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Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling

Administering a small amount of a potent but potentially toxic anticancer agent along with nanoparticles loaded with a second anticancer agent produced a dramatic inhibition of tumor growth in normally intractable cancers. These findings suggest a new approach to treating malignancies such as pancreatic cancer and diffuse gastric cancer.

5 Mar 2007

Magnetic nanocrystals used to carry tumor-killing drugs

Imagine using a focused magnetic field to concentrate anticancer drugs in and around tumors, and then turning off the magnetic field so that the drugs then leave the body.

5 Mar 2007

Targeted nanoparticles image early tumors

A well-established fact in cancer therapy is that early tumor detection improves the odds that a patient will survive the disease. Now, using nanoparticles targeted to the tiny blood vessels that surround even the smallest tumors, researchers at the Siteman Center for Cancer Nanotechnology Excellence (CCNE) have developed a radioactive imaging agent that was able to identify human tumors in rabbits.

5 Mar 2007

Ultrafine hydrogel nanoparticles: synthetic approach and therapeutic application in living cells

Ultrafine nanoparticles made of a lacy web of polymer and tiny pockets of water may prove to be an ideal vehicle for delivering light-activated drugs to tumors.

5 Mar 2007

Women who smoke during pregnancy can cause permanent vascular damage in their children

The Netherlands Atherosclerosis Risk in Young Adults (ARYA) study showed that participants who were exposed to smoke when their mothers were pregnant resulted in permanent cardiovascular damage that could be detected in young adulthood.

5 Mar 2007

Erectile dysfunction drugs may be better than nitroglycerin in protecting the heart after a severe heart attack

During a heart attack, the heart is deprived of oxygen, which can result in significant damage to heart muscle and tissue. After the attack, most patients require treatment to reduce and repair the damage and improve their chances of survival.

5 Mar 2007

Shyness, genetics and parents

New research from the Child Development Laboratory at the University of Maryland shows that shyness in kids could relate to the manner in which a stress-related gene in children interacts with being raised by stressed-out parents.

5 Mar 2007

Call for decent, sanitary housing for recuperating soldiers at Walter Reed Medical Center

The Disabled American Veterans (DAV) has called upon Defense Secretary Robert Gates to take immediate action to provide decent, sanitary housing for recuperating soldiers at Walter Reed Army Medical Center and to consider moving them to Department of Veterans Affairs facilities closer to their homes.

5 Mar 2007

Study compares Lipitor with Simvastatin

A retrospective analysis of a large U.S. managed care database showed that patients who took Pfizer's cholesterol-lowering medicine Lipitor (atorvastatin calcium) Tablets had a significant 14 percent reduction in the risk of cardiovascular events, including heart attacks and strokes, compared with patients who took simvastatin.

5 Mar 2007

Vaccines for measles-mumps-rubella and varicella are effective in extremely preterm infants

The study, which included 16 term and 16 extremely preterm (born before about 6 months of pregnancy) infants born between May 2002 and May 2005, is the first of its kind to examine the antibody levels of measles, mumps, rubella and varicella in this population before and after vaccination. It was published in this month's Pediatrics.

5 Mar 2007

Preemie lung treatments turn out to be safe

Preemies between 28 and 32 weeks are not harmed by a treatment no longer used to help their lungs mature before birth, according to findings of a study in this month's Pediatrics.

5 Mar 2007

Obesity epidemic fuelling premature puberty in girls

Researchers in the United States say girls who are overweight at the age of three run the risk of reaching puberty as early as nine years old and warn that the obesity crisis is now affecting children's development.

5 Mar 2007

Would be dads advised to stay out of the hot tub

The team led by Dr. Paul J. Turek, a urologist and professor at the University of California, San Francisco, say hot baths can lead to male infertility.

5 Mar 2007

Sleep apnea linked to heart disease

New research in the U.S. suggests that people who suffer from sleep apnea have an increased risk of heart disease.

5 Mar 2007

Severe stress can damage a child's brain

According to researchers in the U.S. children who suffer severe stress may also suffer damage to their brains.

5 Mar 2007

Reduce your heart attack risk by eating whole-grain breakfast cereals

The health benefits of whole-grain breakfast cereals have been lauded yet again by the medical profession.

5 Mar 2007

No decision on Office of Women's Health Funding, FDA Commissioner Von Eschenbach says

FDA Commissioner Andrew von Eschenbach on Wednesday at a House Appropriations subcommittee hearing said he has not made a decision on fiscal year 2007 funding for the agency's Office of Women's Health, Reuters reports.

4 Mar 2007

Actions taken on HPV vaccine proposals in Kentucky, Massachusetts, New Mexico, Ohio, South Dakota and Virginia

Merck's HPV vaccine Gardasil and GlaxoSmithKline's HPV vaccine Cervarix in clinical trials have been shown to be 100% effective in preventing infection with HPV strains 16 and 18, which together cause about 70% of cervical cancer cases.

4 Mar 2007

First Ladies discuss women's heart health

First lady Laura Bush and former first lady Nancy Reagan on Wednesday at the Ronald Reagan Presidential Library near Simi Valley, Calif., participated in a panel discussion on women's cardiac health and toured the "First Ladies Red Dress Collection," a collection of red dresses worn by first ladies that aims to promote heart health among women, the Los Angeles Times reports.

4 Mar 2007

China to punish couples who violate one-child policy

China plans to issue new policies that would bar celebrities and other wealthy people who violate the country's one-child-per-family policy from receiving awards such as "honorary citizen," Yu Xuejun -- director of the department of policy law and regulations for the National Population and Family Planning Commission -- said recently, Xinhua/China Daily reports.

4 Mar 2007

Medical News

Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling

Magnetic nanocrystals used to carry tumor-killing drugs

Targeted nanoparticles image early tumors

Ultrafine hydrogel nanoparticles: synthetic approach and therapeutic application in living cells

Women who smoke during pregnancy can cause permanent vascular damage in their children

Erectile dysfunction drugs may be better than nitroglycerin in protecting the heart after a severe heart attack

Shyness, genetics and parents

Call for decent, sanitary housing for recuperating soldiers at Walter Reed Medical Center

Study compares Lipitor with Simvastatin

Vaccines for measles-mumps-rubella and varicella are effective in extremely preterm infants

Preemie lung treatments turn out to be safe

Obesity epidemic fuelling premature puberty in girls

Would be dads advised to stay out of the hot tub

Sleep apnea linked to heart disease

Severe stress can damage a child's brain

Reduce your heart attack risk by eating whole-grain breakfast cereals

No decision on Office of Women's Health Funding, FDA Commissioner Von Eschenbach says

Actions taken on HPV vaccine proposals in Kentucky, Massachusetts, New Mexico, Ohio, South Dakota and Virginia

First Ladies discuss women's heart health

China to punish couples who violate one-child policy

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