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Fluoride toothpaste too pricey for world's poorest people

Fluoride toothpaste is prohibitively expensive for the world's poorest people, according to a study published in BioMed Central's open access journal Globalization and Health. Researchers revealed that the poorest populations of developing countries have the least access to affordable toothpaste.

15 Jun 2008

Biological medicine helps more people with rheumatoid arthritis

Patients who have recently developed rheumatoid arthritis respond better to treatment with biological medicine in combination with conventional pharmacological medicine. This according to results of the Swefot national clinical study, which is to be presented at an international rheumatology congress in Paris by scientists from Swedish Karolinska Institutet and Karolinska University Hospital, who conducted the study in association with another 15 rheumatology units in Sweden.

15 Jun 2008

New medical equipment tested to extremes

New medical equipment recently delivered to the Antarctic station Concordia will help understand how our bodies physically adapt to this extreme environment - knowledge which could help prepare for a future human mission to Mars. ESA is currently looking for a candidate with a medical background to support projects at the research base.

15 Jun 2008

How to reduce obesity and cardiovascular disease risk

Changes in society are leading to a sedentary lifestyle and are causing a rise in the number of people with obesity and cardiovascular disease. This is consequently having a large impact on the health of the nation.

15 Jun 2008

EUROACTION Trial: A comprehensive approach to cardiovascular prevention

The single largest research project ever to be undertaken by the European Society of Cardiology (ESC), EUROACTION, showed that a multidisciplinary, family based and nurse coordinated programme made a real difference in improving lifestyle and reducing cardiovascular risk among coronary patients and people with a high risk of developing Cardiovascular Disease (CVD).

15 Jun 2008

European researchers take lid off the genome

European researchers have made significant progress unravelling how genes are governed and why this sometimes goes wrong in disease.

15 Jun 2008

Transfer of learning traced to areas of the brain

Practice makes perfect, but a question that still remains a mystery is why it is so difficult to transfer learning from a trained to an untrained task? Why are we no better at remembering faces when we have been training our memory for words? Scientists at Umea University and Karolinska Institutet in Sweden now show in the journal Science that the answer lies in the brain areas activated by each task.

15 Jun 2008

Integrated control of malaria and other vector diseases is crucial

Combating malaria and other so-called vector diseases with chemical controls is increasingly ineffective, besides being hazardous for humans and the environment. These chemical controls must therefore be eliminated. In order to combat the diseases that insects and ticks transmit, all possible strategies must be united.

15 Jun 2008

Asian women and incontinence

Urinary incontinence is an important health problem affecting an estimated 5 million women in the UK.

15 Jun 2008

New treatment for Obsessive Compulsive Disorder

A new treatment for Obsessive Compulsive Disorder (OCD) pioneered at the University of Sydney is having great success by targeting the beliefs behind the obsessive behaviour rather than the behaviour itself.

15 Jun 2008

Women, Latinos face higher brain aneurysm risk

A type of stroke that can strike at any age, and kills one-third of its victims, appears to be more common in women and Mexican-Americans than in non-Hispanic white men, according to a new study from the University of Michigan Stroke Program.

15 Jun 2008

Collaborative effort by FDA and EMEA expected to yield additional safety data when assessing new drugs

In the first use of a framework allowing submission of a single application to the two agencies, the Food and Drug Administration (FDA) and the European Medicines Agency (EMEA) worked together to allow drug companies to submit the results of seven new tests that evaluate kidney damage during animal studies of new drugs. The tests measure the levels of seven key proteins or "biomarkers" found in urine that can provide additional information about drug-induced damage to kidney cells, also known as renal toxicity.

15 Jun 2008

Nanoparticles trigger built-in cell-death signal to overcome drug resistance

One of the most vexing problems in treating cancer is the propensity of tumors to develop resistance to a wide range of anticancer drugs. Over 70 percent of ovarian cancer patients, for example, have drug-resistant tumors at the time of their initial diagnosis, and virtually all patients who relapse have drug-resistant tumors.

15 Jun 2008

High-content screening as a universal tool for fingerprinting of vytotoxicity of nanoparticles

As researchers develop an ever-expanding toolkit of nanoparticles for use as drug and imaging agent delivery vehicles, there is a growing need to understand how a given nanoparticle's physical and chemical properties affect biological activity and toxicity.

15 Jun 2008

Nanoparticle delivers antisense agent to tumors

A multifunctional drug delivery system consisting of a lipid-based nanoparticle, a standard anticancer drug, and a short nucleic acid designed to augment the activity of that drug has demonstrated the ability to treat drug-resistant tumor cells.

15 Jun 2008

Cancer-detecting nanoparticles

Magnetic resonance imaging (MRI) can be a doctor's best friend for detecting a tumor in the body without resorting to surgery. MRI scans use pulses of magnetic waves and gauge the return signals to identify different types of tissue in the body, distinguishing bone from muscle, fluids from solids, and so on.

15 Jun 2008

Human tumor nanoparticles induce apoptosis of pancreatic cancer cells

Using nanoparticles made from pieces of tumor cells, investigators from Aix-Marseille University in Marseille, France, have developed a new type of anticancer agent that appears to stop tumor cell growth and proliferation.

15 Jun 2008

Targeted quantum rods probe blood-brain barrier

One of the chief difficulties in treating brain tumors involves getting potential tumor-killing drugs across the blood-brain barrier and into the brain.

15 Jun 2008

Discovery of mechanism that prevents cells from transforming into cancer cells

MRC scientists have discovered a mechanism that prevents cells from transforming into cancer cells. As cells age they enter a state called senescence, a kind of suspended animation that allows a cell to keep functioning but prevents it from changing. This state can also be triggered by what's called an 'insult' to the cell, for example a signal from a cancer-initiating gene.

15 Jun 2008

New technique provides greater understanding of how drugs get in and out of cells in our bodies

A team led by female scientists at the Universities of Bristol and Cambridge has developed an exciting new technique which may lead to a greater understanding of how drugs get in and out of the cells in our bodies. The method identifies the structures that guard the entrance and exits to cells.

15 Jun 2008