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Encouraging in vitro results with SARS-CoV-2-spike-specific polyclonal antibody fragments

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated the potent neutralizing ability of a polyclonal equine antibody (Ab), FBR-002, against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs), including Omicron.

28 Feb 2022

Mechanisms leading to Parkinson's disease following SARS-CoV-2 infection

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated the impact of an amyloidogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protein fragment named SFYVYSRVK (SK9) on the α-synuclein (aS) monomers and fibrils, a potential risk factor for Parkinson's disease.

28 Feb 2022

COVID-19 severity is correlated with body composition

In a recent study posted to the medRxiv* preprint server, researchers assessed the effect of changes in the abdominal well-being and physique on coronavirus disease 2019 (COVID-19) severity using magnetic resonance imaging (MRI).

28 Feb 2022

Novel respiratory model predicts mechanisms altered by SARS-CoV-2 variants

Researchers study cell infection and viral replication methods affected by SARS-CoV-2 mutations through a novel respiratory model.

28 Feb 2022

New ultrasound scan can detect prostate cancer cases with good accuracy

An ultrasound scan can be used to detect cases of prostate cancer, according to new research.

28 Feb 2022

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

For the first time, researchers have revealed that during the development of Type 1 Diabetes (T1D), when insulin-producing cells in the pancreas are under attack from T lymphocytes, the cells lining the pancreatic duct reprogram themselves in an attempt to suppress autoimmune T cell responses.

28 Feb 2022

A study on the evolution of avian coronavirus escape mutants in vitro

A recent study included an in vitro assessment of the effect of antibody titers and vaccine combinations on the emergence of escape mutants of AvCoV.

28 Feb 2022

New portal launched to order personal protective equipment in England

A new online platform to order personal protective equipment (PPE) in England has been launched.

28 Feb 2022

Study finds higher mortality rates in older adults with cognitive issues during COVID-19 pandemic

Findings from a new study, led by researchers at Dartmouth’s Geisel School of Medicine and published in JAMA Neurology, show that higher death rates have been associated with the COVID-19 pandemic among older adults with cognitive impairment—especially in racial and ethnic minority populations and those living in nursing homes.

28 Feb 2022

Study compares heterologous and homologous third vaccination in kidney transplant recipients

A new study assesses the comparative neutralizing antibody level elicited by three mRNA vaccine doses to a heterologous COVID-19 vaccine regimen.

28 Feb 2022

First platform trial for ALS hopes to accelerate the development of effective treatments

A new paper in Annals of Neurology describes the approach, structure, and launch of the HEALEY ALS Platform Trial– the first platform trial for amyotrophic lateral sclerosis (ALS) designed to accelerate the development of effective and breakthrough treatments for people with the illness.

28 Feb 2022

Breakthrough SARS-CoV-2 infection peaks at 5 months

A new study describes the incidence of breakthrough infection with SARS-CoV-2 after vaccination with one of the nucleic acid or viral vector vaccines.

28 Feb 2022

Updated guideline released for managing antirheumatic drugs in patients undergoing hip or knee replacement

The American College of Rheumatology and the American Association of Hip and Knee Surgeons released a summary of their updated guideline for the Perioperative Management of Antirheumatic Medication in Patients with Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty.

28 Feb 2022

New review highlights lack of women in leadership positions on cardiovascular clinical trials

Women remain underrepresented in leading cardiovascular clinical trials, which corresponds with underrepresentation and a lack of gender diversity among presenters at scientific meetings, according to a review published today in the Journal of the American College of Cardiology.

28 Feb 2022

Alcohol consumption may be a modifiable risk factor for age-related macular degeneration

Even though Dry January is over, new research suggests you may want to consider keeping the no-alcohol challenge going all year, especially if you're among the nearly 2 million Americans who have age-related macular degeneration (AMD), a sight-threatening eye condition.

28 Feb 2022

Researchers show a relationship between regionalized myocardial fibrosis and mitral valve prolapse

The larger the sail, the more wind it catches. But as that size increases, so does the stress experienced by each sheet and line connected to the canvas.

28 Feb 2022

Study reveals the thalamocortical mechanism for nostalgia-induced analgesia

Ever noticed that looking at photos of good times with family or friends diminishes the pain of your headache? Nostalgia has already been shown to be helpful with pain relief, and a new study has now revealed the thalamocortical mechanism for nostalgia-induced analgesia.

28 Feb 2022

Research shows intergenerational effects of preconception opioids in male offspring rats

New research from scientists at Cummings School of Veterinary Medicine at Tufts University suggests opioid use before pregnancy - even if not used during pregnancy itself - could result in a higher likelihood that a mother's male offspring will develop type 2 diabetes and metabolic syndrome, conditions that increase the risk of heart disease and stroke.

28 Feb 2022

Peer-led online communities effective in increasing HIV self-testing among MSM of color

A new University of California, Irvine-led study, called the HOPE (Harnessing Online Peer Education) HIV study, revealed that using peer-led online communities was successful in increasing HIV self-testing and reducing alcohol consumption among Latinx and African American MSM (men who have sex with men).

28 Feb 2022

Novel molecular pathway shared by two neurodegenerative disorders discovered

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

28 Feb 2022

Medical News

Encouraging in vitro results with SARS-CoV-2-spike-specific polyclonal antibody fragments

Mechanisms leading to Parkinson's disease following SARS-CoV-2 infection

COVID-19 severity is correlated with body composition

Novel respiratory model predicts mechanisms altered by SARS-CoV-2 variants

New ultrasound scan can detect prostate cancer cases with good accuracy

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

A study on the evolution of avian coronavirus escape mutants in vitro

New portal launched to order personal protective equipment in England

Study finds higher mortality rates in older adults with cognitive issues during COVID-19 pandemic

Study compares heterologous and homologous third vaccination in kidney transplant recipients

First platform trial for ALS hopes to accelerate the development of effective treatments

Breakthrough SARS-CoV-2 infection peaks at 5 months

Updated guideline released for managing antirheumatic drugs in patients undergoing hip or knee replacement

New review highlights lack of women in leadership positions on cardiovascular clinical trials

Alcohol consumption may be a modifiable risk factor for age-related macular degeneration

Researchers show a relationship between regionalized myocardial fibrosis and mitral valve prolapse

Study reveals the thalamocortical mechanism for nostalgia-induced analgesia

Research shows intergenerational effects of preconception opioids in male offspring rats

Peer-led online communities effective in increasing HIV self-testing among MSM of color

Novel molecular pathway shared by two neurodegenerative disorders discovered

How Programmable Nanobiology Could Drive the Fifth Industrial Revolution

Dr. Anthony Grice

Building quality into drug development for safer, faster medicines

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