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Unique openings in specific ion channels could lead to development of selective drugs

Ion channels are attractive drug targets due to their importance in health and disease, but finding ways to target a specific ion channel selectively is a major challenge.

31 Aug 2023

New insights into how lung cells detect influenza virus

Researchers from Trinity College Dublin have discovered some new and surprising ways that viral RNA and influenza virus are detected by human lung cells, which has potential implications for treating people affected by such viruses.

31 Aug 2023

Scientists delve deeper into how vaccines work against leishmaniasis

Scientists have established the effectiveness of vaccines they developed to prevent the disfiguring skin disease leishmaniasis in animal studies, and Phase 1 human trial planning is in motion for the most promising candidate.

31 Aug 2023

Boosters slow antibody waning but hit a ceiling: Long-term COVID study reveals limits of immunity

The study tracks the long-term kinetics of antibody responses to SARS-CoV-2 after vaccination and infections in New York healthcare workers from 2020 to 2023. It reveals that antibody waning is slower after booster shots, but there's an upper limit to antibody levels, which gradually lowers with repeated SARS-CoV-2 exposures and vaccinations.

31 Aug 2023

Is the rapid evolution of SARS-CoV-2 in white-tailed deer complicating our fight against the pandemic?

New study reveals rapid evolution of SARS-CoV-2 in Ohio's white-tailed deer population, with a 25% seroprevalence rate. The findings suggest a significant risk of animal-to-human transmission and indicate the virus evolves faster in deer than in humans.

31 Aug 2023

Cracking the code on post-vaccine COVID protection

The study investigates the relationship between antibody levels and behavioral factors in 176 adults vaccinated with Pfizer's BNT162b2, finding that higher levels of specific antibodies correlate with greater protection against symptomatic COVID-19. It also suggests that current commercial assays may need reformatting for better risk prediction.

31 Aug 2023

Socioeconomic distress linked to worse outcomes after heart transplantation

People from socioeconomically distressed communities who underwent heart transplantation between 2004 and 2018 faced a 10% greater relative risk of experiencing graft failure and dying within five years compared to people from non-distressed communities.

31 Aug 2023

Alzheimer's screening just got easier, more accurate with new blood test

A new blood test called p-tau217 shows promise as an Alzheimer's disease biomarker, and when used in a two-step workflow very high accuracy to either identify or exclude brain amyloidosis, the most important and earliest pathology.

31 Aug 2023

Blood NfL levels correlate with severity of Alzheimer's disease pathology

Neuroscience researchers at Wayne State University published a review article that confirms the usefulness of neurofilament light (NfL) blood levels to predict the likelihood and rate of progression of neurodegeneration in Alzheimer's disease.

31 Aug 2023

Coronavirus fusion peptide plays more invasive role in infection than previously thought

Although the COVID-19 pandemic was the first time most of humanity learned of the now infamous disease, the family of coronaviruses was first identified in the mid-1960s.

31 Aug 2023

Study reveals pathogenic mechanism of rare pediatric neurodegenerative disorder

A recent study published in Nature Metabolism has revealed the pathogenic mechanism underlying a rare pediatric neurodegenerative disorder known as mitochondrial enoyl reductase protein-associated neurodegeneration (MEPAN) syndrome.

31 Aug 2023

Dectin-1 stimulation promotes pro-inflammatory response in HIV-positive individuals

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 16, entitled, "Dectin-1 stimulation promotes a distinct inflammatory signature in the setting of HIV-infection and aging."

31 Aug 2023

MU Law Clinic launches program to help homeless veterans

Since 2009, the number of veterans experiencing homelessness across the United States has shrunk by more than 50%, according to a 2022 Department of Housing report.

31 Aug 2023

Universal approach could potentially expand CAR T cell therapy to all blood cancers

A broad new strategy could hold hope for treating virtually all blood cancers with CAR T cell therapy, which is currently approved for five subtypes of blood cancer.

31 Aug 2023

ER-phagy alleviates drug-induced cardiomyopathy in cancer patients

A cell contains many specialized subunits, called organelles, that carry out important tasks such as energy generation, protein synthesis, and calcium outflux. But what happens when something goes wrong with one of the organelles?

31 Aug 2023

Electrical noise stimulation boosts math skills in individuals with lower brain excitability

Exciting a brain region using electrical noise stimulation can help improve mathematical learning in those who struggle with the subject, according to a new study from the Universities of Surrey and Oxford, Loughborough University, and Radboud University in The Netherlands.

31 Aug 2023

Study explores associations between digital media use and psychotic experiences in young adults

On average, young adults in Canada spend several hours on their smartphones every day. Many jump from TikTok to Netflix to Instagram, putting their phone down only to pick up a video game controller.

31 Aug 2023

Exploring the role of the metabolic syndrome in individual mechanisms of liver fibrosis

Chronic liver injury results in the development of liver fibrosis in approximately 25% of individuals in response to diverse insults, and several aspects of the development of liver injury appear to be common to a variety of initiating factors.

31 Aug 2023

MFGM supplement in infant formula linked to long-term cognitive benefits

Breast milk is widely acknowledged as the most beneficial nutrition for infants, but many families face medical or logistical challenges in breastfeeding. In the U.S., just 45% of infants continue to be exclusively breastfed at 3 months of age, according to the Centers for Disease Control.

31 Aug 2023

KFF Health News' 'What The Health?': 3 health policy experts you should know

In this special episode, host Julie Rovner, KFF Health News' chief Washington correspondent, interviews three noted health policy experts.

31 Aug 2023

Medical News

Unique openings in specific ion channels could lead to development of selective drugs

New insights into how lung cells detect influenza virus

Scientists delve deeper into how vaccines work against leishmaniasis

Boosters slow antibody waning but hit a ceiling: Long-term COVID study reveals limits of immunity

Is the rapid evolution of SARS-CoV-2 in white-tailed deer complicating our fight against the pandemic?

Cracking the code on post-vaccine COVID protection

Socioeconomic distress linked to worse outcomes after heart transplantation

Alzheimer's screening just got easier, more accurate with new blood test

Blood NfL levels correlate with severity of Alzheimer's disease pathology

Coronavirus fusion peptide plays more invasive role in infection than previously thought

Study reveals pathogenic mechanism of rare pediatric neurodegenerative disorder

Dectin-1 stimulation promotes pro-inflammatory response in HIV-positive individuals

MU Law Clinic launches program to help homeless veterans

Universal approach could potentially expand CAR T cell therapy to all blood cancers

ER-phagy alleviates drug-induced cardiomyopathy in cancer patients

Electrical noise stimulation boosts math skills in individuals with lower brain excitability

Study explores associations between digital media use and psychotic experiences in young adults

Exploring the role of the metabolic syndrome in individual mechanisms of liver fibrosis

MFGM supplement in infant formula linked to long-term cognitive benefits

KFF Health News' 'What The Health?': 3 health policy experts you should know

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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