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Neoadjuvant immunotherapy shows promise in multiple cancer types

Treating cancer with immunotherapies known as an immune checkpoint blockade (ICB) prior to surgery (so-called neoadjuvant immunotherapy) has been a rapidly growing area of research, but the scientific community is just scratching the surface of what is possible, according to a review article co-authored by several current and former investigators from the Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Kimmel Cancer Center.

28 Sep 2023

Researchers describe the origin and fate of liver myofibroblasts

Hepatic fibrosis occurs when scar tissue replaces damaged cells in the liver. Over time, accumulating scarring distorts the liver, interferes with its blood supply and may progressively lead to worsening consequences, from cirrhosis to liver failure to liver cancer.

28 Sep 2023

Newly identified stem cell variants drive inflammation in cystic fibrosis patients

Two nationally recognized experts in cloning and stem cell science from the University of Houston, Wa Xian and Frank McKeon, are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis (CF), and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion.

28 Sep 2023

New report calls for government action to tackle insecure work

Accessing stable employment with fair pay and predictable hours is harder for workers in the North and Midlands, which can severely affect their living standards, health, and future job prospects.

28 Sep 2023

Smoking during pregnancy more than doubles risk of premature birth, study finds

Cambridge researchers have found that women who smoke during pregnancy are 2.6 times more likely to give birth prematurely compared to non-smokers – more than double the previous estimate.

28 Sep 2023

Are edible coatings the answer to fresher, eco-friendlier fruit and veg packaging?

Review sheds light on edible coatings as a sustainable alternative to traditional packaging and preservatives in the food industry, particularly for perishable items like fruits and vegetables.

28 Sep 2023

Vaxzevria vaccine boosts mucosal immunity in COVID-19 recovered

Study highlights the ability of the Vaxzevria vaccine in inducing robust mucosal antibody responses, especially in COVID-19-recovered individuals, showcasing a notable defense against various SARS-CoV-2 variants. However, it emphasizes the need for booster doses to enhance anti-SARS-CoV-2 mucosal immunity, especially in infection-naïve individuals, to broaden protection against emerging viral variants.

28 Sep 2023

Grandmother's advice holds true: Scrubbing behind the ears and between the toes may help keep skin healthy

Grandmother was right: Scrubbing behind the ears and between the toes may help keep the skin in those regions healthy, or so says a new study by a team at the George Washington University.

28 Sep 2023

Parental job stress linked to children's socioemotional development

Family mealtimes are important for parents and children as a space to communicate, socialize, and build attachment relationships.

28 Sep 2023

New framework for ethical microbiome research practices that include Indigenous communities

Every person hosts trillions of microorganisms, like bacteria and viruses, on their skin and in organs including those that make up the digestive tract, like their mouth, that collectively make up their microbiome.

28 Sep 2023

Study finds underutilization of weight management interventions in England

Of the more than 1.8 million adults in England with a recorded diagnosis of overweight or obesity, only 3 percent are referred to publicly funded weight management programs, according to a new study publishing September 28th in the open access journal PLOS Medicine by Karen Coulman of University of Bristol, UK, and colleagues.

28 Sep 2023

Double-layer polysaccharide hydrogel overcomes challenges of probiotic delivery

In a groundbreaking study, a research team led by Changhu Xue and Xiangzhao Mao from the Ocean University of China has developed a remarkable double-layer polysaccharide hydrogel (DPH) that promises to revolutionize the field of intestine-targeted oral delivery of probiotics.

28 Sep 2023

Loss of brain interneurons linked to cognitive deficits in aging

Normal aging is usually associated with a decline in memory, although it is unclear what factors play a role.

28 Sep 2023

Swapping meat for Quorn protein could reduce cholesterol and trim waist circumference

People looking to reduce their cholesterol and trim fat from around their waist could try swapping meat for Quorn protein, according to the findings from a new study by Northumbria University, Newcastle, published in the European Journal of Nutrition, which saw positive effects in both areas in just two weeks.

28 Sep 2023

Medical News

Neoadjuvant immunotherapy shows promise in multiple cancer types

Researchers describe the origin and fate of liver myofibroblasts

Newly identified stem cell variants drive inflammation in cystic fibrosis patients

New report calls for government action to tackle insecure work

Smoking during pregnancy more than doubles risk of premature birth, study finds

Are edible coatings the answer to fresher, eco-friendlier fruit and veg packaging?

Vaxzevria vaccine boosts mucosal immunity in COVID-19 recovered

Grandmother's advice holds true: Scrubbing behind the ears and between the toes may help keep skin healthy

Parental job stress linked to children's socioemotional development

New framework for ethical microbiome research practices that include Indigenous communities

Study finds underutilization of weight management interventions in England

Double-layer polysaccharide hydrogel overcomes challenges of probiotic delivery

Loss of brain interneurons linked to cognitive deficits in aging

Swapping meat for Quorn protein could reduce cholesterol and trim waist circumference

Insights and new directions in basic, clinical research into neurodegenerative diseases

Plastic waste in the oceans may spread antibiotic resistance

New approach could improve immune checkpoint inhibitor response in MTAP-deficient tumors

Nicotine e-cigarettes, varenicline, and cytisine most effective for long-term smoking cessation, analysis finds

Weighing the risks and benefits of COVID-19 precautions in 2023

Social isolation linked to higher depression levels during the COVID-19 pandemic

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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