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New cancer stem cell identified behind metastatic tumors

The molecular profile of cancer stem cells that initiate metastatic colon tumors is significantly different from those responsible for primary tumors, according to new research from a team at Weill Cornell Medical College.

28 May 2008

Novel approach to drug insolubility strengthens PolyTherics patent estate

Polytherics Ltd, a biopharmaceutical spin-out company from Imperial College London and the London School of Pharmacy that specialises in the targeted application of polymers to biopharmaceuticals, has announced the grant of a European patent on the application of polymer complexation technology to improve drug efficacy.

28 May 2008

Estrogen drives distinct, aggressive prostate cancer

Using a breakthrough technology, researchers led by a Weill Cornell Medical College scientist have pinpointed the hormone estrogen as a key player in about half of all prostate cancers.

28 May 2008

Medical errors - Is healthcare getting worse or better?

Most would say worse. And one of the many reasons is medical errors. Most Americans say the quality of care has not improved, and dissatisfaction among patients and caregivers has increased. The perceptions exist despite the efforts across the country to reduce medical errors.

28 May 2008

Cancer Research UK creates 'crack teams' to solve cancer's greatest mysteries

World leading scientists are to be targeted by Cancer Research UK and its development and commercialisation arm Cancer Research Technology (CRT), in an effort to tackle some of cancer's most pressing scientific challenges.

28 May 2008

FDA proposes major revisions to the physician labeling for prescription drugs

The U.S. Food and Drug Administration today proposed major revisions to the physician labeling for prescription drugs (including biological products) to provide better information about the effects of medicines used during pregnancy and breast-feeding.

28 May 2008

Scientists identify a brain mechanism underlying persistent cocaine craving

Scientists have identified a mechanism in the brain that helps to explain why craving for cocaine, and the risk of relapse, seems to increase in the weeks and months after drug use is stopped. The research was supported by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health.

28 May 2008

New multi-million pound study to find the cause of Type 1 diabetes

Juvenile Diabetes Research Foundation (JDRF) has awarded more than £3 million to fund a research centre that will investigate the causes of Type 1 diabetes - a condition that results from an immune attack on the body's insulin producing cells. The study, known as the JDRF Centre for Diabetes Genes, Autoimmunity and Prevention (D-GAP), aims to understand how and why Type 1 diabetes occurs, knowledge that may help develop future therapies with the aim of preventing the condition.

28 May 2008

Why some treatments rescue aging skin

Fine wrinkles, deeper creases, saggy areas around the mouth and neck - the sights in the mirror that make baby boomers wince - are not inevitable. They result from a structural breakdown inside the skin that some existing treatments effectively counteract by stimulating the growth of new, youthful collagen, University of Michigan scientists say.

28 May 2008

Allergy - it's in the genes

In a world first scientists at theWestmead Millennium Institute have identified how a gene associated with allergic diseases such as asthma and eczema works, providing new hope for potential drug treatments.

28 May 2008

Scientists sequence first female DNA

Geneticists of Leiden University Medical Centre (LUMC) are the first to determine the DNA sequence of a woman. She is also the first European whose DNA sequence has been determined. This has been announced by the researchers this morning, during a special press conference at 'Bessensap', a yearly meeting of scientists and the press in the Netherlands.

27 May 2008

Netherlands bears part of the costs of ageing in other EU countries

Countries in the European Union with fully funded pension schemes, such as the Netherlands, will in the long term bear part of the burden of an ageing population in countries operating a pay-as-you-go (PAYG) system.

27 May 2008

Global drug research programme comes to Diamond in Oxfordshire

Diamond has announced that USA-based global biotechnology company Vertex Pharmaceuticals Incorporated is the first industrial user at the UK's world class new research facility, Diamond Light Source

27 May 2008

febit receives U.S. patent for microfluidic extraction method

febit today announced the receipt of US patent #7320862 on its microfluidic microarray-based method for extraction of DNA and RNA.

27 May 2008

First patient enrolled in phase III study of Bevacizumab and Trastuzumab in early breast cancer

A new international study for women with HER2-positive breast cancer is open for enrollment. The pivotal BETH (BEvacizumab and Trastuzumab Adjuvant Therapy in HER2-positive Breast Cancer) study is a Phase III clinical research trial that is investigating the benefits of combining two monoclonal antibodies, the anti-angiogenic, bevacizumab (Avastin) and the targeted therapy trastuzumab (Herceptin), together with chemotherapy for the treatment of patients with early stage HER2-positive breast cancer.

27 May 2008

Barr confirms Entocort patent challenge

Barr Pharmaceuticals, Inc. today confirmed that its subsidiary, Barr Laboratories, Inc., has initiated a challenge of the patents listed by AstraZeneca LP in connection with its Entocort(R) Enteric Coated Capsules (budesonide), 3mg.

27 May 2008

Patients to benefit from multi-million pound research funding

NHS patients in North West London will benefit from a multi-million pound research project leading to the rapid introduction of new, effective treatments for a wide range of medical conditions.

27 May 2008

Digital Healthcare appointed to major NHS Framework contract

NHS Connecting for Health, on behalf of the NHS, has appointed Digital Healthcare to the NHS Additional Supply Capability & Capacity (ASCC) Framework following open competition bids to provide additional capacity and capability in the supply of IT products and services to the NHS.

27 May 2008

Nurse-midwives present blankets for babies to Boston area women's organizations

Women, newborns, and families in the Boston area will benefit from the contributions of new and handmade blankets during the American College of Nurse-Midwives (ACNM) annual Blankets for Babies public service campaign during the ACNM 53rd Annual Meeting & Exhibit in Boston. Three area women's organizations will receive baby blankets, which are donated by certified nurse-midwives, certified midwives, student nurse-midwives, exhibitors and other meeting guests.

27 May 2008

Avoiding spleen removal for Cooley's anemia sufferers

Researchers from Weill Cornell Medical College may have discovered the precise role of a gene in one of the world's most common blood disorders, beta-thalassemia, commonly known as Cooley's anemia. Along with sickle-cell anemia, Cooley's anemia is the most commonly inherited disease in the world, affecting many people of Mediterranean descent, and 20 out of every 100,000 African-Americans. The World Health Organization estimates that between 50,000-100,000 children are born with the disease each year.

27 May 2008