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Study finds better immunotherapy response in lung cancer patients with genetic variant linked to autoimmune disease

A variant of the CTLA-4 gene associated with autoimmune disease was found to be more frequent in non-small cell lung cancer (NSCLC) patients who experienced an exceptionally high response to anti-PD-1 immunotherapy and higher immune-related side effects than in a comparable cohort of lung cancer patients and healthy individuals, according to data presented during the AACR Annual Meeting 2022, held April 8-13.

10 Apr 2022

Common dishwashing detergents may eliminate coronaviruses from glass

Common dishwashing detergents and scrubbing devices found to be sufficient to inactivate and eliminate human coronaviruses from glass surfaces.

10 Apr 2022

NK cells complexed with bispecific antibody elicit high response rate in patients with resistant lymphomas

Natural killer (NK) cells derived from cord blood that were activated and complexed with a CD30/CD16A bispecific antibody elicited an 89 percent overall response rate in patients with relapsed or refractory CD30+ lymphoma, according to results from a phase I/II clinical trial presented at the AACR Annual Meeting 2022, held April 8-13.

10 Apr 2022

NSCLC patients treated with KRAS G12C inhibitor sotorasib may receive long-term clinical benefit

Patients with non-small cell lung cancer (NSCLC) treated with the KRAS G12C inhibitor sotorasib (Lumakras) had a two-year overall survival rate of 32.5 percent, according to data from the CodeBreaK 100 clinical trial presented during the AACR Annual Meeting 2022, held April 8-13.

10 Apr 2022

Preliminary data from clinical trial reveals safety, efficacy of new CAR T-cell therapy for solid tumors

A new chimeric antigen receptor (CAR) T-cell product had an acceptable safety profile and showed early signs of efficacy as a monotherapy and in combination with an mRNA vaccine in patients with solid tumors, according to preliminary data from a phase I/II clinical trial presented during the AACR Annual Meeting 2022, held April 8-13.

10 Apr 2022

Consumption of healthy plant-based foods linked with lower risk of developing type 2 diabetes

New research published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]) finds that the consumption of healthy plant-based foods, including fruits, vegetables, nuts, coffee, and legumes, is associated with a lower risk of developing type 2 diabetes (T2D) in generally healthy people and support their role in diabetes prevention.

10 Apr 2022

Novel therapy advances to clinical trial for the treatment of glioblastoma

A novel therapy studied at the Medical College of Wisconsin (MCW) Cancer Center has led to a clinical trial for the treatment of glioblastoma, a rare and aggressive form of brain cancer, yet the most common primary brain tumor in adults.

10 Apr 2022

Researchers provide insight into anatomical position of the sacral mesh during laparoscopic procedure

A May 2022 study published in the Diseases of the Colon and Rectum zooms in on the importance of anatomy. Dr. Argeny and colleagues of the Medical University of Vienna, Austria, provide insight into the anatomical position of the mesh in relation to the sacrum during a laparoscopic procedure.

10 Apr 2022

UK Minister for Africa visited Malawi to highlight a strong, forward-looking relationship

On her first visit to Malawi since her appointment as Minister for Africa, Vicky Ford visited UK Aid-funded projects which support women and girls access health services, education and private sector development in the country.

10 Apr 2022

B-cells have significant differences in women with postpartum depression, finds study

A study published in Molecular Psychiatry is the first to look at multiple levels of biology within women with postpartum depression (PPD) to see how women with the condition differ from those without it.

10 Apr 2022

Study shows benefits of Medicaid expansion for patients diagnosed with de novo stage 4 breast cancer

A new study led by Susan G. Komen® Scholars indicates that patients diagnosed with de novo stage 4 breast cancer – also called metastatic breast cancer– had improved survival rates and decreased mortality rates when those patients had access to care.

10 Apr 2022

Simple interventions reduced radiation exposure to the heart during lung cancer treatment

Radiation to the heart during treatment for locally advanced lung cancer is associated with an increased risk of major adverse cardiac events within the first two years following treatment. The higher the cardiac dose exposure, the higher the risk of a cardiac event.

8 Apr 2022

Cancer risk and related mortality significantly higher among patients with kidney disease

Patients with kidney disease may have an increased risk of cancer and may be more likely to die from cancer.

8 Apr 2022

Imbalances in the intestinal virome may promote inflammatory bowel disease, research shows

Research in recent years has demonstrated the diverse roles that gut bacteria can play in health and disease, but what about contributions from viruses, which, like bacteria, perpetually reside within the human intestine?

8 Apr 2022

Study gains insight into the reasons behind low rate of birth registrations in Africa

In large parts of Africa, only half of all children are registered at birth. As a result, these unregistered children cannot, or only with difficultly, make claim to essential human rights later in life, be it healthcare, education or financial support.

8 Apr 2022

New delivery method enhances the "attack power" of CAR T cells against tumors

One cutting-edge cancer treatment exciting researchers today involves collecting and reprogramming a patient's T cells – a special set of immune cells – then putting them back into the body ready to detect and destroy cancerous cells.

8 Apr 2022

Study reveals rapid increases in urban exposure to air pollutants hazardous to health

The international team of scientists aimed to address data gaps in air quality for 46* future megacities in Africa, Asia and the Middle East using space-based observations from instruments onboard NASA and European Space Agency (ESA) satellites for 2005 to 2018.

8 Apr 2022

Combination immunotherapy reverses resistance to PD-1 inhibitors in patients with advanced melanoma

Patients with advanced melanoma whose cancer does not respond to treatment with widely used immunotherapy drugs known as PD-1 inhibitors are often switched to treatment with a second type of immunotherapy drug – a CTLA-4 inhibitor such as the drug ipilimumab.

8 Apr 2022

Computational network science approach reveals new mechanisms for coronaviruses infections

A group of bat viruses related to SARS-CoV-2 can also infect human cells but uses a different and unknown entryway.

8 Apr 2022

City of Hope's late-breaking clinical trial data to be presented at AACR

Researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, will present late-breaking and clinical trial findings at this year's American Association for Cancer Research Annual Meeting, which begins today.

8 Apr 2022

Medical News

Study finds better immunotherapy response in lung cancer patients with genetic variant linked to autoimmune disease

Common dishwashing detergents may eliminate coronaviruses from glass

NK cells complexed with bispecific antibody elicit high response rate in patients with resistant lymphomas

NSCLC patients treated with KRAS G12C inhibitor sotorasib may receive long-term clinical benefit

Preliminary data from clinical trial reveals safety, efficacy of new CAR T-cell therapy for solid tumors

Consumption of healthy plant-based foods linked with lower risk of developing type 2 diabetes

Novel therapy advances to clinical trial for the treatment of glioblastoma

Researchers provide insight into anatomical position of the sacral mesh during laparoscopic procedure

UK Minister for Africa visited Malawi to highlight a strong, forward-looking relationship

B-cells have significant differences in women with postpartum depression, finds study

Study shows benefits of Medicaid expansion for patients diagnosed with de novo stage 4 breast cancer

Simple interventions reduced radiation exposure to the heart during lung cancer treatment

Cancer risk and related mortality significantly higher among patients with kidney disease

Imbalances in the intestinal virome may promote inflammatory bowel disease, research shows

Study gains insight into the reasons behind low rate of birth registrations in Africa

New delivery method enhances the "attack power" of CAR T cells against tumors

Study reveals rapid increases in urban exposure to air pollutants hazardous to health

Combination immunotherapy reverses resistance to PD-1 inhibitors in patients with advanced melanoma

Computational network science approach reveals new mechanisms for coronaviruses infections

City of Hope's late-breaking clinical trial data to be presented at AACR

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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