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Developers of gene therapies can utilize FDA guidance to prepare ODD or RPDD applications

Providing an overview of the submissions process and examples of U.S. Food and Drug Administration (FDA) applications for Orphan Drug Designation (ODD) and Rare Pediatric Disease Designation (RPDD), a new article can help developers of gene therapies for rare genetic diseases.

27 Mar 2023

UQ researchers lead new study on bacteria that cause sepsis

University of Queensland researchers have led a national study on the four main bacteria that cause sepsis, providing new targets for developing antibiotics.

27 Mar 2023

More positive relationship experiences lead to better physiological functioning in daily life

Social relationships influence physical health, but questions remain about the nature of this connection. New research in Social Psychological and Personality Science suggests that the way you feel about your close relationships may be affecting the way your body functions.

27 Mar 2023

IU Cancer Center secures new, renewed ACS funding to support research and education programs

As part of a longstanding partnership, the Indiana University Melvin and Bren Simon Comprehensive Cancer Center has received new and renewed funding from the American Cancer Society to support research and education programs.

27 Mar 2023

Molecules in breast milk not only feed the baby but also feed the infant's gut microbiome

A University of Massachusetts Amherst nutrition scientist who has spent his career studying breast milk has demonstrated how beneficial microbes in the gut of infants use nitrogen from human milk to support pediatric nutrition and development.

27 Mar 2023

Combination of hydrocortisone and fludrocortisone benefits patients with septic shock

Sepsis occurs in approximately 1.7 million hospitalizations in the U.S. with in more than a third of hospitalizations resulting in death.

27 Mar 2023

American Diabetes Alert Day: A one-day "wake-up call" to the danger of diabetes

March 28 is Diabetes Alert Day, a one-day "wake-up call" to the danger of diabetes and the importance of understanding your risk.

27 Mar 2023

Myeloid cells can harbor HIV in people taking antiretroviral therapy

A subset of white blood cells, known as myeloid cells, can harbor HIV in people who have been virally suppressed for years on antiretroviral therapy, according to findings from a small study supported by the National Institutes of Health.

27 Mar 2023

Computational approach used to understand the mechanisms of protein folding in tauopathies

A team at UT Southwestern has developed a computational approach to uncover mechanisms of protein misfolding linked to neurodegenerative diseases.

27 Mar 2023

Researchers discover a new role for one of the genes linked to hereditary spastic paraplegia

Researchers from the University of Seville and the Seville Institute of Biomedicine (IBiS), in collaboration with the University of Cambridge, have identified a new role for one of the genes related to hereditary spastic paraplegia.

27 Mar 2023

Mount Sinai launches initiative to increase representation of Black men at the upper levels of management

The Mount Sinai Health System has announced the Growth in Operations, Administrations, and Leadership Society (GOALS), an initiative to increase the representation of Black men at the middle and upper levels of management by creating pathways for career advancement through networking, mentorship, and advancement opportunities.

27 Mar 2023

Breast tumors of women from different racial groups have diverse cellular, microbial and genomic features

The breast tumors of Asian, Black and white women have very different cellular, microbial and genomic features that could potentially be used to personalize care or predict disease progression, according to new research by investigators at the Johns Hopkins Kimmel Cancer Center.

27 Mar 2023

Targeting the STING pathway with a combination strategy promotes antitumor activity

Immunotherapies have greatly improved the outcomes of many patients with melanoma. But there is still a need for new approaches for the subset of patients who do not respond well to this type of therapy.

27 Mar 2023

Updated expert consensus statement on transcatheter left atrial appendage closure released

Today, the Society for Cardiovascular Angiography & Interventions and the Heart Rhythm Society released an updated expert consensus statement on transcatheter left atrial appendage closure (LAAC).

27 Mar 2023

New statement suggests next steps to interpret incidentally identified gene variants related to heart disease

Increasing use of genetic testing means people may discover they have a gene variant associated with some types of cardiovascular disease (CVD).

27 Mar 2023

Delay in early development of the embryo associated with likelihood of miscarriage

Embryos in pregnancies that end in miscarriage take longer to develop in the womb than those in pregnancies that result in live births, according to new research published today (Monday) in Human Reproduction, one of the world's leading reproductive medicine journals.

27 Mar 2023

New ways to increase work participation and quality of life among individuals with disabilities

The unemployment rate for persons with disabilities in the United States, particularly youth, is more than double the rate of those without a disability.

27 Mar 2023

Elite judo athletes grapple with getting a good night's sleep, study shows

Poor sleep quality reduces physical recovery and performance. For high-level athletes, a lack of good-quality sleep can be especially damaging for their bodies and performance results.

27 Mar 2023

New study aims to help physically disabled people gain better access to cervical screening

A team of researchers led by Keele University - comprising psychologists, GPs, and nurses - are leading a new study funded by the National Institute for Health and Care Research to help physically disabled women and people with a cervix gain better access to cervical screening, in a bid to reduce cervical cancer.

27 Mar 2023

Demographic, geographic, and temporal variables associated with C. auris cases in Italy

A recent study reported growing cases of Candida auris in North Italy.

27 Mar 2023

Medical News

Developers of gene therapies can utilize FDA guidance to prepare ODD or RPDD applications

UQ researchers lead new study on bacteria that cause sepsis

More positive relationship experiences lead to better physiological functioning in daily life

IU Cancer Center secures new, renewed ACS funding to support research and education programs

Molecules in breast milk not only feed the baby but also feed the infant's gut microbiome

Combination of hydrocortisone and fludrocortisone benefits patients with septic shock

American Diabetes Alert Day: A one-day "wake-up call" to the danger of diabetes

Myeloid cells can harbor HIV in people taking antiretroviral therapy

Computational approach used to understand the mechanisms of protein folding in tauopathies

Researchers discover a new role for one of the genes linked to hereditary spastic paraplegia

Mount Sinai launches initiative to increase representation of Black men at the upper levels of management

Breast tumors of women from different racial groups have diverse cellular, microbial and genomic features

Targeting the STING pathway with a combination strategy promotes antitumor activity

Updated expert consensus statement on transcatheter left atrial appendage closure released

New statement suggests next steps to interpret incidentally identified gene variants related to heart disease

Delay in early development of the embryo associated with likelihood of miscarriage

New ways to increase work participation and quality of life among individuals with disabilities

Elite judo athletes grapple with getting a good night's sleep, study shows

New study aims to help physically disabled people gain better access to cervical screening

Demographic, geographic, and temporal variables associated with C. auris cases in Italy

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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