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Noncovalent protease inhibitors against SARS-CoV-2 and other coronaviruses

In a new study published in ACS Infectious Diseases journal, scientists biochemically and structurally evaluated the PLpro from a subgroup 2b bat coronavirus, BtSCoV-Rf1.2004, to identify unique structural features or enzymatic biases of the subgroup 2b.

28 Feb 2022

Vaccination reduces risk of long-COVID

A new study posted on the medRxiv* preprint server investigated the difference between the likelihood of symptoms, 12 weeks after SARS-CoV-2 infection, among individuals who received two COVID-19 vaccination doses and unvaccinated individuals.

27 Feb 2022

SARS-CoV-2 monitoring could be improved with use of bacterial metatranscriptomes in wastewater

In a recent research report from the United States, currently available on bioRxiv* preprint server, scientists have shown that bacterial taxonomic and functional profiles can discriminate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) status even without directly detecting viral transcripts – opening the door for entirely novel approaches in wastewater-based epidemiology.

27 Feb 2022

No seroprevalence observed against SARS-CoV-2 in wild ruminants in Germany

A team of scientists from Germany has recently conducted a serological screening on wild animals to assess seroprevalence against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other pathogenic viruses related to domestic ruminants.

27 Feb 2022

Lunchtime walks on a hot day impairs cognitive performance, study finds

Studies have shown that being in a hot environment reduces cognitive performance, whereas a brief walk enhances cognition.

27 Feb 2022

Antibiotics provide no benefit in preventing recurrent wheezing in infants hospitalized with RSV

Antibiotics provide no benefit in preventing future recurrent wheezing in babies hospitalized with respiratory syncytial virus (RSV), according to a new study led by Washington University School of Medicine in St. Louis. And there is some evidence that antibiotics may make wheezing worse.

27 Feb 2022

Study determines effectiveness of COVID-19 vaccination against Omicron variant in high-risk indoor settings

A new study estimates vaccine effectiveness against SARS-CoV-2 Omicron variant in indoor entertainment settings in Australia.

27 Feb 2022

New dialysis system shows ability to make sterile, medical grade water at the point-of-care

Findings from preliminary tests of a new dialysis system have confirmed its ability to make sterile, medical grade water to provide an affordable, accessible home-based treatment option for patients with kidney failure.

27 Feb 2022

Will Omicron BA.2 become the next dominant variant?

A new study presents a comprehensive analysis of the potential of both Omicron BA.2 and BA.3 to become the next dominant circulating SARS-CoV-2 strain.

27 Feb 2022

Clinical trial shows encouraging results with fecal microbiota transplants for peanut-allergic patients

Peanut allergies are hard to treat and can cause fatal or near-fatal anaphylactic reactions. People usually don't outgrow peanut allergy, requiring lifelong scrutiny of food labels to avoid even small traces of peanut.

27 Feb 2022

Emergence of SARS-CoV-2 Omicron likely due to immune selective pressure

A new study discusses the emergence of new variants of SARS-CoV-2 that can escape antibody-mediated neutralization, as opposed to other Sarbecoviruses.

27 Feb 2022

Oral health disparities persist and pose a major global public health threat, experts say

Americans' oral health has improved over the last two decades, but disparities in oral health have stubbornly persisted and pose a major global public health threat, write National Institute of Dental and Craniofacial Research Director Rena N. D'Souza, D.D.S., Ph.D., Science Advisor to the President and former National Institutes of Health Director Francis S. Collins, M.D., Ph.D., and U.S. Surgeon General Vivek H. Murthy, M.D., M.B.A., in a new perspective published in The New England Journal of Medicine.

27 Feb 2022

Mechanism behind how certain osmolytes cause kidney damage revealed

Researchers from Tokyo Metropolitan University have uncovered the mechanism by which osmolytes used to treat high fluid pressure in the eye and skull can cause kidney damage.

27 Feb 2022

Altered microbiomes in SARS-CoV-2 infection pose threat of antibiotic resistance

A new study discusses changes in the microbiota of various parts of the body with SARS-CoV-2 infection.

27 Feb 2022

Study finds waning protection of COVID-19 vaccines after six months

A study released in The Lancet Respiratory Medicine by Providence, one of the largest health systems in the United States, confirms the overall effectiveness of vaccines in preventing severe infection resulting in hospitalization from Covid-19, but also shows a substantial decline in protection after six months.

27 Feb 2022

Adherence promotion strategy reduces costs, improves outcomes for adolescent transplant recipients

Analysis of an adherence promotion strategy, the Medication Adherence Promotion System (MAPS), found that healthcare systems will save over $9,000 per adolescent transplant recipient compared to usual care.

27 Feb 2022

The epidemiology of COVID-19 in Africa

A new study uses the Africa CDC generic protocol for obtaining COVID-19 seroprevalence data to understand the spread and epidemiology of SARS-CoV-2.

27 Feb 2022

A promising new vaccine for SARS-CoV-2 and influenza

Researchers create a vaccine candidate that could protect against both SARS-CoV-2 and IAVs.

27 Feb 2022

Study provides better understanding of risk factors for postpartum depression

The risk for postpartum depression is highest among first-time mothers, mothers younger than 25 years old and mothers of twins, according to a survey of more than 1.1 million moms worldwide.

25 Feb 2022

Viewing nostalgic images reduces pain perception

Reflecting on fond memories goes a step beyond making you feel warm and fuzzy: nostalgia can reduce pain perception. Nostalgia decreases activity in pain-related brain areas and decreases subjective ratings of thermal pain, according to research recently published in JNeurosci.

25 Feb 2022

Medical News

Noncovalent protease inhibitors against SARS-CoV-2 and other coronaviruses

Vaccination reduces risk of long-COVID

SARS-CoV-2 monitoring could be improved with use of bacterial metatranscriptomes in wastewater

No seroprevalence observed against SARS-CoV-2 in wild ruminants in Germany

Lunchtime walks on a hot day impairs cognitive performance, study finds

Antibiotics provide no benefit in preventing recurrent wheezing in infants hospitalized with RSV

Study determines effectiveness of COVID-19 vaccination against Omicron variant in high-risk indoor settings

New dialysis system shows ability to make sterile, medical grade water at the point-of-care

Will Omicron BA.2 become the next dominant variant?

Clinical trial shows encouraging results with fecal microbiota transplants for peanut-allergic patients

Emergence of SARS-CoV-2 Omicron likely due to immune selective pressure

Oral health disparities persist and pose a major global public health threat, experts say

Mechanism behind how certain osmolytes cause kidney damage revealed

Altered microbiomes in SARS-CoV-2 infection pose threat of antibiotic resistance

Study finds waning protection of COVID-19 vaccines after six months

Adherence promotion strategy reduces costs, improves outcomes for adolescent transplant recipients

The epidemiology of COVID-19 in Africa

A promising new vaccine for SARS-CoV-2 and influenza

Study provides better understanding of risk factors for postpartum depression

Viewing nostalgic images reduces pain perception

How Programmable Nanobiology Could Drive the Fifth Industrial Revolution

Dr. Anthony Grice

Building quality into drug development for safer, faster medicines

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