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Cethromycin achieves all endpoints in second pivotal Phase III Trial for treatment for pneumonia

Advanced Life Sciences Holdings, Inc. (Nasdaq: ADLS), today announced positive results from Trial CL-05, the second of two pivotal phase III clinical trials designed to assess the safety and effectiveness of cethromycin, a novel once-a-day oral antibiotic for the treatment of mild-to-moderate community acquired pneumonia (CAP), the sixth leading cause of death in the United States.

16 Nov 2007

CD200 stifles anti-tumor immunity

The prognosis for individuals with metastatic melanoma (MM) is not good. Therapeutic strategies to enhance the immune response have some clinical benefit; however, most patients eventually succumb to progressive disease, in part because their immune cells known as dendritic cells (DCs) fail to sustain an effective antitumor T cell immune response.

16 Nov 2007

New computational theory of brain function

Carnegie Mellon University neuroscientist Marcel Just and Stanford postdoctoral fellow Sashank Varma have put forward a new computational theory of brain function that provides answers to one of the central questions of modern science:

16 Nov 2007

Brain compensatory mechanisms contribute to recovery from spinal cord injury

A research team led by Tadashi Isa, a professor at the Japanese National Institute for Physiological Sciences, NIPS (SEIRIKEN), and Dr. Yukio Nishimura (University of Washington, Seattle), have found that brain compensatory mechanisms contribute to recovery from spinal cord injury.

16 Nov 2007

Biomarkers for Alzheimer's can be trusted in clinical trials

The best-established biomarkers for Alzheimer’s disease have a low natural variation over two years. The results speak for the inclusion of these biomarkers in clinical trials of novel drugs against Alzheimer’s disease.

16 Nov 2007

University of Delaware research to shed light on osteoporosis

Ten million people in the United States are estimated to already have bone diseases, and almost 34 million more are estimated to have low bone mass, putting them at increased risk for osteoporosis, according to the National Osteoporosis Foundation.

16 Nov 2007

New guidelines for ureteral stone management

The American Urological Association (AUA) is pleased to announce the release of a new Guideline for the Management of Ureteral Calculi prepared as a collaborative effort with the European Association of Urology (EAU).

16 Nov 2007

Asthma education brochures aimed at minorities miss the mark in Wisconsin

A Wisconsin study found that take-home educational materials designed for the state's minority children with asthma do not adequately address the cultural and linguistic issues unique to racial/ethnic minority groups.

16 Nov 2007

Nasty new cold virus claims lives across the U.S.

A nasty new version of the virus which causes the common cold is spreading across the United States.

15 Nov 2007

Stem cells from cloned monkeys - a breakthrough or an ethical nightmare?

In an important breakthrough scientists in the United States have cloned monkey embryos to create embryonic stem cells.

15 Nov 2007

Drug to treat children with bipolar disorder gets priority review

An anti-psychotic drug already approved in the U.S. to treat adults and adolescents with schizophrenia may soon be available for youngsters age 10 to 17 years of age suffering from bipolar disorder.

15 Nov 2007

British charity says protect children and ban tobacco vending machines

A British charity has called for a ban on tobacco vending machines in order to protect children from the harmful effects of smoking.

15 Nov 2007

Experts say obese women should be refused fertility treatment

A fertility organisation in Britain is saying that severely obese women should be barred from having National Health Service fertility treatment until they have lost weight.

15 Nov 2007

Curvy women have the edge on their skinny sisters

According to American researchers curvaceous women may have the edge on their skinny sisters in more ways than one.

15 Nov 2007

Christmas is coming and so is bird flu!

It is feared that tens of thousands of turkeys will be slaughtered across Britain in efforts to contain the spread of the deadly H5N1 bird flu.

15 Nov 2007

Risks of cosmetic surgery under the spotlight again

The safety of cosmetic surgery has again become an issue following the death of the mother of rapper Kanye West.

15 Nov 2007

Top selling diabetes drug to carry back box warning

The government watchdog body in the U.S., The Food and Drug Administration (FDA), has placed a "black box" warning on the popular drug Avandia.

15 Nov 2007

Diet rich in omega-3 oils, fruit, veggies and fish protects against dementia

According to a new study by French researchers a diet which is rich in omega-3 oils, fruit and vegetables as well as fish may reduce the risk of dementia in elderly people.

15 Nov 2007

YKL-40 protein may play a role in severe asthma

A protein measured in a simple blood test may be a new biomarker to identify patients with the most serious form of asthma, Yale School of Medicine researchers report in the New England Journal of Medicine.

15 Nov 2007

Viral infection affects important cells' stress response

Viral infection disrupts the normal response of mammalian cells to outside deleterious forces, cleaving and inactivating a protein called G3BP that helps drive the formation of stress granules, which shelter the messenger RNAs that carry the code for protein formation, said researchers from Baylor College of Medicine in Houston.

15 Nov 2007