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Mutations in AGC kinase motif linked to colorectal cancer growth

Cancer spreads throughout the human body in cunning, almost militaristic, ways. For example, it can manipulate our genetic make-up, take over specific cell-to-cell signaling processes, and mutate key enzymes to promote tumor growth, resist therapies, and hasten its spread from the original site to the bloodstream or other organs.

3 Jul 2023

New oral films could revolutionize drug delivery for patients

Conventional ways of administering medication - by swallowing tablets, consuming bitter syrups, injections or rectal insertions - could be distressing and unpleasant for some patients, especially young children or the elderly.

3 Jul 2023

Dementia patients can still learn new things, study shows

People with dementia still have the ability to learn new things despite their illness. This is the conclusion of a doctoral thesis recently presented at Linköping University, Sweden.

3 Jul 2023

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

Activation of the NRF2 transcription factor shows promise as a potential treatment approach for non-alcoholic fatty liver disease (NAFLD), a condition associated with oxidative stress and liver damage. By screening FDA-approved drugs, researchers identified six compounds that enhanced NRF2 activity and demonstrated protective effects against oxidative stress and lipid accumulation.

3 Jul 2023

Education and community exposure can increase breastfeeding rates in rural areas, study finds

While formula-feeding babies is a safe and convenient option, research studies have shown natural breastfeeding is linked to numerous health benefits for both mother and child.

3 Jul 2023

SIRT1: Unlocking the secrets to better vascular health through resveratrol and energy restriction

Research investigates the effects of SIRT1 activation through resveratrol supplementation and energy restriction on vascular function in adults. The study reveals that both interventions increase circulating SIRT1, reduce sympathetic activity, and have positive impacts on vascular reactivity, indicating potential benefits for vascular health.

3 Jul 2023

Study links menopausal hormone therapy to increased risk of dementia and Alzheimer's

Research investigates the impact of menopausal hormone therapy on the risk of developing dementia, considering different types of hormone treatment, duration of use, and age at usage. The study aims to assess the association between hormone therapy and dementia development.

3 Jul 2023

Resistance training could be a simple and affordable therapy for Alzheimer's patients

Regular physical exercise, such as resistance training, can prevent Alzheimer's disease, or at least delay the appearance of symptoms, and serves as a simple and affordable therapy for Alzheimer's patients.

3 Jul 2023

Ancient retrovirus may be responsible for aggressive brain cancers

The median length of survival after diagnosis of glioblastoma is 14 months, but some of these brain tumors are more aggressive and resistant to treatment than others, and a new study from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine suggests reactivation of an ancient retrovirus may be at least partly to blame.

3 Jul 2023

New study uncovers effects of beer compound on cartilage cells in osteoarthritis

Formononetin (FNT), an isoflavonoid present in beer, was investigated for its effects on chondrocytes, the cells responsible for joint health. While low levels of FNT showed no harm and reduced inflammation, excessive exposure promoted catabolic responses, shedding light on the relationship between beer consumption and osteoarthritis risk.

3 Jul 2023

Study sheds light on the wide disparities within maternal mortality rates in the U.S.

A new study by investigators from the Institute for Health Metrics and Evaluation at the University of Washington and Mass General Brigham found that maternal mortality rates have worsened from 1999 to 2019, hitting some racial and ethnic groups and states harder than others.

3 Jul 2023

Stalled progress: Enteric infection reduction efforts slowed in 2022 despite pandemic easing

The research paper focuses on the lack of progress in reducing enteric infection incidence in 2022 despite the subsiding influence of the COVID-19 pandemic. It emphasizes the need for collaborative efforts among food stakeholders and regulators to mitigate pathogen contamination during poultry slaughter and prevent contamination of leafy greens.

3 Jul 2023

Wastewater surveillance highlights significant underestimation of COVID-19 cases in Canada

Research examines the correlation between SARS-CoV-2 levels in untreated water and COVID-19 cases and hospitalizations in Ontario, Canada. It also highlights the value of wastewater data in enhancing local decision-making and COVID-19 surveillance systems.

3 Jul 2023

Medical News

Mutations in AGC kinase motif linked to colorectal cancer growth

New oral films could revolutionize drug delivery for patients

Dementia patients can still learn new things, study shows

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

Education and community exposure can increase breastfeeding rates in rural areas, study finds

SIRT1: Unlocking the secrets to better vascular health through resveratrol and energy restriction

Study links menopausal hormone therapy to increased risk of dementia and Alzheimer's

Resistance training could be a simple and affordable therapy for Alzheimer's patients

Ancient retrovirus may be responsible for aggressive brain cancers

New study uncovers effects of beer compound on cartilage cells in osteoarthritis

Study sheds light on the wide disparities within maternal mortality rates in the U.S.

Stalled progress: Enteric infection reduction efforts slowed in 2022 despite pandemic easing

Wastewater surveillance highlights significant underestimation of COVID-19 cases in Canada

Does COVID-19 increase the risk of bacterial infections in infants?

AI predicts on- and off-target activity of RNA-targeting CRISPRs

Lesion network mapping identifies new brain circuit linked to epilepsy

Study calls for renaming of 'obesity' to better reflect the disease

Korean researchers develop hydrogel that could revolutionize treatment for female infertility

Cell therapy using genome-edited iPS cells could be a new treatment for Fabry disease

Base editing shows promise for treating sickle cell disease and beta thalassemia

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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