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Physical effects of bedrest on older hospital patients can be countered by 25 minutes of walking

As little as 25 minutes a day of slow walking seems to be enough to counter the detrimental physical effects of bedrest on older hospital patients, finds a pooled data analysis of the available evidence, published online in the British Journal of Sports Medicine.

4 Aug 2023

Study discloses vital role of LINC00901 and its regulatory network in pancreatic cancer progression

Chemical modifications of RNA molecules, such as m6A, can critically impact gene expression, influencing various aspects of cancer development and progression.

4 Aug 2023

Artificial sweeteners linked to increased body fat, study finds

Published in the International Journal of Obesity, University of Minnesota Medical School and School of Public Health researchers led a study on the relationship between dietary intake and cardiovascular disease risk factors.

4 Aug 2023

GEMINI test shows promise for early detection of lung cancer

Novel blood testing technology being developed by researchers at the Johns Hopkins Kimmel Cancer Center that combines genome-wide sequencing of single molecules of DNA shed from tumors and machine learning may allow earlier detection of lung and other cancers.

4 Aug 2023

Penn State researchers develop new method for creating cyclopropanes

Chemical structures called cyclopropanes can increase the potency and fine-tune the properties of many drugs, but traditional methods to create this structure only work with certain molecules and require highly reactive - potentially explosive - ingredients. Now, a team of researchers from Penn State has identified and demonstrated a safe, efficient and practical way to create cyclopropanes on a wide variety of molecules using a previously undescribed chemical process.

4 Aug 2023

New study provides promising results for metformin in periodontitis

Periodontitis, a prevalent global health concern, results in the gradual destruction of tooth-supporting tissues and is often exacerbated by oxidative stress conditions and bacterial changes. Current treatment methodologies include mechanical debridement, anti-inflammatory drugs, and regenerative surgery.

4 Aug 2023

Racial disparities in mortality rates persist in the United States

An analysis of 19 causes of death in the United States revealed persistent disparities and a familiar pattern across five racial-ethnic groups and 3,110 counties from 2000 to 2019. That's according to the most comprehensive peer-reviewed research published today in The Lancet.

4 Aug 2023

New technique enables high-resolution analysis of DNA

Function and form are deeply intertwined in biology. Knowing how organisms grow, adapt and reproduce requires understanding their physical structures. Hence the transformative power of the microscope across the past four centuries of science.

4 Aug 2023

New study finds more effective way to coach and inspire

What if there was a more effective way to coach and inspire your employees? Athletes? Students? Even your kids?

4 Aug 2023

Gene expression ratio linked to prognosis in solid tumors

A Ludwig Cancer Research study has identified a pair of genes whose expression by a type of immune cell within tumors is predictive of outcomes for cancer patients and is linked to a vast network of gene expression programs, engaged by multiple cell types in the tumor microenvironment, that control human cancers.

3 Aug 2023

$11 million NIH grant focuses on cognitive function in Down syndrome-associated Alzheimer’s

Neurologist Beau Ances, MD, PhD, talks with his patient, Adam Kloppenberg, who has Down syndrome, at Washington University School of Medicine in St. Louis. People with Down syndrome are at very high risk of developing Alzheimer's disease. Ances is involved in a project led by Jason Hassenstab, PhD, an associate professor of neurology, to develop tools to measure cognitive function in people with Down syndrome-associated Alzheimer's disease.

3 Aug 2023

Researchers discover how aging can lead to chronic metabolic disorders

Korean researchers have unveiled a novel signaling pathway that fosters aging-related chronic metabolic disorders.

3 Aug 2023

Deep learning improves protein design by 10x

The key to understanding proteins - such as those that govern cancer, COVID-19, and other diseases - is quite simple. Identify their chemical structure and find which other proteins can bind to them. But there's a catch.

3 Aug 2023

Radiomic and clinical data could help increase diagnostic accuracy for pediatric Crohn disease

An accepted manuscript published in the American Journal of Roentgenology (AJR) found that deploying a radiomic-based model with T2-weighted MRI data could increase diagnostic accuracy for pediatric Crohn disease (CD).

3 Aug 2023

Fatal coronary heart disease may rise again unless Americans modify three key risk factors

After decades of decline, fatal coronary heart disease may rise again unless Americans modify three major risk factors: smoking, drinking, and obesity.

3 Aug 2023

Peppermint oil may be new option for pain relief after open heart surgery

The use of essential peppermint oil aromatherapy may ease pain severity after open heart surgery and enhance sleep quality as well, suggest the results of a small comparative clinical trial, published online in the journal BMJ Supportive & Palliative Care.

3 Aug 2023

Independent sector to help cut NHS waiting lists

Thirteen new community diagnostic centres (CDCs) - including eight independently run CDCs - are being launched across the country as part of government plans to use the independent sector to cut NHS waiting lists, Health and Social Care Secretary Steve Barclay will announce today.

3 Aug 2023