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Researchers have uncovered a significant contributing factor to interferon resistance of malignant melanoma cells

The finding represents a step forward in understanding the molecular events that govern the growth of this type of cancer and the changes in gene expression and cellular signaling that underlie resistance to established therapies.

26 Sep 2005

Magnetic shoe insoles did not effectively relieve foot pain

...researchers report in the current issue of Mayo Clinic Proceedings. And the results indicate that patients who strongly believed in magnets had pain relief even if they were given false magnets to wear.

26 Sep 2005

New way to create a permanent chemical bond between antibiotics and titanium

Infections associated with inserting a medical device can be devastating, painful, and cause prolonged disability, costing tens of thousands of dollars.

26 Sep 2005

Folate may protect against cognitive decline in older adults

According to a recent report in the American Journal of Clinical Nutrition, folate, a B vitamin found in foods like leafy green vegetables and citrus fruit, may protect against cognitive decline in older adults.

26 Sep 2005

Heart attack patients run an increased risk of developing post-traumatic stress disorder

This may lead to a vicious cycle, with the PTSD associated with heart disease harming the patient's future cardiac heath, according to the study in the current issue of Psychosomatic Medicine.

26 Sep 2005

Aggressive public health efforts to control hypertension may help preserve cognitive abilities as well as cardiovascular health

Not only does high blood pressure adversely affect mental functioning, but the correlation appears to be stronger among African-Americans than among whites, researchers report in the current issue of Psychosomatic Medicine.

26 Sep 2005

Researchers map genetic location that explains why certain blood pressure-lowering drugs aren't effective for some people

"The findings bring us a step closer to developing targeted therapies for patients with high blood pressure who might otherwise be started on medications that won't help," said lead author Sandosh Padmanabhan, Ph.D.

26 Sep 2005

Lead exposures early in life combined with high blood pressure in working age adults may lead to diminishing cognitive abilities in later life

Exposure to lead in early childhood and adolescence may contribute to hypertension-related decline that can impair a person's cognitive abilities, according to a new study presented at the 2005 American Heart Association's High Blood Pressure Research meeting.

26 Sep 2005

Mutations in the gene, called PIG-A may help identify individuals at high risk for cancer

A new study to detect an elevated rate of mutations in a gene on the X chromosome holds promise for developing a test that could identify individuals at risk for developing cancer.

26 Sep 2005

Set of simple "rules" that nature appears to use to design proteins

By examining how proteins have evolved, UT Southwestern Medical Center researchers have discovered a set of simple "rules" that nature appears to use to design proteins, rules the scientists have now employed to create artificial proteins that look and function just like their natural counterparts.

26 Sep 2005

Left handedness may be linked to an increased risk of breast cancer

Researchers in the Netherlands examined the relation between handedness and incidence of breast cancer in over 12,000 healthy, middle aged women born between 1932 and 1941.

26 Sep 2005

Genes from both the mother and father can trigger pre-eclampsia

Pre-eclampsia is a serious condition where abnormally high blood pressure and other disturbances develop in the second half of pregnancy. It occurs in 3-5% of pregnancies and is dangerous for both mother and child.

26 Sep 2005

Scientists reverse memory loss in mice with Alzheimer's

In mice, that had been genetically engineered to develop Alzheimer's disease, scientists were able to reverse the rodents' memory loss by reducing the amount of an enzyme that is crucial for the development of Alzheimer's disease.

26 Sep 2005

Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

Leaky lymphatic vessels are the leading cause of the adult onset obesity observed in a laboratory model developed by investigators at St. Jude Children's Research Hospital.

26 Sep 2005

Scientists eventually may be able to determine the structure of proteins from their genomic sequences

Computers can predict the detailed structure of small proteins nearly as well as experimental methods, at least some of the time, according to new studies by Howard Hughes Medical Institute researchers.

26 Sep 2005

Smoking may increase the risk of developing diabetes

The surprising finding emerged when researchers examined the relationship between smoking and diabetes among participants in a major national study, the Insulin Resistance Atherosclerosis Study (IRAS).

26 Sep 2005

Possible molecular origin of at least nine human diseases of nervous system degeneration

These neurodegenerative diseases, including Huntington's disease, share an abnormal deposit of proteins inside nerve cells. This deposition of protein results from a kind of genetic stutter within the cell's nucleus asking for multiple copies of the amino acid glutamine, a building block of protein structure.

26 Sep 2005

"Designer" rats help show how declining estrogen after menopause can affect hypertension

Scientists at Wake Forest University School of Medicine have created a better research rat – the first to enable them to study how declining estrogen after menopause can affect hypertension, heart failure and kidney damage.

26 Sep 2005

Stopping UK BCG vaccination well justified

From autumn 2005, the long running routine programme to vaccinate school children against tuberculosis with BCG vaccine will stop. This decision brings the UK into line with much of the rest of the world and is well justified, writes Professor Paul Fine in the British Medical Journal (BMJ).

26 Sep 2005

British Medical Journal publishes euthanasia opinions

Next month's debate in the House of Lords could begin the process of changing the law on euthanasia and physician assisted suicide. To help doctors decide where they stand, the British Medical Journal has published a range of opinions.

26 Sep 2005

Medical News

Researchers have uncovered a significant contributing factor to interferon resistance of malignant melanoma cells

Magnetic shoe insoles did not effectively relieve foot pain

New way to create a permanent chemical bond between antibiotics and titanium

Folate may protect against cognitive decline in older adults

Heart attack patients run an increased risk of developing post-traumatic stress disorder

Aggressive public health efforts to control hypertension may help preserve cognitive abilities as well as cardiovascular health

Researchers map genetic location that explains why certain blood pressure-lowering drugs aren't effective for some people

Lead exposures early in life combined with high blood pressure in working age adults may lead to diminishing cognitive abilities in later life

Mutations in the gene, called PIG-A may help identify individuals at high risk for cancer

Set of simple "rules" that nature appears to use to design proteins

Left handedness may be linked to an increased risk of breast cancer

Genes from both the mother and father can trigger pre-eclampsia

Scientists reverse memory loss in mice with Alzheimer's

Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

Scientists eventually may be able to determine the structure of proteins from their genomic sequences

Smoking may increase the risk of developing diabetes

Possible molecular origin of at least nine human diseases of nervous system degeneration

"Designer" rats help show how declining estrogen after menopause can affect hypertension

Stopping UK BCG vaccination well justified

British Medical Journal publishes euthanasia opinions

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