An integrated database, consisting of 33 trials whose databases were locked up to and including September 16, 2005, was used to examine adverse events and laboratory data.

9 May 2007

Pediatric interventions at 1 to 3 age may have the greatest impact at preventing childhood obesity

Columbia researchers have uncovered a critical age when many inner city children become overweight or obese: between the ages of 1 and 3 years old.

9 May 2007

Researchers develop first antibody that detects gene mutations that cause amyotrophic lateral sclerosis

Researchers at the University of Toronto's Faculty of Medicine have developed the first antibody that detects the only known cause of amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease.

9 May 2007

Males have evolved to deliver sperm more effectively to females with multiple partners

A review of the latest research in sexual adaptation shows that evidence is building for what researchers call "sperm competition."

9 May 2007

The influence of diluent warming on dantrolene sodium mixing time

Every second counts for anesthesia patients afflicted by the often deadly condition known as malignant hyperthermia (MH).

9 May 2007

Study finds collective bargaining rights for independent pharmacists could cost Medicare and commercial payors $29.6 billion over five years

A key legislative priority championed by the independent drugstore lobby, HR 971, that would provide pharmacists with new, sweeping collective bargaining rights could increase prescription drug costs for Medicare and commercial payors by 11.8 percent, or $29.6 billion, over five years, according to a new analysis from CRA International released by the Pharmaceutical Care Management Association (PCMA).

9 May 2007

Off-label and untested use of drug-coated stents is common in U.S. practice

The off-label and untested use of drug-coated stents in the treatment of coronary artery blockage is common in U.S. practice, and ischemic complication rates are higher among patients receiving drug-coated stents for off-label indications, according to two studies in the May 9 issue of Journal of the American Medical Association.

9 May 2007

Impact of the nurse shortage on hospital patient care

Physicians, nurses and hospital administrators voice their concerns about the nursing shortage in a new study by Peter Buerhaus, Ph.D., professor of Nursing at Vanderbilt University and director of the Center for Interdisciplinary Workforce Studies at the Medical Center.

9 May 2007

It is highly unlikely that older women generate new eggs

Tilly reported the discovery of stem cells capable of migrating from bone marrow to mouse ovaries and generating new eggs there. The research fueled hopes that a new treatment - such as bone marrow transplantation - might one day help older women regain their fertility.

9 May 2007

Adverse outcomes associated with unapproved uses of drug-coated stents

Research led by a team at the Methodist DeBakey Heart Center sheds light on what happens to high-risk patients who receive drug-coated stents off-label to open clogged arteries, as reported in today's Journal of the American Medical Association (JAMA) .

9 May 2007

Research sheds light on memory by erasing it

For years, scientists have studied the molecular basis of memory storage, trying to find the molecules that store memory, just as DNA stores genetic memory.

9 May 2007

Attention training is worth examining for disorders with attentional components, like ADHD

Everyday experience and psychology research both indicate that paying close attention to one thing can keep you from noticing something else.

9 May 2007

Medicis Pharmaceutical to resolve false claims allegations

Medicis Pharmaceutical Corporation of Scottsdale, Ariz., will pay the United States $9.8 million to settle allegations that the company violated the False Claims Act with respect to claims submitted to Medicaid, the Justice Department announced.

9 May 2007

Promoting health in teens and kids

Early results of a program aimed at combating childhood obesity show promise and the program is being well received by the children and their families.

9 May 2007

Hepatitis C infection is associated with an increased risk of non-Hodgkin lymphoma

Hepatitis C infection is associated with an increased risk of non-Hodgkin lymphoma (malignancy involving lymphatic tissue) of 20 percent to 30 percent, and a three-fold increase in the risk of another type of lymphoma, according to a study in the May 9 issue of JAMA.

9 May 2007

Global heartbeat control suggests therapy for beating heart failure

Keeping a healthy heart beating requires the production of a constant supply of energy, a feat depending on the coordination of several genetic programs.

9 May 2007

Genetics of bipolar disorder

The likelihood of developing bipolar disorder depends in part on the combined, small effects of variations in many different genes in the brain, none of which is powerful enough to cause the disease by itself, a new study shows.

9 May 2007