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Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Small interfering RNAs, or siRNAs, hold promise to treat tumors, through their ability to specifically knock down oncogenes that promote tumor growth, without the toxicity that accompanies chemotherapy. However, the siRNAs need a delivery vehicle to protect them from degradation and clearance on their journey through the bloodstream to the cancer tumor.

25 May 2022

Largest study to date on long COVID identifies a broad list of diagnoses

Researchers characterize post-acute sequelae of SARS-CoV-2 infection.

25 May 2022

Living in areas with high social vulnerability associated with worse outcomes after traumatic injury

Traumatic injuries - such as physical injuries resulting from a car accident, fall, gunshot or stabbing - are one of the most common causes of impairment and disability worldwide.

24 May 2022

Anosmia in pediatric COVID-19

The current paper, published in The Pediatric Infectious Disease Journal, examines the prevalence of anosmia in children with COVID-19 using a smell awareness survey.

24 May 2022

Son preference may impact Nepali girls’ health and well-being in complex, nuanced ways

The desire for a son could mean Nepali mothers stop breastfeeding infant daughters sooner, says new research.

24 May 2022

New study counters claims that COVID-19 vaccines reduce fertility and affect fetal growth

New experiments conducted in mice add to mounting evidence in opposition to a popular claim that COVID-19 vaccination during early pregnancy may cause birth defects or fetal growth problems.

24 May 2022

Anti-SARS-CoV-2 antibodies from breast milk persist in infants’ digestive tract

The current preliminary investigation study published in the journal Nutrients sought to investigate the longevity of anti-SARS-CoV-2 immunoglobulin (Ig)A and IgG in breast milk during the in vitro-simulated gastrointestinal digestion.

24 May 2022

Study estimates $1.8 billion in Medicare spending on drugs with accelerated approval

The U.S. federal government spent an estimated $1.8 billion in Medicare funds in 2019 on drugs whose clinical benefits have yet to be confirmed by the Food and Drug Administration, a new study led by researchers from the Johns Hopkins Bloomberg School of Public Health suggests.

24 May 2022

Hydration restores airway integrity in people with cystic fibrosis

Cystic fibrosis is a rare genetic disease which can cause very serious symptoms. In particular, patients suffer from chronic bacterial infections that can lead to respiratory failure.

24 May 2022

Engineered water nanostructures as a new technology against SARS-CoV-2

In a recent study published in the MDPI journal Nanomaterials, a research group from the United States (US) has shown the possibility of inactivating surrogates of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on surfaces with the use of specific water nanostructures incorporated with nature-derived antimicrobials.

24 May 2022

Changes in dopamine levels in the brain affect emotion-recognition

Emotion-recognition among people with disorders such as Parkinson's disease or schizophrenia may be affected by changes in the levels of dopamine in the brain, say researchers at the University of Birmingham.

24 May 2022

Study reports on the first instances of in-hospital, household transmission of monkeypox

A new retrospective study of seven patients diagnosed with monkeypox in the UK between 2018 and 2021, suggests that some antiviral medications might have the potential to shorten symptoms and reduce the amount of time a patient is contagious.

24 May 2022

Factors affecting exercise during COVID-19 pandemic

Researchers identify the barriers and facilitators to PA during the COVID-19 pandemic across different demographic groups.

24 May 2022

Detailed analysis shows women who have twins are not more fertile

Are women who have twins more fertile? While previous studies concluded they are, a detailed analysis of more than 100,000 births from pre-industrial Europe by an international team of scientists shows they are not.

24 May 2022

COVID-19 vaccine effectiveness wanes more quickly in cancer patients, study finds

A study co-led by the Universities of Oxford, Birmingham and Southampton and the UK Health Security Agency (UKHSA), published in Lancet Oncology today by the UK Coronavirus Cancer Evaluation Project, has found that while COVID-19 vaccination is effective in most cancer patients, the level of protection against COVID-19 infection, hospitalisation and death offered by the vaccine is less than in the general population and vaccine effectiveness wanes more quickly.

24 May 2022

Insilico Medicine nominates novel preclinical candidate targeting 3CL protease for COVID-19 treatment

Insilico Medicine, a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, today announced its nomination of a novel preclinical candidate (PCC) targeting 3C-like (3CL) protease for the treatment of COVID-19.

24 May 2022

Research may lead to new generation of long-lasting medical implants

Scientists from the Tokyo Medical and Dental University used photoelectrochemical measurement and X-ray photoelectron spectroscopy to clarify the source of titanium's biocompatibility when implanted into the body, as with hip replacements and dental implants.

24 May 2022

Researchers adapt microbubbles to become more potent tools for cancer therapy

Microbubbles can assist with localized drug delivery in a patient's body by popping at a target site to create enhanced permeability of tumor blood vessels.

24 May 2022

Survey: Parents are generally receptive to the use of AI tools in pediatric ED, but reservations remain

Parents are generally receptive to the use of artificial intelligence (AI) tools in the management of children with respiratory illnesses in the Emergency Department (ED), according to a survey from Ann & Robert H. Lurie Children's Hospital of Chicago.

24 May 2022

Computational modeling fine tunes RBD-1C aptamer against SARS-CoV-2 S protein

Researchers used the SARS-CoV-2 sequence against aptamers to perform the in silico selection of an aptamer against the SARS-CoV-2 S protein.

24 May 2022

Medical News

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Largest study to date on long COVID identifies a broad list of diagnoses

Living in areas with high social vulnerability associated with worse outcomes after traumatic injury

Anosmia in pediatric COVID-19

Son preference may impact Nepali girls’ health and well-being in complex, nuanced ways

New study counters claims that COVID-19 vaccines reduce fertility and affect fetal growth

Anti-SARS-CoV-2 antibodies from breast milk persist in infants’ digestive tract

Study estimates $1.8 billion in Medicare spending on drugs with accelerated approval

Hydration restores airway integrity in people with cystic fibrosis

Engineered water nanostructures as a new technology against SARS-CoV-2

Changes in dopamine levels in the brain affect emotion-recognition

Study reports on the first instances of in-hospital, household transmission of monkeypox

Factors affecting exercise during COVID-19 pandemic

Detailed analysis shows women who have twins are not more fertile

COVID-19 vaccine effectiveness wanes more quickly in cancer patients, study finds

Insilico Medicine nominates novel preclinical candidate targeting 3CL protease for COVID-19 treatment

Research may lead to new generation of long-lasting medical implants

Researchers adapt microbubbles to become more potent tools for cancer therapy

Survey: Parents are generally receptive to the use of AI tools in pediatric ED, but reservations remain

Computational modeling fine tunes RBD-1C aptamer against SARS-CoV-2 S protein

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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