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Gene therapy approach delays disease onset in humanized mouse models of familial ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the progressive loss of motor neurons in the brain and spinal cord responsible for voluntary movements and muscle control.

2 Aug 2022

Research could pave the way for therapeutic strategies targeting DCIR to treat colorectal tumors

Colorectal tumors are a common adverse effect of chronic inflammation of the intestine. In a new study, researchers from Japan and China demonstrate that mice models with dendritic cell immunoreceptor (DCIR) protein deficiency are resistant to colonic tumors induced by dextran sodium sulfate and azoxymethane.

2 Aug 2022

Gout flares associated with subsequent cardiovascular events

Experts at the University of Nottingham, in collaboration with experts at Keele University, have found that the risk of heart attacks and strokes temporarily increases in the four months after a gout flare.

2 Aug 2022

New treatment gives hope for people challenged with chronic back pain

People challenged with chronic back pain have been given hope with a new treatment that focuses on retraining how the back and the brain communicate, a randomized controlled trial run by researchers at UNSW Sydney and Neuroscience Research Australia and several other Australian and European universities has shown.

2 Aug 2022

Study identifies pivotal role of FIBCD1 gene in neurodevelopmental disorders

A multidisciplinary study led by Vanja Nagy (LBI-RUD/CeMM/Medical University of Vienna) and Josef Penninger (UBC/IMBA) characterized a novel gene, known as FIBCD1, to be likely causative of a new and rare neurodevelopmental disorder.

2 Aug 2022

IRB Barcelona researchers discover genetic drivers of clonal hematopoiesis

Clonal hematopoiesis is a biological process in which a blood stem cell (the population that gives rise to a variety of blood cell types) acquires an advantageous mutation and outgrows neighboring cells.

2 Aug 2022

Hormonal treatment provides long-term benefit for premenopausal women with breast cancer

To investigate the long-term benefit of hormone-lowering treatment, researchers at Karolinska Institutet in Sweden have done a 20-year follow-up of premenopausal women with breast cancer.

2 Aug 2022

Miniature surgical robot gets ready for a 2024 test mission aboard the ISS

A miniaturized robot invented by Nebraska’s Shane Farritor is on scheduled to blast off into space to showcase its skills.

2 Aug 2022

Smaller lung airways in women can lead to a higher risk for COPD

Structural differences in lung airways between men and woman may be the cause of differences in chronic obstructive pulmonary disease (COPD) prevalence and outcomes between the sexes.

2 Aug 2022

New, non-invasive imaging method may help detect an early indicator of glaucoma

A new, non-invasive ocular imaging method may be able to detect an early indicator of glaucoma in time to prevent disease progression and vision loss, according to a new study from New York Eye and Ear Infirmary of Mount Sinai.

2 Aug 2022

Microvascular disease and Alzheimer's associated with more white matter damage, more inflammation

Disease of the microscopic blood vessels that feed the white matter of our brain is associated with worse cognitive function and memory deficits in individuals with Alzheimer's, scientists report.

2 Aug 2022

Human anti-desmoglein 2 levels are associated with COVID-19 severity

In a new study, researchers assessed the association between anti-desmoglein (DSG) 1, 2 and 3 auto-antibodies (auto-Abs) in acute and convalescent serum samples obtained from patients with COVID-19 of varying severity.

2 Aug 2022

Acupuncture therapy may be a useful tool to ward off type 2 diabetes

It's been used for thousands of years to treat a variety of illnesses - and now acupuncture could also help fight one of the 21st century's biggest health challenges.

2 Aug 2022

Socioeconomic deprivation associated with increased dementia risk and faster memory decline

Socioeconomic deprivation, including neighborhood disadvantages and persistent low wages, are associated with higher dementia risk, lower cognitive performance and faster memory decline, according to several studies reported today at the Alzheimer’s Association International Conference 2022 in San Diego and virtually.

