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Isis Pharmaceuticals awarded $1.5 million NIH grant to improve RNAi-based therapeutics

Isis Pharmaceuticals, Inc. has announced that it has been awarded a multi-year Phase 2 Small Business Innovation Research (SBIR) grant by the National Institutes of Health (NIH) for up to $1.5 million to design oligonucleotide drugs that can exploit the RNA interference (RNAi) antisense mechanism for disease treatment.

4 Oct 2007

Gene-chip studies provide new leads in treating abnormal lung development in premature newborns

Some 20 to 40 percent of extremely premature infants suffer abnormal lung development leading to bronchopulmonary dysplasia, a chronic lung disease that can cause long-term breathing problems.

4 Oct 2007

Choosing the best treatment for disease

The diagnosis has come in, and it's not good. Worse, the patient has to choose from treatment options that are sometimes contradictory and risky.

4 Oct 2007

PAZAR - virtual bazaar of gene regulation data

An international team has opened a virtual bazaar, called PAZAR, which allows biologists to share information about gene regulation through individually managed 'boutiques' (data collections).

4 Oct 2007

FDA tightens potency specifications to ensure thyroid drugs last

The U.S. Food and Drug Administration is tightening the potency specifications for levothyroxine sodium, used to treat underactive thyroid glands and other thyroid conditions, to ensure the drug retains its potency over its entire shelf life.

4 Oct 2007

Learning from the Toronto SARS outbreak

Locked doors, full masks and gowns, questionnaires and line-ups at the hand washing stations - getting health-care services during SARS wasn't easy.

4 Oct 2007

Large gap between physician and patient understanding of necessity of monthly periods

More than the two thirds of the women in a national survey say that they are interested in suppressing their menstrual periods but many of them aren't sure if it's safe.

4 Oct 2007

Vaccine combo okay for infants

A University of Rochester study brings relief to new parents who, while navigating a jam-packed childhood vaccine schedule, can expect to soothe their newborn through as many as 15 “pokes” by his or her six-month checkup.

4 Oct 2007

Renewed search for lupus treatments and cure

For the first time in decades, a significant number of clinical trials are being conducted to seek a treatment, perhaps even a cure, for lupus, a chronic and potentially fatal autoimmune disease that affects more than 1.5 million Americans -- 10,000 in Los Angeles County alone.

4 Oct 2007

Brain processes identified in humans' behavioral response to threat of punishment

Researchers have identified brain structures that process the threat of punishment for violating social norms.

4 Oct 2007

Brain needs perfection in synapse number

Like Goldilocks, the brain seeks proportions that are just right. The proper number of synapses or communication between nerve cells, determined early in life, is crucial to having a healthy brain that can learn and retain information.

4 Oct 2007

American College of Physicians recommends annual influenza vaccine for health-care workers

The American College of Physicians (ACP) recommends that an annual influenza vaccine should be required for every health care worker with direct patient care activities.

4 Oct 2007

AACAP reaction to S-CHIP Veto

The American Academy of Child and Adolescent Psychiatry strongly urges Congress to override President Bush's veto of the State Children's Health Insurance Program (H.R. 976) act.

4 Oct 2007

Americans strongly desire a well-coordinated trauma system

Americans may be sharply divided in their views on many aspects of health care in the United States, but they are in strong agreement when it comes to one of the most important but overlooked elements - a nationwide trauma system.

4 Oct 2007

New understanding of how brain controls blood pressure regulation

A discovery made 25 years ago about how the brain controls blood pressure regulation is only now being explored with the help of scientists from the Howard Florey Institute.

4 Oct 2007

Big bucks for cooling therapy trial for children with brain injuries

An investment of $11.5 million is being made into a clinical trial to examine a therapy for children with brain injuries.

3 Oct 2007

Cholesterol levels both high and low linked to premature births

A new study suggests that not only is a very low level of cholesterol a danger to pregnant women, but high cholesterol too increases the risk of premature birth.

3 Oct 2007

Low levels of good cholesterol risk for heart disease

According to the latest research reducing the amount of "bad cholesterol" (LDL - low density lipoprotein cholesterol) in the blood is incidental if the proper amount of "good cholesterol" (HDL - high density lipoprotein cholesterol) is not present.

3 Oct 2007

Prostate cancer treatment may encourage spread of cancer cells

According to a new study by researchers in the U.S. the popular prostate cancer treatment, androgen deprivation therapy, may in fact encourage the spread of cancer cells throughout the body.

3 Oct 2007