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$Forxiga (dapagliflozin) approved in Great Britain for symptomatic chronic heat failure across the full spectrum of left ventricular ejection fraction$

Forxiga (dapagliflozin) approved in Great Britain for symptomatic chronic heat failure across the full spectrum of left ventricular ejection fraction

AstraZeneca today announced that the Medicines and Healthcare products Regulatory Agency (MHRA) has granted a licence extension for dapagliflozin in Great Britain for the treatment of symptomatic chronic heart failure (HF) in patients with HF and a left ventricular ejection fraction (LVEF) >40%, including HF with mildly reduced ejection fraction (HFmrEF) and preserved ejection fraction (HFpEF).

From AstraZeneca 12 Dec 2022

The benefit-risk of the mRNA-1273 COVID-19 vaccine

Researchers modeled the benefit-risk of Moderna’s COVID-19 mRNA-1273 vaccine.

12 Dec 2022

Knowledge and attitudes to mpox among GBMSM in Australia

Researchers presented the results of a cross-sectional survey done in Australia between August and September 2022.

12 Dec 2022

In rural America, deadly costs of opioids outweigh the dollars tagged to address them

Tim Buck knows by heart how many people died from drug overdoses in his North Carolina county last year: 10. The year before it was 12 — an all-time high.

12 Dec 2022

KHN investigation: The system feds rely on to stop repeat health fraud is broken

The federal system meant to stop health care business owners and executives from repeatedly bilking government health programs fails to do so, a KHN investigation has found.

12 Dec 2022

Aging influences the diagnosis and treatment of heart attacks in patients over age 75

For people ages 75 and older, age-related changes in general health and in the heart and blood vessels require consideration and likely modifications in how heart attacks and heart disease are treated, according to a new American Heart Association scientific statement published today in the Association's flagship, peer-reviewed journal Circulation.

12 Dec 2022

Study shows emerging Omicron sublineages efficiently evade neutralization independent of immunization history

Researchers evaluated the effects of hybrid immunity and booster vaccination on Omicron sublineages.

12 Dec 2022

Multiscale landscaping of droplet wettability and mobility of N95 masks

Researchers characterized the wettability of fibrous layers of N95 respirators or face masks using contact angle goniometers.

12 Dec 2022

What is the incidence of viral rebound after treatment with nirmatrelvir-ritonavir and molnupiravir?

Researchers evaluated the incidence of COVID-19 rebound among SARS-CoV-2 -positive patients treated with oral antiviral drugs such as nirmatrelvir-ritonavir combination and molnupiravir.

12 Dec 2022

Ongoing Phase I clinical trial demonstrates successful re-treatment with CAR T cell therapy

Researchers from the University of Pennsylvania's Abramson Cancer Center presented preliminary results of an ongoing Phase I clinical trial demonstrating successful re-treatment with CAR T cell therapy for patients whose cancers relapsed after previous CAR T therapy at the 2022 American Society of Hematology Annual Meeting.

12 Dec 2022

Off-the-shelf immunotherapy could offer new hope for patients with hard-to-treat multiple myeloma

A new therapy that makes the immune system kill bone marrow cancer cells was successful in as many as 73 percent of patients in two clinical trials, according to researchers from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai.

12 Dec 2022

Study shows potential benefits of efgartigimod as a treatment for immune thrombocytopenia

Patients taking efgartigimod, a drug being studied for use to treat chronic primary immune thrombocytopenia (ITP), exhibited a significantly greater improvement in platelet counts which are essential to clotting and stopping bleeding, compared to those taking a placebo, according to results reported from the ADVANCE IV clinical trial, which was conducted globally, including at Georgetown University Medical Center.

12 Dec 2022

ASCOT trial pinpoints most efficient level of blood thinning treatment for hospitalized COVID-19 patients

The COVID-19 global pandemic remains a major public health challenge. ASCOT researchers aim to discover which treatments are most effective in patients hospitalized with COVID-19.

12 Dec 2022

A-HIPI decision model can predict survival in adults with advanced-stage Hodgkin lymphoma

Investigators from Rutgers Cancer Institute of New Jersey, the state's only NCI-designated Comprehensive Cancer Center and leading cancer program along with Tufts Medical Center in Boston, developed and validated the Advanced-stage Hodgkin lymphoma International Prognostication Index (A-HIPI).

12 Dec 2022

Medical News

Forxiga (dapagliflozin) approved in Great Britain for symptomatic chronic heat failure across the full spectrum of left ventricular ejection fraction

The benefit-risk of the mRNA-1273 COVID-19 vaccine

Knowledge and attitudes to mpox among GBMSM in Australia

In rural America, deadly costs of opioids outweigh the dollars tagged to address them

KHN investigation: The system feds rely on to stop repeat health fraud is broken

Aging influences the diagnosis and treatment of heart attacks in patients over age 75

Study shows emerging Omicron sublineages efficiently evade neutralization independent of immunization history

Multiscale landscaping of droplet wettability and mobility of N95 masks

What is the incidence of viral rebound after treatment with nirmatrelvir-ritonavir and molnupiravir?

Ongoing Phase I clinical trial demonstrates successful re-treatment with CAR T cell therapy

Off-the-shelf immunotherapy could offer new hope for patients with hard-to-treat multiple myeloma

Study shows potential benefits of efgartigimod as a treatment for immune thrombocytopenia

ASCOT trial pinpoints most efficient level of blood thinning treatment for hospitalized COVID-19 patients

A-HIPI decision model can predict survival in adults with advanced-stage Hodgkin lymphoma

How the COVID-19 pandemic impacted the treatment pancreatic cancer patients

Reports of Mpox disease following recent vaccination

Severe COVID-19 causes aging-like changes in the human brain

Intranasal recombinant MVA-based vaccines effective against SARS-CoV-2 variants in mice

How convergent evolution is creating new COVID-19 waves

Study of 1.1 million children finds no association between SARS-CoV-2 infection and type 1 diabetes risk

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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