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Reviving a forgotten antibiotic: Old drug shows new promise against superbugs

Research discusses the activity spectrum of nourseothricin and its components, S-F and S-D, against drug-resistant, gram-negative pathogens. S-F showed promising activity against NDM-1-expressing Klebsiella pneumoniae Nevada strain with minimal toxicity, and it probes the A-decoding site potentially accounting for its miscoding activity.

17 May 2023

Oral cancer game-changer: Researchers develop 'normalized nerve density' metric for tumor assessment

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17 May 2023

Tick-Tock on the biological clock: Shift work patterns may disrupt female fertility

Only four weeks of shift work-like patterns in female mice are enough to disrupt their biological clock and reduce fertility, according to research presented at the 25th European Congress of...

16 May 2023

Study finds uncertainty and misperceptions about sources of nicotine in e-cigarettes among youth

Using e-cigarettes, or vaping, is highly popular among youth, with more than 2 million high school students using the products, according to the FDA.

16 May 2023

Study unveils ATP as a key player in ovulation, paves the way for novel infertility treatments

Research explores the role of ATP as a potential neurotransmitter in stimulating kisspeptin neurons to induce ovulation in rodents. The findings shed light on the neurobiological mechanisms involved in ovulation and may have implications for understanding and treating ovulation disorders.

16 May 2023

New liquid biopsy tool shows 30% increased sensitivity in detecting ctDNA

Pancreatic cancer is the seventh leading cause of cancer death worldwide and despite the increasing incidence of this disease, effective treatments are lacking and prognosis for patients with this tumor type remains poor, with approximately 70% of patients dying within one year of diagnosis.

16 May 2023

Caffeine connection: Pre-teen caffeine consumption linked to early nicotine use

Research explores the relationship between caffeine use and nicotine onset among early adolescents, shedding light on a potential contributing factor to youth nicotine initiation. It emphasizes the importance of understanding the influence of caffeine in preventing early nicotine use.

16 May 2023

Study establishes a mechanistic link between obesity and oral cancer immune escape

A team from the University of Michigan Rogel Cancer Center and School of Dentistry, led by Yu Leo Lei, D.D.S., Ph.D., have identified a mechanism in mice for how obesity affects some oral cancers' ability to escape from the immune system.

16 May 2023

New technique could mechanically enhance glymphatic transport in the mouse brain

Like the lymphatic system in the body, the glymphatic system in the brain clears metabolic waste and distributes nutrients and other important compounds.

16 May 2023

Researchers may have identified a molecular cause for memory changes in early childhood

How do our brains become capable of creating specific memories? In one of the first preclinical studies to examine memory development in youth, a research team at The Hospital for Sick Children (SickKids) may have identified a molecular cause for memory changes in early childhood.

16 May 2023

Long-ignored antibiotic could help fight against multi-drug resistant bacteria

"The end of modern medicine as we know it." That's how the then-director general of the World Health Organization characterized the creeping problem of antimicrobial resistance in 2012.

16 May 2023

Grape expectations: Dietary grapes promote subtle shifts in human microbiome with potential health implications

Research investigates the potential health benefits of grape consumption by examining its impact on the human microbiome. By analyzing microbiome composition and metabolites, the study provides insights into the relationship between grapes and human health.

16 May 2023

Long-COVID's crippling aftermath: Study reveals persistent symptoms severely impact quality of life, especially in women

Research examines the impact of long-Covid syndrome on the health-related quality of life (HRQoL) of patients with mild or moderate SARS-CoV-2 infections. It reveals significant impairments in physical and mental health, emphasizing the need for long-term surveillance and support for affected individuals.

16 May 2023

COMBINEDBrain receives grant from the Chan Zuckerberg Initiative to accelerate research for rare neurological disorders

COMBINEDBrain's Founder and Director, Dr. Terry Jo Bichell, understands the power of collaboration. In her years as a neuroscientist, advocate, and rare patient parent, she has witnessed the field of neurodevelopment transform from a broad focus on autism or intellectual disability, to an era based on rare genetic disorders.

16 May 2023

"Smart" sutures can detect inflammation and release drugs

Inspired by sutures developed thousands of years ago, MIT engineers have designed "smart" sutures that can not only hold tissue in place, but also detect inflammation and release drugs.

16 May 2023

Machine learning reveals sex-specific Alzheimer's risk genes

Research explores sex-specific gene associations in Alzheimer's disease using a machine-learning approach. It reveals immune response pathways in both sexes and stress-response pathways in males, highlighting potential biomarkers and therapeutic targets for personalized treatments.

16 May 2023

Nemours Children's Health selected to conduct first gene therapy clinical trial for Morquio A syndrome

As part of the Foundation for the National Institutes of Health Accelerating Medicines Partnership Bespoke Gene Therapy Consortium, Nemours Children's Health has been chosen to conduct a first-of-its-kind gene therapy clinical trial for Morquio A syndrome.

16 May 2023

Liquid chemical exposure associated with increased risk of Parkinson's disease

Two years of heavy exposure to TCE, a liquid chemical that lingers in the air, water and soil, may increase the risk of Parkinson's disease by 70%.

16 May 2023

Mast cells play a crucial role in the development of chronic myeloid leukemia

Chronic myeloid leukemia (CML) is a type of blood cancer that arises from malignant changes in blood-forming cells of the bone marrow.

16 May 2023

Reduction in neighborhood-related stress leads to improvement in kids' asthma symptoms

Children whose families participated in a program that helped them move from distressed neighborhoods to areas with lower rates of poverty and better public resources like schools and parks experienced significant improvements in severe asthma episodes, according to a new study led by a researcher at Dell Medical School at The University of Texas at Austin.

16 May 2023

Medical News

Reviving a forgotten antibiotic: Old drug shows new promise against superbugs

Oral cancer game-changer: Researchers develop 'normalized nerve density' metric for tumor assessment

Tick-Tock on the biological clock: Shift work patterns may disrupt female fertility

Study finds uncertainty and misperceptions about sources of nicotine in e-cigarettes among youth

Study unveils ATP as a key player in ovulation, paves the way for novel infertility treatments

New liquid biopsy tool shows 30% increased sensitivity in detecting ctDNA

Caffeine connection: Pre-teen caffeine consumption linked to early nicotine use

Study establishes a mechanistic link between obesity and oral cancer immune escape

New technique could mechanically enhance glymphatic transport in the mouse brain

Researchers may have identified a molecular cause for memory changes in early childhood

Long-ignored antibiotic could help fight against multi-drug resistant bacteria

Grape expectations: Dietary grapes promote subtle shifts in human microbiome with potential health implications

Long-COVID's crippling aftermath: Study reveals persistent symptoms severely impact quality of life, especially in women

COMBINEDBrain receives grant from the Chan Zuckerberg Initiative to accelerate research for rare neurological disorders

"Smart" sutures can detect inflammation and release drugs

Machine learning reveals sex-specific Alzheimer's risk genes

Nemours Children's Health selected to conduct first gene therapy clinical trial for Morquio A syndrome

Liquid chemical exposure associated with increased risk of Parkinson's disease

Mast cells play a crucial role in the development of chronic myeloid leukemia

Reduction in neighborhood-related stress leads to improvement in kids' asthma symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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