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Could metformin be a game changer for heart health in non-diabetics?

Using Mendelian randomization, researchers found that altering seven metformin targets led to improved blood pressure and BMI in non-diabetic individuals. The study suggests the potential for metformin's role in reducing cardiovascular risks in the general population, although more research is needed.

24 Sep 2023

Has the COVID-19 pandemic widened the mental health gap in the UK?

The study explores the varying mental health impacts of the COVID-19 pandemic on the UK's adult population, revealing increased inequalities and distress. Utilizing both surveys and focus group discussions, the research emphasizes the urgent need for targeted interventions and policy responses to address deteriorating mental health and growing disparities.

24 Sep 2023

Genetic link between migraines and breast cancer risk uncovered

Using Mendelian randomization analysis, the study finds a genetic link between migraine susceptibility and increased risk of overall and estrogen receptor-positive breast cancer. However, the findings suggest caution in interpretation, highlighting the need for further research to solidify these associations.

24 Sep 2023

Comparing two plasma p-tau217 assays for Alzheimer's detection and monitoring

Researchers compared two commercially available blood tests based on the biomarker p-tau217 for diagnosing Alzheimer's disease in 294 patients. Both tests demonstrated robust diagnostic capabilities, strongly correlating with established Alzheimer's biomarkers from PET scans.

24 Sep 2023

Social adversity and stress leave distinct signatures on mom and baby gut health

Researchers evaluate the effect of social disadvantages and psychological stressors on the gut microbiome of mothers and their infants.

24 Sep 2023

Plant-based proteins boost muscle mass and cut fat in older adults

Plant-based proteins are just as effective as animal-based options in maintaining muscle mass and strength in older adults, a new meta-analysis finds. The study shows that plant proteins can even aid in reducing fat mass, offering a sustainable and healthful option for combating age-related muscle decline.

24 Sep 2023

Everyday chemicals linked to increased cancer risk, especially in women

This study identifies links between exposure to chemicals like PFAS, parabens, and phenols and increased cancer risk, particularly among women and across racial groups. The findings spotlight the role of environmental toxins in hormone-related cancers, suggesting new avenues for cancer prevention and mitigation strategies.

24 Sep 2023

Exercise boosts immune defense in Lynch syndrome patients

Aerobic exercise, specifically cycling, shows promise in reducing inflammation and boosting immune responses in the colonic tissue of Lynch syndrome patients, a group at high risk for colorectal cancer. The study suggests that regular exercise may offer a preventive approach for this patient population, though further randomized trials are needed.

24 Sep 2023

Study reveals non-coding genetic variants associated with Alzheimer’s disease functioning in microglia

Scientists studying Alzheimer's disease (AD) have identified thousands of genetic variants in the genome in the development of this progressive neurodegenerative disease.

23 Sep 2023

Certain gut microbes may be linked to skeletal health

There is growing evidence that a relative abundance of certain gut microbes may be related to skeletal health, according to a new study published in Frontiers in Endocrinology.

22 Sep 2023

Photobiomodulation in sleep has more therapeutic effects for Alzheimer's disease than in wakefulness

It is well known that sleep is the best medication. However, it is still unknown why the brain recovers better in sleep and whether these processes can be controlled.

22 Sep 2023

TB cases in England increase by 7% in the first half of 2023

Data from the UK Health Security Agency (UKHSA) indicates that cases of TB in England increased by 7% in the first half of 2023 compared to the same timeframe in 2022, with 2,408 notifications compared to 2,251 in the first 2 quarters of 2022.

22 Sep 2023

NYU Langone Health named No. 1 in the nation for quality and patient safety

NYU Langone Health has once again been named No. 1 in the nation for quality and patient safety by Vizient Inc., a leading healthcare performance improvement organization that determines its rankings based on mortality and infection rates, patient experience scores, and other critical quality measures.

22 Sep 2023

Rare genetic variants involved in male-pattern hair loss identified

A receding hairline, a total loss of hair from the crown, and ultimately, the classical horseshoe-shaped pattern of baldness: Previous research into male pattern hair loss, also termed androgenetic alopecia, has implicated multiple common genetic variants.

22 Sep 2023

Using recombinase polymerase amplification for rapid and visual detection of monkey B virus

Announcing a new article publication for Zoonoses journal. Monkey B virus (BV) infection in humans and other macaque species has a mortality rate of approximately 80%.

22 Sep 2023

Mechanoresilient cancer cells more prone to metastasis

The ability of cancer cells to metastasize, or spread from one part of the body to another, is one of the reasons why cancer can be extremely challenging to treat.

22 Sep 2023

Researchers identify key regulators involved in genesis of multiple sclerosis lesions

By means of CRISPR screening, LMU researchers have provided the first ever comprehensive molecular characterization of T cell infiltration into the central nervous system of people with MS.

22 Sep 2023

Machine learning speeds up virtual drug screening by 10-fold

Boosting virtual screening with machine learning allowed for a 10-fold time reduction in the processing of 1.56 billion drug-like molecules. Researchers from the University of Eastern Finland teamed up with industry and supercomputers to carry out one of the world's largest virtual drug screens.

22 Sep 2023

Cellular crosstalk between mother and offspring is more complex than expected

Scientists have known for decades that pregnancy requires a mother's body to adjust so that her immune system does not attack the growing fetus as if it were a hostile foreign invader.

22 Sep 2023

Researchers receive $1.2 million from NIH to expand and refine the robotic eye examination

A collaboration between researchers at the University of Illinois Urbana-Champaign and Duke University has developed a robotic eye examination system, and the National Institutes of Health has awarded the researchers $1.2 million to expand and refine the system.

22 Sep 2023