2 Aug 2022

17 recommendations for better communication with study participants affected by early stopping of clinical trials

Participants in clinical trials can feel abandoned and adrift when their studies end early and they are the last to be informed, or they hear about it first from news or social media.

2 Aug 2022

Two-thirds of Americans disapprove of ending ‘Roe,’ but it’s not a top voting issue

Barely a month after the Supreme Court overturned Roe v. Wade's federal guarantee of access to abortion, two-thirds of Americans said they disapprove of the court's decision and 6 in 10 said they want their states to make abortion legal, a new poll finds.

2 Aug 2022

Pre-existing anti-SARS-CoV-2 immunity decreases viral spread but increase SARS-CoV-2 Omicron competitiveness in hamsters

In a new study, researchers assessed the impact of pre-existing immunity against SARS-CoV-2 acquired by previous infections (PI) or COVID-19 vaccination on the transmission of SARS-CoV-2 variants of concern such as Delta and Omicron.

2 Aug 2022

Study sheds light on the role of blood pressure self-monitoring in diabetes management

JMIR Publications recently published "Blood Pressure Monitoring as a Digital Health Tool for Improving Diabetes Clinical Outcomes: Retrospective Real-world Study" in the Journal of Medical Internet Research (JMIR), which reported that there is a lack of understanding of the association between blood glucose (BG) and blood pressure (BP) levels when using digital health tools.

2 Aug 2022

VR balance training is highly effective in improving balance ability of patients with Parkinson's disease

JMIR Publications recently published "Benefits of Virtual Reality Balance Training for Patients With Parkinson Disease: Systematic Review, Meta-analysis, and Meta-Regression of a Randomized Controlled Trial" in JMIR Serious Games, which reported that virtual reality (VR) balance training is increasingly being pursued in biomedical research, specifically with respect to investigating balance ability with VR.

2 Aug 2022

Validating the accuracy of Cloud DX Vitaliti continuous vital signs monitor

JMIR Publications recently published "Continuous Noninvasive Remote Automated Blood Pressure Monitoring With Novel Wearable Technology: A Preliminary Validation Study" in JMIR mHealth and uHealth which reported that the aim of the study was to validate the accuracy of Cloud DX Vitaliti continuous vital signs monitor (CVSM) continuous noninvasive blood pressure (cNIBP) measurements in postsurgical patients.

2 Aug 2022

Medical News

Gene therapy approach delays disease onset in humanized mouse models of familial ALS

Research could pave the way for therapeutic strategies targeting DCIR to treat colorectal tumors

Gout flares associated with subsequent cardiovascular events

New treatment gives hope for people challenged with chronic back pain

Study identifies pivotal role of FIBCD1 gene in neurodevelopmental disorders

IRB Barcelona researchers discover genetic drivers of clonal hematopoiesis

Hormonal treatment provides long-term benefit for premenopausal women with breast cancer

Miniature surgical robot gets ready for a 2024 test mission aboard the ISS

Smaller lung airways in women can lead to a higher risk for COPD

New, non-invasive imaging method may help detect an early indicator of glaucoma

Microvascular disease and Alzheimer's associated with more white matter damage, more inflammation

Human anti-desmoglein 2 levels are associated with COVID-19 severity

Acupuncture therapy may be a useful tool to ward off type 2 diabetes

Socioeconomic deprivation associated with increased dementia risk and faster memory decline

17 recommendations for better communication with study participants affected by early stopping of clinical trials

Two-thirds of Americans disapprove of ending ‘Roe,’ but it’s not a top voting issue

Pre-existing anti-SARS-CoV-2 immunity decreases viral spread but increase SARS-CoV-2 Omicron competitiveness in hamsters

Study sheds light on the role of blood pressure self-monitoring in diabetes management

VR balance training is highly effective in improving balance ability of patients with Parkinson's disease

Validating the accuracy of Cloud DX Vitaliti continuous vital signs monitor

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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