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Zinc treatment may help prevent esophageal and oral cancers

Cancer researchers at Jefferson Medical College and the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have found that zinc treatment may help prevent esophageal and oral cancers in those individuals at high risk.

9 Jan 2005

System to help babies avoid brain damage

The same heightened electrical activity that indicates an adult taking a treadmill test isn't getting enough oxygen to his heart is now being measured during labor to see if it can better identify babies in serious distress who need immediate delivery.

9 Jan 2005

Core promoter mutants of Hepatitis B Virus e Antigen associated with development of fulminant hepatitis and liver cancer

Scientists in Brown Medical School, Providence, USA, have found that core promoter mutants of Hepatitis B Virus e Antigen replicate at up to 10-fold higher levels in transfected human hepatoma cells than the wild-type virus.

9 Jan 2005

Pegylated interferon alfa-2b offers the best treatment option for people with chronic hepatitis B infection

Harry Janssen (Erasmus University Medical Centre, Rotterdam, Netherlands) and colleagues assessed whether combination treatment with pegylated interferon alfa-2b and the antiviral agent lamivudine was more efficacious in treating chronic hepatitis B infection than pegylated interferon alfa-2b therapy alone.

7 Jan 2005

Diagnosis of tuberculosis in young children can be confirmed by a straightforward sputum test

Diagnosis of tuberculosis is difficult in infants and young children and can be complicated by HIV infection. Heather Zar (School of Child and Adolescent Health, University of Cape Town, South Africa) and colleagues studied 250 children aged 1 month to 5 years who were admitted for suspected pulmonary tuberculosis in Cape Town. Sputum induction and gastric lavage were done on three consecutive days according to a standard procedure.

7 Jan 2005

Isolating intensive-care patients infected with MRSA does not reduce cross-infection

Results of a UK study published online suggest that the widely practised approach of isolating intensive-care patients infected with MRSA does not reduce cross-infection. Authors of the study caution that this finding should not be extended to general hospital wards, and needs further confirmation from larger studies.

7 Jan 2005

Promising new evidence for the optimal use of biologic therapies for rheumatoid arthritis

A major cause of pain and disability, rheumatoid arthritis (RA) is also potentially the most treatable form of chronic arthritis. Researchers, doctors, and patients agree that a group of drugs called disease-modifying antirheumatic drugs (DMARDs) can effectively reduce joint pain and stiffness.

7 Jan 2005

Strong association between high levels of hyaluronic acid and severe osteoarthritis

A chronic degenerative joint disease, osteoarthritis (OA) is a common cause of pain and disability among older Americans. OA of the knee affects up to 6 percent of the older population, while OA of the hip affects about another 3 percent. While treatments vary, there is hope that early intervention – before joint destruction can be clearly seen and measured on an X-ray image-will improve outcomes.

7 Jan 2005

Fallout from Vioxx and Celebrex market recall challenges industry

The pharmaceutical and biotechnology industries face further marketing and sales challenges in 2005 as the fallout from the Vioxx and Celebrex market recall and warning make it increasingly challenging for companies across the industry to reach physicians and consumers with effective campaigns without the distractions of the unfavorable press these recent events have generated.

7 Jan 2005

FDA clearance to test influenza vaccine, Fluviral

ID Biomedical Corporation announced today that it has received clearance from the U.S. Food and Drug Administration (FDA) to begin immediate clinical testing of its influenza vaccine, Fluviral, in the United States under an Investigational New Drug application (IND).

7 Jan 2005

Potential cure for lymphoma in HIV patients

Stem cell transplants have become the standard of care for patients with relapsed lymphoma, but not for patients who suffer from both this disease and HIV.

7 Jan 2005

Hormone replacement therapy associated with increased risk of stroke

Hormone replacement therapy (HRT) is associated with an increased risk of stroke, especially ischaemic stroke, finds a review of trials published on bmj.com today.

7 Jan 2005

Injuries and deaths caused by unexploded ordnance in Afghanistan

Unexploded military material in Afghanistan cause more injuries and deaths than landmines especially among children, according to research published on bmj.com today.

7 Jan 2005

Financial barriers to a career in medicine are growing

The financial barriers to a career in medicine are growing, the BMA says today (Friday 7 January 2005), as new figures show the average fifth year medical student is in debt by £19,248 - 16% higher than last year - and many owe more than £30,000.

7 Jan 2005

Most alcohol-related plane crashes occur at night and in poor weather

Researchers at Johns Hopkins have found that nighttime flying and worsening weather conditions are two key characteristics of fatal plane crashes in general aviation where alcohol consumption by the pilot was also a factor.

7 Jan 2005

Treatment centres threaten NHS Trusts

Responding to the Secretary of State for Health, John Reid's, report today (7 January 2005) on NHS and Independent Treatment Centres, the Chairman of the BMA's Consultants' Committee, Dr Paul Miller, warned that the centres were destabilising NHS hospitals.

7 Jan 2005

First program to apply RNA interference (RNAi) technology to asthma

Sirna Therapeutics, Inc. has announced the first program to apply RNA interference (RNAi) technology to asthma, a highly prevalent, chronic disease accounting for an estimated $13 billion in healthcare costs in the United States, a number which is forecast to grow considerably by the end of the decade.

7 Jan 2005

New guidelines for treating diabetes

Every year, the American Diabetes Association (ADA) issues Clinical Practice Recommendations, a series of updated recommendations to help health care providers treat people with diabetes using the most current research available.

7 Jan 2005

New form of treatment for cancer of the larynx

Surgeons at Montefiore Medical Center are using a new form of treatment for cancer of the larynx that allows for quicker recovery and shorter hospital stays, and saves the voice box so patients retain the ability to speak.

7 Jan 2005

Peginterferon alfa-2b produced sustained responses in patients with chronic hepatitis B

Results from a large international clinical study reported in this week's issue of The Lancet showed that peginterferon alfa-2b produced sustained responses in patients with chronic hepatitis B. The investigator-initiated study is the largest clinical trial to date with peginterferon alfa-2b therapy for chronic hepatitis B.

7 Jan 2005