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SARS-CoV-2 mutated spike proteins show variations in cell entry

A new study by Japanese scientists published on the preprint server bioRxiv* in June 2020 shows that the D614g mutation in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein can enhance the infectivity of the virus while leaving it vulnerable to neutralization by antibodies.

17 Jun 2020

Novel ACE2-antibody fusion molecules show anti-SARS-CoV-2 activity

Now, in a new study published on the preprint server, bioRxiv researchers in the U.S. investigated a soluble version of ACE2 for SARS-CoV-2 viral neutralization activity.

17 Jun 2020

Norway pulls coronavirus contact tracing App due to privacy concerns

Amid the coronavirus pandemic, many countries have launched contact tracing apps to help contain the spread of the virus. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread across most of the world, now infecting more than 8.17 million people; hence, extensive contact tracing is a vital tool to prevent its vast spread.

17 Jun 2020

Beijing lockdown due to new SARS-CoV-2 cluster, New Zealand records first case in weeks

China had started to return to normalcy after successfully "flattening the curve," with the government slowly easing restrictions and opening up the economy. However, Beijing has reported new clusters of coronavirus disease (COVID-19) cases, prompting the implementation of lockdown measures.

17 Jun 2020

Scientists isolate powerful SARS-CoV-2 -neutralizing antibodies from COVID-19 patients

A new study has shown that potent antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could help protect against COVID-19 infection. Preliminary results in animal studies have so far proven successful. The study titled, "Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model," was published in the latest issue of the journal Science.

17 Jun 2020

CSIRO study on the effects of COVID-19 on weight and well being

The CSIRO, Australia's federal government agency responsible for scientific research, has come up with a study looking at the emotional well being and weight loss or gain associated with the COVID-19 pandemic and the forced stay-at-home measures.

16 Jun 2020

Antibiotic X-206 effective against SARS-CoV-2 in vitro

The current study published on the preprint server bioRxiv aims to understand how these compounds affect SARS-CoV-2 in vitro. The researchers from Aarhus University in Denmark examined 11 natural PEIs, with a single synthetic analog, screening them for inhibitory activity against the CPE of SARS-CoV-2 infecting cultured cells with overexpression of TMPRSS2, a serine protease that is instrumental in cleaving the spike protein of the virus.

16 Jun 2020

Study: One in five adults experienced a decrease in their sexual behavior early in the pandemic

One in five adults in the United States report they have experienced change - mostly a decrease - in their sexual behavior during the early months of the COVID-19 pandemic, according to a new study by Indiana University researchers.

16 Jun 2020

How antibodies neutralize SARS-CoV-2 in convalescent patients

A new study by researchers from the United Kingdom and Taiwan and published on the preprint server bioRxiv in June 2020 describes the structural basis for the neutralizing effect of the SARS-CoV-2 antibody on the virus. This also indicates a possible therapeutic molecule by identifying its binding epitope as possibly a major neutralizing site.

16 Jun 2020

Anti-TNF drug preserves beta-cell function in newly diagnosed pediatric patients with Type 1 diabetes

In research led by a University at Buffalo pediatric endocrinologist, a drug called golimumab showed that it preserved beta-cell function in children and young adults with newly diagnosed Type 1 diabetes, according to findings from a Phase 2 study.

16 Jun 2020

TERAVOLT tracks outcomes of people with thoracic cancers affected by COVID-19

New data from TERAVOLT, a global consortium that tracks outcomes of people with thoracic cancers affected by COVID-19, offers clues as to why they experienced a high death rate of 33% when the coronavirus swept across Europe.

16 Jun 2020

A new, daily home-monitoring program for patients presumed COVID-19 positive

How do you monitor patients who have COVID-19 symptoms but are not ill enough to come to the emergency department? And how do you help those patients feel cared about and less frightened while convalescing at home?

16 Jun 2020

Two potent small molecules appear to suppress tumor growth in multiple cancers

City of Hope scientists have identified and developed two potent small molecules that appear to suppress tumor growth in multiple cancers even when other treatments cease to work, possibly due to the development of drug resistance.

16 Jun 2020

Cancer results from interaction between individual’s genetics and exposure to carcinogens

A new study led by the University of Hawai?i Cancer Center looks into how and why certain individuals develop cancer and others do not.

16 Jun 2020

Scientists evaluate SARS-CoV-2 infection risks in livestock, poultry, pets and wildlife

A large-scale single-cell screening endeavor on a wide variety of animals showed that cells targeted by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are most abundant in cats, but are also found in other animals – unveiling a valuable resource for controlling the ongoing disruptive coronavirus disease (COVID-19) pandemic.

16 Jun 2020

Experts evaluate options for treating cognitive deficits in multiple sclerosis

Experts in cognitive research evaluated the status of available treatments as well as promising strategies for treating cognitive deficits in multiple sclerosis.

16 Jun 2020

Key factors to "flattening the curve": Western Washington state's COVID-19 experience

Despite having the first confirmed case of coronavirus and the first major COVID-19 outbreak in the United States, the state of Washington implemented a response plan that kept its death rate the lowest among all states that have had major outbreaks.

16 Jun 2020

Severity of COVID-19 linked to heparanase activity and heparan sulfate levels

Researchers at Radboud University Medical Center in the Netherlands reported an increase of heparanase activity and heparan sulfate levels in the plasma of patients with coronavirus disease (COVID-19), which was also associated with the severity of the condition – suggesting, in turn, potential treatment utility of low molecular weight heparins. The paper is currently available on the medRxiv* preprint server.

16 Jun 2020

Georgia Tech professor donated 7,000 gallons of redesigned sanitizer to fight COVID-19

So many people Seth Marder spoke to didn't see the hand sanitizer crisis brewing. The country was going to run dangerously short if someone did not act urgently.

16 Jun 2020

Persistent DNA damage in the placenta can affect embryonic growth

Scientists at the Stowers Institute for Medical Research have shown that a dysfunctional placenta can play a previously unrecognized role during the earliest stages of development in mouse models of Cornelia de Lange syndrome.

16 Jun 2020

Medical News

SARS-CoV-2 mutated spike proteins show variations in cell entry

Novel ACE2-antibody fusion molecules show anti-SARS-CoV-2 activity

Norway pulls coronavirus contact tracing App due to privacy concerns

Beijing lockdown due to new SARS-CoV-2 cluster, New Zealand records first case in weeks

Scientists isolate powerful SARS-CoV-2 -neutralizing antibodies from COVID-19 patients

CSIRO study on the effects of COVID-19 on weight and well being

Antibiotic X-206 effective against SARS-CoV-2 in vitro

Study: One in five adults experienced a decrease in their sexual behavior early in the pandemic

How antibodies neutralize SARS-CoV-2 in convalescent patients

Anti-TNF drug preserves beta-cell function in newly diagnosed pediatric patients with Type 1 diabetes

TERAVOLT tracks outcomes of people with thoracic cancers affected by COVID-19

A new, daily home-monitoring program for patients presumed COVID-19 positive

Two potent small molecules appear to suppress tumor growth in multiple cancers

Cancer results from interaction between individual’s genetics and exposure to carcinogens

Scientists evaluate SARS-CoV-2 infection risks in livestock, poultry, pets and wildlife

Experts evaluate options for treating cognitive deficits in multiple sclerosis

Key factors to "flattening the curve": Western Washington state's COVID-19 experience

Severity of COVID-19 linked to heparanase activity and heparan sulfate levels

Georgia Tech professor donated 7,000 gallons of redesigned sanitizer to fight COVID-19

Persistent DNA damage in the placenta can affect embryonic growth

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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