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Optibrium Adds Augmented Intelligence for Compound Design to its StarDrop Small Molecule Drug Discovery Software

Optibrium Ltd, a leading developer of software for drug discovery, today announced the release of the latest version of StarDrop™, its comprehensive software platform for small molecule design, optimisation, and data analysis.

From Optibrium Ltd. 2 Mar 2022

Drug misuse is not exclusive to the opioid epidemic, suggests study

Drug misuse is not exclusive to the opioid epidemic, according to a recent West Virginia University study. Every year, about 50,000 people in the United States are admitted to the emergency room due to misuse of a common over-the-counter pain medication – acetaminophen.

2 Mar 2022

Targeting necroptosis using a necroptosis inhibitor lessens myositis-induced muscle weakness

A new study has suggested that treatment to target necroptosis in muscle fibers using a necroptosis inhibitor lessens myositis-induced muscle weakness as well as muscle cell death and inflammation in the muscles. This has been shown to be a promising strategy for treating polymyositis.

2 Mar 2022

Study finds booster shot did produce effective levels of neutralizing antibodies against omicron

A new study using serum from human blood samples suggests neutralizing antibody levels produced by two-dose mRNA vaccines against the original and early variants of the SARS-CoV-2 virus wane substantially over time, and offer essentially no protection against the omicron variant.

2 Mar 2022

Researchers explore a human speech recognition model based on machine learning

Hearing loss is a rapidly growing area of scientific research as the number of baby boomers dealing with hearing loss continues to increase as they age.

2 Mar 2022

Researchers identify directed interactions between brain areas and confirmed patterns of activity

Exploring how brain areas communicate with each other is the focus of a long-standing research collaboration between Carnegie Mellon University, Albert Einstein College of Medicine, and Champalimaud Research.

2 Mar 2022

People in England limited contact with others even outside of lockdown periods, suggests study

Transmission of respiratory viruses depends partly on the rate of close social contacts in a population. A study publishing March 1st in PLOS Medicine by Amy Gimma at the London School of Hygiene and Tropical Medicine, United Kingdom, and colleagues suggests that during the most restrictive period of lockdown in the United Kingdom, the number of reported contacts decreased by 75% from pre-pandemic levels.

2 Mar 2022

Telehealth services were highly utilized by individuals with multiple sclerosis during COVID-19

While many people skipped regular health check-ups during the COVID-19 pandemic, new research indicates that people with multiple sclerosis (MS) used online telehealth services more frequently to keep in contact with their health care providers and were highly satisfied with the outcome.

1 Mar 2022

A ubiquitous protein may be key to the survival of neurons most impacted by glaucoma

A ubiquitous protein called sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of the neurons most impacted by glaucoma, scientists report.

1 Mar 2022

Developmental delays related to Leigh syndrome may occur earlier than previously known

Researchers from the Mitochondrial Medicine Frontier Program at Children's Hospital of Philadelphia have found that developmental delays associated with Leigh syndrome, the most common pediatric mitochondrial disorder, may occur earlier than previously recognized – even before metabolic stroke and regression – which could provide clinicians with an opportunity for earlier diagnosis and therapeutic interventions.

1 Mar 2022

Masks made of woven fabrics are lousy air filters

Like many other viruses, COVID-19 is transmitted primarily via particles carried in the air. An infected person breathes out particles containing the virus into the air, which can then be inhaled by another person, who then becomes infected.

1 Mar 2022

New technology can assist bioprosthetic heart valve patients by avoiding additional replacement surgery

An international study led by a researcher from Tel Aviv University offers a novel technology that can assist many patients implanted with bioprosthetic heart valve by avoiding additional complicated replacement surgery.

1 Mar 2022

Repeat surgery for recurrence is common among hernia patients

About one in six older Americans who'd undergone an operation to repair a hernia had repeat hernia surgery less than 10 years later, Michigan Medicine research found.

1 Mar 2022

Scientists reveal molecular mechanisms behind bone loss caused by chronic liver injury

A research team led by Prof. Chen Di from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences along with other collaborators have revealed the molecular mechanisms behind bone loss caused by chronic liver injury.

1 Mar 2022

Early menopause puts women at greater risk of dementia later in life

Women who enter menopause very early, before age 40, were found to be more likely to develop dementia of any type later in life compared to women who begin menopause at the average menopause-onset age of 50 to 51 years, according to preliminary research to be presented at the American Heart Association's Epidemiology, Prevention, Lifestyle & Cardiometabolic Health Conference 2022.

1 Mar 2022

Phase 2/3 study of oral RHB-107 in non-hospitalized COVID-19 patients shows promising results

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced positive top-line results from the Phase 2 part of the Phase 2/3 study of once-daily oral RHB-107 (upamostat) in non-hospitalized symptomatic COVID-19 patients, predominantly conducted in the U.S. (60/61 patients) as well as South Africa.

1 Mar 2022

Research sheds light on the role of lipids in Alzheimer’s disease development

Neurons in the brain coexist with and rely on many other cell types to function properly. Astrocytes, which take their name from their star shape, ensure the survival of neurons by feeding and detoxifying them with the help of a multifunctional protein, APOE.

1 Mar 2022

Medical News

Optibrium Adds Augmented Intelligence for Compound Design to its StarDrop Small Molecule Drug Discovery Software

Drug misuse is not exclusive to the opioid epidemic, suggests study

Targeting necroptosis using a necroptosis inhibitor lessens myositis-induced muscle weakness

Study finds booster shot did produce effective levels of neutralizing antibodies against omicron

Researchers explore a human speech recognition model based on machine learning

Researchers identify directed interactions between brain areas and confirmed patterns of activity

People in England limited contact with others even outside of lockdown periods, suggests study

Telehealth services were highly utilized by individuals with multiple sclerosis during COVID-19

A ubiquitous protein may be key to the survival of neurons most impacted by glaucoma

Developmental delays related to Leigh syndrome may occur earlier than previously known

Masks made of woven fabrics are lousy air filters

New technology can assist bioprosthetic heart valve patients by avoiding additional replacement surgery

Repeat surgery for recurrence is common among hernia patients

Scientists reveal molecular mechanisms behind bone loss caused by chronic liver injury

Early menopause puts women at greater risk of dementia later in life

Phase 2/3 study of oral RHB-107 in non-hospitalized COVID-19 patients shows promising results

Research sheds light on the role of lipids in Alzheimer’s disease development

Cleveland Clinic launches new study exploring the link between epilepsy and stress

Buccal cell epigenetic biomarkers may predict preterm birth

Researchers launch a multi-center trial to investigate new treatment for pediatric type 1 diabetes

How Programmable Nanobiology Could Drive the Fifth Industrial Revolution

Dr. Anthony Grice

Building quality into drug development for safer, faster medicines

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